릴레이 치료학, Inc.
US ˙ NasdaqGM ˙ US75943R1023

SecurityRLAY / Relay Therapeutics, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership673,599 shares
Latest Disclosed Value $ 6,702,310
Renaissance Technologies Llc reports 3.97% increase in ownership of RLAY / Relay Therapeutics, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 673,599 shares of Relay Therapeutics, Inc. (US:RLAY) valued at $6,702,310 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 647,899 shares of Relay Therapeutics, Inc.. This represents a change in shares of 3.97% during the quarter. The current value of the position is $9,107,058 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F RELAY THERAPEUTICS COM 75943R102 673,599 25,700 3.97 6,702 22.28 0.0105
2026-02-12 2025-12-31 13F RELAY THERAPEUTICS COM 75943R102 647,899 -375,211 -36.67 5,481 2.64 0.0085
2025-11-13 2025-09-30 13F RELAY THERAPEUTICS COM 75943R102 1,023,110 -485,100 -32.16 5,341 2.34 0.0071
2025-08-13 2025-06-30 13F RELAY THERAPEUTICS COM 75943R102 1,508,210 -767,900 -33.74 5,218 -12.49 0.0069
2025-05-14 2025-03-31 13F RELAY THERAPEUTICS COM 75943R102 2,276,110 726,920 46.92 5,963 -6.57 0.0090
2025-02-13 2024-12-31 13F RELAY THERAPEUTICS COM 75943R102 1,549,190 878,095 130.85 6,383 34.33 0.0094
2024-11-13 2024-09-30 13F RELAY THERAPEUTICS COM 75943R102 671,095 -237,942 -26.18 4,751 -19.83 0.0071
2024-08-09 2024-06-30 13F RELAY THERAPEUTICS COM 75943R102 909,037 145,837 19.11 5,927 98,666.67 0.0101
2024-05-13 2024-03-31 13F RELAY THERAPEUTICS COM 75943R102 763,200 439,500 135.77 6 100.00 0.0100
2024-02-13 2023-12-31 13F RELAY THERAPEUTICS COM 75943R102 323,700 179,000 123.70 4 200.00 0.0055
2023-11-14 2023-09-30 13F RELAY THERAPEUTICS COM 75943R102 144,700 144,700 1 0.0021
2023-08-11 2023-06-30 13F RELAY THERAPEUTICS COM 75943R102 0 -118,854 -100.00 0 -100.00
2023-05-12 2023-03-31 13F RELAY THERAPEUTICS COM 75943R102 118,854 58,054 95.48 2 0.0026
2023-02-13 2022-12-31 13F RELAY THERAPEUTICS COM 75943R102 60,800 60,800 1 0.0012
2022-11-14 2022-09-30 13F RELAY THERAPEUTICS COM 75943R102 0 -25,900 -100.00 0 -100.00
2022-08-12 2022-06-30 13F RELAY THERAPEUTICS COM 75943R102 25,900 -1,900 -6.83 434 -47.84 0.0005
2022-05-13 2022-03-31 13F RELAY THERAPEUTICS COM 75943R102 27,800 20,800 297.14 832 286.98 0.0010
2022-02-11 2021-12-31 13F RELAY THERAPEUTICS COM 75943R102 7,000 -145,588 -95.41 215 -95.53 0.0003
2021-11-12 2021-09-30 13F RELAY THERAPEUTICS COM 75943R102 152,588 152,588 4,811 0.0062
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.