PTC Therapeutics, Inc.
US ˙ NasdaqGS ˙ US69366J2006

SecurityPTCT / PTC Therapeutics, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership533,300 shares
Latest Disclosed Value $ 36,333,729
Renaissance Technologies Llc reports 12.23% decrease in ownership of PTCT / PTC Therapeutics, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 533,300 shares of PTC Therapeutics, Inc. (US:PTCT) valued at $36,333,729 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 607,589 shares of PTC Therapeutics, Inc.. This represents a change in shares of -12.23% during the quarter. The current value of the position is $37,848,301 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F PTC THERAPEUTICS COM 69366J200 533,300 -74,289 -12.23 36,334 -21.28 0.0568
2026-02-12 2025-12-31 13F PTC THERAPEUTICS COM 69366J200 607,589 -319,711 -34.48 46,152 -18.90 0.0716
2025-11-13 2025-09-30 13F PTC THERAPEUTICS COM 69366J200 927,300 -36,000 -3.74 56,908 20.96 0.0751
2025-08-13 2025-06-30 13F PTC THERAPEUTICS COM 69366J200 963,300 293,100 43.73 47,048 37.75 0.0626
2025-05-14 2025-03-31 13F PTC THERAPEUTICS COM 69366J200 670,200 17,100 2.62 34,153 15.85 0.0517
2025-02-13 2024-12-31 13F PTC THERAPEUTICS COM 69366J200 653,100 114,900 21.35 29,481 47.64 0.0436
2024-11-13 2024-09-30 13F PTC THERAPEUTICS COM 69366J200 538,200 -279,900 -34.21 19,967 -20.19 0.0300
2024-08-09 2024-06-30 13F PTC THERAPEUTICS COM 69366J200 818,100 56,700 7.45 25,017 113,613.64 0.0424
2024-05-13 2024-03-31 13F PTC THERAPEUTICS COM 69366J200 761,400 138,500 22.23 22 29.41 0.0348
2024-02-13 2023-12-31 13F PTC THERAPEUTICS COM 69366J200 622,900 388,300 165.52 17 240.00 0.0266
2023-11-14 2023-09-30 13F PTC THERAPEUTICS COM 69366J200 234,600 234,600 5 0.0090
2023-02-13 2022-12-31 13F PTC THERAPEUTICS COM 69366J200 0 -5,600 -100.00 0 -100.00
2022-11-14 2022-09-30 13F PTC THERAPEUTICS COM 69366J200 5,600 5,600 281 0.0004
2022-05-13 2022-03-31 13F PTC THERAPEUTICS COM 69366J200 0 -22,000 -100.00 0 -100.00
2022-02-11 2021-12-31 13F PTC THERAPEUTICS COM 69366J200 22,000 -59,600 -73.04 876 -71.15 0.0011
2021-11-12 2021-09-30 13F PTC THERAPEUTICS COM 69366J200 81,600 -123,410 -60.20 3,036 -64.97 0.0039
2021-08-13 2021-06-30 13F PTC THERAPEUTICS COM 69366J200 205,010 13,810 7.22 8,666 -4.27 0.0108
2021-05-13 2021-03-31 13F PTC THERAPEUTICS COM 69366J200 191,200 191,200 9,053 0.0113
2020-11-13 2020-09-30 13F PTC THERAPEUTICS COM 69366J200 0 -5,200 -100.00 0 -100.00
2020-08-13 2020-06-30 13F PTC THERAPEUTICS COM 69366J200 5,200 -374,200 -98.63 264 -98.44 0.0002
2020-05-14 2020-03-31 13F PTC THERAPEUTICS COM 69366J200 379,400 65,500 20.87 16,925 12.26 0.0164
2020-02-13 2019-12-31 13F PTC THERAPEUTICS COM 69366J200 313,900 183,600 140.91 15,077 242.11 0.0116
2019-11-13 2019-09-30 13F PTC THERAPEUTICS COM 69366J200 130,300 -238,760 -64.69 4,407 -73.46 0.0037
2019-08-12 2019-06-30 13F PTC THERAPEUTICS COM 69366J200 369,060 -538,240 -59.32 16,608 -51.37 0.0146
2019-05-14 2019-03-31 13F PTC THERAPEUTICS COM 69366J200 907,300 -115,400 -11.28 34,151 -2.70 0.0310
2019-02-12 2018-12-31 13F PTC THERAPEUTICS COM 69366J200 1,022,700 740,100 261.89 35,099 164.26 0.0384
2018-11-13 2018-09-30 13F PTC THERAPEUTICS COM 69366J200 282,600 63,400 28.92 13,282 123.90 0.0137
2018-08-13 2018-06-30 13F PTC THERAPEUTICS COM 69366J200 219,200 0 0.00 5,932 0.00 0.0065
2018-05-14 2018-03-31 13F PTC THERAPEUTICS COM 69366J200 219,200 -7,400 -3.27 5,932 56.93 0.0065
2018-02-13 2017-12-31 13F PTC THERAPEUTICS COM 69366J200 226,600 226,600 3,780 0.0042
2017-02-13 2016-12-31 13F PTC THERAPEUTICS COM 69366J200 0 -552,700 -100.00 0 -100.00
2016-11-14 2016-09-30 13F PTC THERAPEUTICS COM 69366J200 552,700 450,800 442.39 7,743 982.94 0.0137
2016-08-12 2016-06-30 13F PTC THERAPEUTICS COM 69366J200 101,900 -846,800 -89.26 715 -88.30 0.0014
2016-05-13 2016-03-31 13F PTC THERAPEUTICS COM 69366J200 948,700 948,700 0.00 6,110 0.0116
2016-02-11 2015-12-31 13F PTC THERAPEUTICS COM 69366J200 0 -65,900 -100.00 0 -100.00
2015-11-12 2015-09-30 13F PTC THERAPEUTICS COM 69366J200 65,900 65,900 0.00 1,760 0.0042
2014-11-12 2014-09-30 13F PTC THERAPEUTICS COM 69366J200 0 -21,600 -100.00 0 -100.00
2014-08-13 2014-06-30 13F PTC THERAPEUTICS COM 69366J200 21,600 21,600 565 0.0013
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.