Lexeo Therapeutics, Inc.
US ˙ NasdaqGM ˙ US52886X1072

SecurityLXEO / Lexeo Therapeutics, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership3,568,242 shares
Latest Disclosed Value $ 20,481,709
State Street Corp reports 11.94% increase in ownership of LXEO / Lexeo Therapeutics, Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 3,568,242 shares of Lexeo Therapeutics, Inc. (US:LXEO) valued at $20,481,709 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 3,187,722 shares of Lexeo Therapeutics, Inc.. This represents a change in shares of 11.94% during the quarter. The current value of the position is $17,056,197 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F LEXEO THERAPEUTICS COM 52886X107 3,568,242 380,520 11.94 20,482 -35.30 0.0007
2026-02-13 2025-12-31 13F LEXEO THERAPEUTICS COM 52886X107 3,187,722 2,642,877 485.07 31,654 775.15 0.0011
2025-11-14 2025-09-30 13F LEXEO THERAPEUTICS COM 52886X107 544,845 31,819 6.20 3,618 75.41 0.0001
2025-08-14 2025-06-30 13F LEXEO THERAPEUTICS COM 52886X107 513,026 43,298 9.22 2,062 26.58 0.0001
2025-05-15 2025-03-31 13F LEXEO THERAPEUTICS COM 52886X107 469,728 12,325 2.69 1,630 -45.86 0.0001
2025-02-14 2024-12-31 13F LEXEO THERAPEUTICS COM 52886X107 457,403 203,457 80.12 3,010 31.11 0.0001
2024-11-14 2024-09-30 13F LEXEO THERAPEUTICS COM 52886X107 253,946 57,674 29.38 2,296 -27.10 0.0001
2024-08-14 2024-06-30 13F LEXEO THERAPEUTICS COM 52886X107 196,272 84,057 74.91 3,148 78.97 0.0001
2024-05-15 2024-03-31 13F LEXEO THERAPEUTICS COM 52886X107 112,215 112,215 1,760 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.