아미쿠스 테라퓨틱스(Amicus Therapeutics)
US ˙ NasdaqGM ˙ US03152W1099
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SecurityFOLD / Amicus Therapeutics, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership1,872,893 shares
Latest Disclosed Value $ 27,082,033
Renaissance Technologies Llc reports 54.57% increase in ownership of FOLD / Amicus Therapeutics, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 1,872,893 shares of Amicus Therapeutics, Inc. (US:FOLD) valued at $27,082,033 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 1,211,693 shares of Amicus Therapeutics, Inc.. This represents a change in shares of 54.57% during the quarter. The current value of the position is $27,138,220 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F AMICUS THERAPEUTIC COM 03152W109 1,872,893 661,200 54.57 27,082 56.96 0.0424
2026-02-12 2025-12-31 13F AMICUS THERAPEUTICS COM 03152W109 1,211,693 -731,478 -37.64 17,255 12.68 0.0268
2025-11-13 2025-09-30 13F AMICUS THERAPEUTICS COM 03152W109 1,943,171 -70,422 -3.50 15,312 32.72 0.0202
2025-08-13 2025-06-30 13F AMICUS THERAPEUTICS COM 03152W109 2,013,593 451,600 28.91 11,538 -9.48 0.0153
2025-05-14 2025-03-31 13F AMICUS THERAPEUTICS COM 03152W109 1,561,993 -546,623 -25.92 12,746 -35.84 0.0193
2025-02-13 2024-12-31 13F AMICUS THERAPEUTICS COM 03152W109 2,108,616 1,339,316 174.10 19,863 141.76 0.0294
2024-11-13 2024-09-30 13F AMICUS THERAPEUTICS COM 03152W109 769,300 137,276 21.72 8,216 31.06 0.0124
2024-08-09 2024-06-30 13F AMICUS THERAPEUTICS COM 03152W109 632,024 -324,176 -33.90 6,270 56,890.91 0.0106
2024-05-13 2024-03-31 13F AMICUS THERAPEUTICS COM 03152W109 956,200 878,800 1,135.40 11 1,000.00 0.0177
2024-02-13 2023-12-31 13F AMICUS THERAPEUTICS COM 03152W109 77,400 -71,000 -47.84 1 0.00 0.0017
2023-11-14 2023-09-30 13F AMICUS THERAPEUTICS COM 03152W109 148,400 148,400 2 0.0031
2023-08-11 2023-06-30 13F AMICUS THERAPEUTICS COM 03152W109 0 -389,000 -100.00 0 -100.00
2023-05-12 2023-03-31 13F AMICUS THERAPEUTICS COM 03152W109 389,000 389,000 4 0.0057
2023-02-13 2022-12-31 13F AMICUS THERAPEUTICS COM 03152W109 0 -284,800 -100.00 0 -100.00
2022-11-14 2022-09-30 13F AMICUS THERAPEUTICS COM 03152W109 284,800 284,800 2,973 0.0042
2020-05-14 2020-03-31 13F AMICUS THERAPEUTICS COM 03152W109 0 -129,854 -100.00 0 -100.00
2020-02-13 2019-12-31 13F AMICUS THERAPEUTICS COM 03152W109 129,854 -1,340,946 -91.17 1,265 -89.28 0.0010
2019-11-13 2019-09-30 13F AMICUS THERAPEUTICS COM 03152W109 1,470,800 1,217,000 479.51 11,796 272.47 0.0100
2019-08-12 2019-06-30 13F AMICUS THERAPEUTICS COM 03152W109 253,800 253,800 3,167 0.0028
2017-02-13 2016-12-31 13F AMICUS THERAPEUTICS COM 03152W109 0 -196,400 -100.00 0 -100.00
2016-11-14 2016-09-30 13F AMICUS THERAPEUTICS COM 03152W109 196,400 196,400 0.00 1,453 0.0026
2016-02-11 2015-12-31 13F AMICUS THERAPEUTICS COM 03152W109 0 0 0 0.0000
2015-05-13 2015-03-31 13F AMICUS THERAPEUTICS COM 03152W109 0 -508,700 -100.00 0 -100.00
2015-02-13 2014-12-31 13F AMICUS THERAPEUTICS COM 03152W109 508,700 378,300 290.11 4,232 445.36 0.0102
2014-11-12 2014-09-30 13F AMICUS THERAPEUTICS COM 03152W109 130,400 9,400 7.77 776 210.40 0.0021
2014-05-14 2014-03-31 13F AMICUS THERAPEUTICS COM 03152W109 121,000 -278,401 -69.70 250 -73.38 0.0006
2014-02-14 2013-12-31 13F AMICUS THERAPEUTICS COM 03152W109 399,401 96,801 31.99 939 33.76 0.0022
2013-11-13 2013-09-30 13F AMICUS THERAPEUTICS COM 03152W109 302,600 128,956 74.26 702 73.33 0.0017
2013-08-12 2013-06-30 13F AMICUS THERAPEUTICS COM 03152W109 173,644 173,644 405 0.0011
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.