큐 바이오파마, Inc.

SecurityCUE / Cue Biopharma, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership213,828 shares
Latest Disclosed Value $ 49,159
Renaissance Technologies Llc reports 10.29% decrease in ownership of CUE / Cue Biopharma, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 213,828 shares of Cue Biopharma, Inc. (US:CUE) valued at $49,159 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 238,354 shares of Cue Biopharma, Inc.. This represents a change in shares of -10.29% during the quarter. The current value of the position is $6,299,373 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F CUE BIOPHARMA COM 22978P106 213,828 -24,526 -10.29 49 -31.94 0.0001
2026-02-12 2025-12-31 13F CUE BIOPHARMA COM 22978P106 238,354 11,290 4.97 73 -55.83 0.0001
2025-11-13 2025-09-30 13F CUE BIOPHARMA COM 22978P106 227,064 93,600 70.13 163 79.12 0.0002
2025-08-13 2025-06-30 13F CUE BIOPHARMA COM 22978P106 133,464 96,518 261.24 91 175.76 0.0001
2025-05-14 2025-03-31 13F CUE BIOPHARMA COM 22978P106 36,946 36,946 34 0.0001
2024-08-09 2024-06-30 13F CUE BIOPHARMA COM 22978P106 0 -274,033 -100.00 0 0.0000
2024-05-13 2024-03-31 13F CUE BIOPHARMA COM 22978P106 274,033 186,833 214.26 1 0.0008
2024-02-13 2023-12-31 13F CUE BIOPHARMA COM 22978P106 87,200 27,400 45.82 0 0.0004
2023-11-14 2023-09-30 13F CUE BIOPHARMA COM 22978P106 59,800 -95,200 -61.42 0 0.0002
2023-08-11 2023-06-30 13F CUE BIOPHARMA COM 22978P106 155,000 103,900 203.33 1 0.0008
2023-05-12 2023-03-31 13F CUE BIOPHARMA COM 22978P106 51,100 -90,600 -63.94 0 0.0002
2023-02-13 2022-12-31 13F CUE BIOPHARMA COM 22978P106 141,700 -284,447 -66.75 0 -100.00 0.0006
2022-11-14 2022-09-30 13F CUE BIOPHARMA COM 22978P106 426,147 -153,553 -26.49 950 -34.16 0.0013
2022-08-12 2022-06-30 13F CUE BIOPHARMA COM 22978P106 579,700 60,400 11.63 1,443 -43.05 0.0017
2022-05-13 2022-03-31 13F CUE BIOPHARMA COM 22978P106 519,300 414,700 396.46 2,534 114.20 0.0030
2022-02-11 2021-12-31 13F CUE BIOPHARMA COM 22978P106 104,600 104,600 1,183 0.0015
2021-05-13 2021-03-31 13F CUE BIOPHARMA COM 22978P106 0 -68,300 -100.00 0 -100.00
2021-02-10 2020-12-31 13F CUE BIOPHARMA COM 22978P106 68,300 -55,196 -44.69 854 -54.06 0.0009
2020-11-13 2020-09-30 13F CUE BIOPHARMA COM 22978P106 123,496 22,496 22.27 1,859 -24.92 0.0019
2020-08-13 2020-06-30 13F CUE BIOPHARMA COM 22978P106 101,000 20,607 25.63 2,476 117.00 0.0021
2020-05-14 2020-03-31 13F CUE BIOPHARMA COM 22978P106 80,393 37,000 85.27 1,141 65.60 0.0011
2020-02-13 2019-12-31 13F CUE BIOPHARMA COM 22978P106 43,393 43,393 689 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.