캐슬 바이오사이언시스, Inc.
US ˙ NasdaqGM ˙ US14843C1053

SecurityCSTL / Castle Biosciences, Inc.
InstitutionInvesco Ltd.
Latest Disclosed Ownership61,012 shares
Latest Disclosed Value $ 1,497,844
Invesco Ltd. reports 54.96% decrease in ownership of CSTL / Castle Biosciences, Inc.

On May 12, 2026 - Invesco Ltd. filed a 13F-HR form disclosing ownership of 61,012 shares of Castle Biosciences, Inc. (US:CSTL) valued at $1,497,845 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 19, 2026 disclosing 135,461 shares of Castle Biosciences, Inc.. This represents a change in shares of -54.96% during the quarter. The current value of the position is $1,281,862 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-12 2026-03-31 13F CASTLE BIOSCIENCES COM 14843C105 61,012 -74,449 -54.96 1,498 -71.59 0.0000
2026-02-19 2025-12-31 13F CASTLE BIOSCIENCES COM 14843C105 135,461 79,621 142.59 5,269 314.56 0.0008
2025-11-13 2025-09-30 13F CASTLE BIOSCIENCES COM 14843C105 55,840 15,411 38.12 1,271 54.06 0.0002
2025-08-13 2025-06-30 13F CASTLE BIOSCIENCES COM 14843C105 40,429 8,178 25.36 826 27.91 0.0001
2025-05-12 2025-03-31 13F CASTLE BIOSCIENCES COM 14843C105 32,251 4,717 17.13 646 -12.01 0.0001
2025-02-13 2024-12-31 13F CASTLE BIOSCIENCES COM 14843C105 27,534 616 2.29 734 -4.43 0.0001
2024-11-12 2024-09-30 13F CASTLE BIOSCIENCES COM 14843C105 26,918 -130 -0.48 768 30.44 0.0001
2024-08-13 2024-06-30 13F CASTLE BIOSCIENCES COM 14843C105 27,048 -348 -1.27 589 -2.97 0.0001
2024-05-14 2024-03-31 13F CASTLE BIOSCIENCES COM 14843C105 27,396 -4,760 -14.80 607 -12.55 0.0001
2024-02-13 2023-12-31 13F CASTLE BIOSCIENCES COM 14843C105 32,156 -3,801 -10.57 694 14.17 0.0002
2023-11-13 2023-09-30 13F CASTLE BIOSCIENCES COM 14843C105 35,957 12,238 51.60 607 86.77 0.0002
2023-08-11 2023-06-30 13F CASTLE BIOSCIENCES COM 14843C105 23,719 814 3.55 325 -37.50 0.0001
2023-05-12 2023-03-31 13F CASTLE BIOSCIENCES COM 14843C105 22,905 3,782 19.78 520 15.56 0.0001
2023-02-13 2022-12-31 13F CASTLE BIOSCIENCES COM 14843C105 19,123 -326,856 -94.47 450 -95.01 0.0001
2022-11-14 2022-09-30 13F CASTLE BIOSCIENCES COM 14843C105 345,979 -2,883 -0.83 9,023 17.82 0.0029
2022-08-15 2022-06-30 13F CASTLE BIOSCIENCES COM 14843C105 348,862 -730,170 -67.67 7,658 -84.18 0.0023
2022-05-16 2022-03-31 13F CASTLE BIOSCIENCES COM 14843C105 1,079,032 29,372 2.80 48,405 7.57 0.0123
2022-02-14 2021-12-31 13F CASTLE BIOSCIENCES COM 14843C105 1,049,660 18,002 1.74 45,000 -34.41 0.0108
2021-11-15 2021-09-30 13F CASTLE BIOSCIENCES COM 14843C105 1,031,658 -106,594 -9.36 68,605 -17.81 0.0174
2021-08-17 2021-06-30 13F CASTLE BIOSCIENCES COM 14843C105 1,138,252 111,547 10.86 83,468 18.75 0.0205
2021-05-17 2021-03-31 13F CASTLE BIOSCIENCES COM 14843C105 1,026,705 -92,418 -8.26 70,288 -6.47 0.0188
2021-02-16 2020-12-31 13F CASTLE BIOSCIENCES COM 14843C105 1,119,123 1,035,819 1,243.42 75,149 1,653.36 0.0219
2020-11-16 2020-09-30 13F CASTLE BIOSCIENCES COM 14843C105 83,304 66,367 391.85 4,286 571.79 0.0014
2020-08-14 2020-06-30 13F CASTLE BIOSCIENCES COM 14843C105 16,937 16,937 638 0.0002
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.