알토 뉴로사이언스, Inc.
US ˙ NYSE

SecurityANRO / Alto Neuroscience, Inc.
InstitutionBarclays Plc
Latest Disclosed Ownership30,392 shares
Latest Disclosed Value $ 540,978
Barclays Plc reports 72,261.90% increase in ownership of ANRO / Alto Neuroscience, Inc.

On February 13, 2026 - Barclays Plc filed a 13F-HR form disclosing ownership of 30,392 shares of Alto Neuroscience, Inc. (US:ANRO) valued at $540,978 USD as of December 31, 2025. The entity filed a previous 13F-HR/A on March 31, 2026 disclosing 42 shares of Alto Neuroscience, Inc.. This represents a change in shares of 72,261.90% during the quarter. The current value of the position is $554,958 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F ALTO NEUROSCIENCE COM 02157Q109 30,392 30,350 72,261.90 541 59.76 0.0001
2026-03-31 2025-09-30 13F/A-3 ALTO NEUROSCIENCE COM 02157Q109 42 41 4,100.00 0 0.0000
2026-03-19 2025-09-30 13F/A-2 ALTO NEUROSCIENCE COM 02157Q109 29,599 29,598 339 0.0001
2025-11-12 2025-09-30 13F ALTO NEUROSCIENCE COM 02157Q109 42 41 0 0.0000
2026-02-27 2025-06-30 13F/A-2 ALTO NEUROSCIENCE COM 02157Q109 1 -22,507 -100.00 0 -100.00 0.0000
2025-08-14 2025-06-30 13F/A-1 ALTO NEUROSCIENCE COM 02157Q109 1 -22,507 0 0.0000
2025-08-13 2025-06-30 13F ALTO NEUROSCIENCE COM 02157Q109 1 -22,507 0 0.0000
2026-03-17 2025-03-31 13F/A-1 ALTO NEUROSCIENCE COM 02157Q109 22,508 -17,299 -43.46 49 -71.43 0.0000
2025-05-15 2025-03-31 13F ALTO NEUROSCIENCE COM 02157Q109 22,508 -17,299 0 0.0000
2026-03-19 2024-12-31 13F/A-1 ALTO NEUROSCIENCE COM 02157Q109 39,807 10,208 34.49 168 -50.30 0.0000
2025-02-13 2024-12-31 13F ALTO NEUROSCIENCE COM 02157Q109 39,807 10,208 0 0.0000
2026-03-31 2024-09-30 13F/A-2 ALTO NEUROSCIENCE COM 02157Q109 29,599 26,556 872.69 339 956.25 0.0001
2024-11-19 2024-09-30 13F/A-1 ALTO NEUROSCIENCE COM 02157Q109 29,599 26,556 0 0.0001
2024-11-15 2024-09-30 13F ALTO NEUROSCIENCE COM 02157Q109 29,599 26,556 0 0.0000
2026-03-23 2024-06-30 13F/A-1 ALTO NEUROSCIENCE COM 02157Q109 3,043 -2,861 -48.46 33 -64.44 0.0000
2024-08-14 2024-06-30 13F ALTO NEUROSCIENCE COM 02157Q109 3,043 -2,861 0 0.0000
2026-03-24 2024-03-31 13F/A-1 ALTO NEUROSCIENCE COM 02157Q109 5,904 5,904 91 0.0000
2024-05-15 2024-03-31 13F ALTO NEUROSCIENCE COM 02157Q109 5,904 5,904 0 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.