AC 면역 SA
US ˙ NasdaqGM ˙ CH0329023102

SecurityACIU / AC Immune SA
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership624,367 shares
Latest Disclosed Value $ 1,717,009
Renaissance Technologies Llc reports 6.65% decrease in ownership of ACIU / AC Immune SA

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 624,367 shares of AC Immune SA (US:ACIU) valued at $1,717,009 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 668,867 shares of AC Immune SA. This represents a change in shares of -6.65% during the quarter. The current value of the position is $1,404,826 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F AC IMMUNE SHS H00263105 624,367 -44,500 -6.65 1,717 -18.24 0.0027
2026-02-12 2025-12-31 13F AC IMMUNE SHS H00263105 668,867 -101,552 -13.18 2,100 -5.66 0.0033
2025-11-13 2025-09-30 13F AC IMMUNE SHS H00263105 770,419 -57,902 -6.99 2,227 32.42 0.0029
2025-08-13 2025-06-30 13F AC IMMUNE SHS H00263105 828,321 24,852 3.09 1,681 11.92 0.0022
2025-05-14 2025-03-31 13F AC IMMUNE SHS H00263105 803,469 63,271 8.55 1,502 -24.82 0.0023
2025-02-13 2024-12-31 13F AC IMMUNE SHS H00263105 740,198 94,191 14.58 1,999 -18.15 0.0030
2024-11-13 2024-09-30 13F AC IMMUNE SHS H00263105 646,007 -6,072 -0.93 2,442 -6.15 0.0037
2024-08-09 2024-06-30 13F AC IMMUNE SHS H00263105 652,079 136,300 26.43 2,602 260,000.00 0.0044
2024-05-13 2024-03-31 13F AC IMMUNE SHS H00263105 515,779 98,200 23.52 2 -50.00 0.0024
2024-02-13 2023-12-31 13F AC IMMUNE SHS H00263105 417,579 -7,600 -1.79 2 100.00 0.0032
2023-11-14 2023-09-30 13F AC IMMUNE SHS H00263105 425,179 7,200 1.72 1 0.00 0.0021
2023-08-11 2023-06-30 13F AC IMMUNE SHS H00263105 417,979 6,900 1.68 1 0.0018
2023-05-12 2023-03-31 13F AC IMMUNE SHS H00263105 411,079 6,400 1.58 1 0.0013
2023-02-13 2022-12-31 13F AC IMMUNE SHS H00263105 404,679 -30,200 -6.94 1 -100.00 0.0011
2022-11-14 2022-09-30 13F AC IMMUNE SHS H00263105 434,879 -39,711 -8.37 1,374 -19.79 0.0019
2022-08-12 2022-06-30 13F AC IMMUNE SHS H00263105 474,590 22,100 4.88 1,713 -5.36 0.0020
2022-05-13 2022-03-31 13F AC IMMUNE SHS H00263105 452,490 10,300 2.33 1,810 -17.31 0.0021
2022-02-11 2021-12-31 13F AC IMMUNE SHS H00263105 442,190 17,500 4.12 2,189 -23.19 0.0027
2021-11-12 2021-09-30 13F AC IMMUNE SHS H00263105 424,690 -1,500 -0.35 2,850 -15.68 0.0037
2021-08-13 2021-06-30 13F AC IMMUNE SHS H00263105 426,190 -100 -0.02 3,380 4.19 0.0042
2021-05-13 2021-03-31 13F AC IMMUNE SHS H00263105 426,290 -152,270 -26.32 3,244 8.46 0.0040
2021-02-10 2020-12-31 13F AC IMMUNE SHS H00263105 578,560 -71,651 -11.02 2,991 -5.74 0.0032
2020-11-13 2020-09-30 13F AC IMMUNE SHS H00263105 650,211 -135,800 -17.28 3,173 -40.02 0.0032
2020-08-13 2020-06-30 13F AC IMMUNE SHS H00263105 786,011 108,700 16.05 5,290 13.03 0.0046
2020-05-14 2020-03-31 13F AC IMMUNE SHS H00263105 677,311 189,909 38.96 4,680 12.69 0.0045
2020-02-13 2019-12-31 13F AC IMMUNE SHS H00263105 487,402 107,300 28.23 4,153 120.67 0.0032
2019-11-13 2019-09-30 13F AC IMMUNE SHS H00263105 380,102 132,063 53.24 1,882 36.67 0.0016
2019-08-12 2019-06-30 13F AC IMMUNE SHS H00263105 248,039 27,789 12.62 1,377 23.83 0.0012
2019-05-14 2019-03-31 13F AC IMMUNE SHS H00263105 220,250 150,350 215.09 1,112 68.23 0.0010
2019-02-12 2018-12-31 13F AC IMMUNE SHS H00263105 69,900 17,600 33.65 661 58.13 0.0007
2018-11-13 2018-09-30 13F AC IMMUNE SHS H00263105 52,300 29,720 131.62 418 99.05 0.0004
2018-08-13 2018-06-30 13F/A-1 AC IMMUNE SHS H00263105 22,580 -56,945 -71.61 210 -74.45 0.0002
2018-08-13 2018-06-30 13F AC IMMUNE SHS H00263105 79,525 822
2018-05-14 2018-03-31 13F AC IMMUNE SHS H00263105 79,525 68,325 610.04 822 474.83 0.0009
2018-02-13 2017-12-31 13F AC IMMUNE SHS H00263105 11,200 11,200 -85.92 143 -82.60 0.0002
2017-11-13 2017-09-30 13F AC IMMUNE SHS H00263105 0 -20,100 -100.00 0 -100.00
2017-08-11 2017-06-30 13F AC IMMUNE SHS H00263105 20,100 20,100 177 0.0002
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.