아이오니스 파마슈티컬스(Ionis Pharmaceuticals, Inc.)
MX ˙ BMV ˙ US4622221004
SecurityMX:IONS / Ionis Pharmaceuticals, Inc.
InstitutionQuadrant Capital Group Llc
Latest Disclosed Ownership616 shares
Latest Disclosed Value $ 46,256
Quadrant Capital Group Llc ownership in IONS / Ionis Pharmaceuticals, Inc.

On May 13, 2026 - Quadrant Capital Group Llc filed a 13F-HR/A form disclosing ownership of 616 shares of Ionis Pharmaceuticals, Inc. (MX:IONS) valued at $46,256 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 616 shares of Ionis Pharmaceuticals, Inc.. This represents a change in shares of 0.00% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F/A-1 IONIS PHARMACEUTICALS COM 462222100 616 0 0.00 46 -4.17 0.0014
2026-05-11 2026-03-31 13F IONIS PHARMACEUTICALS COM 462222100 616 0 49 0.0369
2026-02-12 2025-12-31 13F IONIS PHARMACEUTICALS COM 462222100 616 0 0.00 49 20.00 0.0015
2025-11-13 2025-09-30 13F IONIS PHARMACEUTICALS COM 462222100 616 616 40 0.0013
2025-08-13 2025-06-30 13F IONIS PHARMACEUTICALS COM 462222100 0 -381 -100.00 0 -100.00
2025-05-13 2025-03-31 13F IONIS PHARMACEUTICALS COM 462222100 381 -705 -64.92 11 -70.27 0.0004
2025-02-13 2024-12-31 13F IONIS PHARMACEUTICALS COM 462222100 1,086 216 24.83 38 8.82 0.0026
2024-11-12 2024-09-30 13F IONIS PHARMACEUTICALS COM 462222100 870 10 1.16 35 -15.00 0.0024
2024-08-12 2024-06-30 13F IONIS PHARMACEUTICALS COM 462222100 860 286 49.83 41 66.67 0.0030
2024-05-15 2024-03-31 13F IONIS PHARMACEUTICALS COM 462222100 574 -97 -14.46 25 -27.27 0.0020
2024-02-08 2023-12-31 13F IONIS PHARMACEUTICALS COM 462222100 671 83 14.12 34 26.92 0.0029
2023-11-14 2023-09-30 13F IONIS PHARMACEUTICALS COM 462222100 588 0 0.00 27 8.33 0.0027
2023-08-10 2023-06-30 13F IONIS PHARMACEUTICALS COM 462222100 588 -2 -0.34 24 14.29 0.0024
2023-05-11 2023-03-31 13F IONIS PHARMACEUTICALS COM 462222100 590 343 138.87 21 133.33 0.0022
2023-02-13 2022-12-31 13F IONIS PHARMACEUTICALS COM 462222100 247 -50 -16.84 9 -30.77 0.0011
2022-11-10 2022-09-30 13F IONIS PHARMACEUTICALS COM 462222100 297 34 12.93 13 30.00 0.0017
2022-08-09 2022-06-30 13F IONIS PHARMACEUTICALS COM 462222100 263 -4 -1.50 10 0.00 0.0013
2022-05-06 2022-03-31 13F IONIS PHARMACEUTICALS COM 462222100 267 -73 -21.47 10 0.00 0.0012
2022-02-01 2021-12-31 13F IONIS PHARMACEUTICALS COM 462222100 340 -126 -27.04 10 -37.50 0.0012
2021-11-12 2021-09-30 13F IONIS PHARMACEUTICALS COM 462222100 466 408 703.45 16 700.00 0.0022
2021-08-09 2021-06-30 13F IONIS PHARMACEUTICALS COM 462222100 58 -207 -78.11 2 -83.33 0.0003
2021-05-12 2021-03-31 13F IONIS PHARMACEUTICALS COM 462222100 265 10 3.92 12 -14.29 0.0019
2021-02-16 2020-12-31 13F IONIS PHARMACEUTICALS COM 462222100 255 139 119.83 14 133.33 0.0026
2020-11-13 2020-09-30 13F IONIS PHARMACEUTICALS COM 462222100 116 75 182.93 6 200.00 0.0013
2020-08-13 2020-06-30 13F IONIS PHARMACEUTICALS COM 462222100 41 -449 -91.63 2 -91.30 0.0004
2020-05-15 2020-03-31 13F Ionis Pharmaceuticals Com 462222100 490 467 2,030.43 23 2,200.00 0.0039
2020-03-19 2019-12-31 13F/A-1 Ionis Pharmaceuticals Com 462222100 23 -195 -89.45 1 -91.67 0.0001
2020-02-03 2019-12-31 13F Ionis Pharmaceuticals Com 462222100 23 -195 1 3.3791
2019-10-24 2019-09-30 13F Ionis Pharmaceuticals COM 462222100 218 195 847.83 12 1,100.00 0.0018
2019-07-24 2019-06-30 13F Ionis Pharmaceuticals COM 462222100 23 -653 -96.60 1 -98.11 0.0002
2019-04-29 2019-03-31 13F Ionis Pharmaceuticals COM 462222100 676 653 2,839.13 53 5,200.00 0.0093
2019-01-17 2018-12-31 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 1 0.00 0.0003
2018-10-29 2018-09-30 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 1 0.0003
2018-08-08 2018-06-30 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 0 -100.00
2018-05-10 2018-03-31 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 1 0.00 0.0004
2018-01-31 2017-12-31 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 1 0.00 0.0004
2017-10-13 2017-09-30 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 1 0.00 0.0004
2017-08-14 2017-06-30 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 1 0.0004
2017-04-10 2017-03-31 13F Ionis Pharmaceuticals COM 462222100 23 0 0.00 0 -100.00
2017-01-11 2016-12-31 13F Ionis Pharmaceuticals COM 462222100 23 23 0.00 1 0.0005
2016-07-28 2016-06-30 13F Ionis Pharmaceuticals COM 462222100 0 -91 -100.00 0 -100.00
2016-04-27 2016-03-31 13F Ionis Pharmaceuticals COM 462222100 91 -88 -49.16 2 -80.00 0.0013
2016-01-28 2015-12-31 13F Ionis Pharmaceuticals COM 462222100 179 77 75.49 10 233.33 0.0069
2015-10-28 2015-09-30 13F Isis Pharmaceuticals COM 464330109 102 0 0.00 3 -40.00 0.0021
2015-08-12 2015-06-30 13F Isis Pharmaceuticals COM 464330109 102 102 5 0.0032
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.