바이오크리스트 파마슈티컬스(BioCryst Pharmaceuticals, Inc.)
MX ˙ BMV ˙ US09058V1035
SecurityMX:BCRX / BioCryst Pharmaceuticals, Inc.
InstitutionNorthern Trust Corp
Latest Disclosed Ownership2,104,725 shares
Latest Disclosed Value $ 20,036,982
Northern Trust Corp reports 13.35% increase in ownership of BCRX / BioCryst Pharmaceuticals, Inc.

On May 14, 2026 - Northern Trust Corp filed a 13F-HR form disclosing ownership of 2,104,725 shares of BioCryst Pharmaceuticals, Inc. (MX:BCRX) valued at $20,036,982 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 1,856,903 shares of BioCryst Pharmaceuticals, Inc.. This represents a change in shares of 13.35% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,104,725 247,822 13.35 20,037 38.34 0.0005
2026-02-17 2025-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,856,903 -35,140 -1.86 14,484 0.86 0.0004
2025-11-14 2025-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,892,043 -21,686 -1.13 14,361 -16.25 0.0004
2025-08-13 2025-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,913,729 -41,529 -2.12 17,147 16.93 0.0024
2025-05-13 2025-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,955,258 -49,653 -2.48 14,664 -2.73 0.0022
2025-02-14 2024-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,004,911 143,986 7.74 15,077 6.60 0.0021
2024-11-13 2024-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,860,925 106,162 6.05 14,143 30.42 0.0023
2024-08-14 2024-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,754,763 -50,412 -2.79 10,844 18.26 0.0018
2024-05-14 2024-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,805,175 -41,591 -2.25 9,170 -17.10 0.0016
2024-02-13 2023-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,846,766 -5,897 -0.32 11,062 -15.66 0.0020
2023-11-13 2023-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,852,663 15,142 0.82 13,117 1.39 0.0025
2023-08-11 2023-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,837,521 74,422 4.22 12,936 -12.02 0.0025
2023-05-15 2023-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,763,099 15,639 0.89 14,704 -26.70 0.0029
2023-02-13 2022-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,747,460 -49,331 -2.75 20,061 -11.39 0.0042
2022-11-14 2022-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,796,791 -20,093 -1.11 22,639 17.77 0.0052
2022-08-12 2022-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,816,884 16,986 0.94 19,223 -34.32 0.0041
2022-05-13 2022-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,799,898 -61,110 -3.28 29,266 13.54 0.0051
2022-02-08 2021-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,861,008 -576,576 -23.65 25,775 -26.42 0.0042
2021-11-15 2021-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,437,584 -22,728 -0.92 35,028 -9.95 0.0062
2021-08-13 2021-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,460,312 508,184 26.03 38,897 95.93 0.0069
2021-05-12 2021-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,952,128 -110,979 -5.38 19,853 29.16 0.0037
2021-02-11 2020-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,063,107 -27,319 -1.31 15,371 114.05 0.0030
2020-11-16 2020-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 2,090,426 162,200 8.41 7,181 -21.84 0.0016
2020-08-14 2020-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,928,226 59,096 3.16 9,187 145.77 0.0022
2020-05-14 2020-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,869,130 38,698 2.11 3,738 -40.81 0.0011
2020-02-14 2019-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,830,432 462,630 33.82 6,315 61.14 0.0014
2019-11-13 2019-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,367,802 4,753 0.35 3,919 -24.12 0.0009
2019-08-13 2019-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,363,049 2,115 0.16 5,165 -53.38 0.0012
2019-05-13 2019-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,360,934 10,318 0.76 11,078 1.64 0.0027
2019-02-12 2018-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,350,616 -3,217 -0.24 10,899 5.51 0.0031
2018-11-14 2018-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,353,833 139,272 11.47 10,330 48.42 0.0025
2018-09-18 2018-06-30 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 1,214,561 25,685 2.16 6,960 22.73 0.0018
2018-08-14 2018-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,220,851 31,975 6,996
2018-05-09 2018-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,188,876 13,044 1.11 5,671 -1.77 0.0015
2018-02-14 2017-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,175,832 164,957 16.32 5,773 8.99 0.0015
2017-11-13 2017-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,010,875 4,035 0.40 5,297 -5.39 0.0014
2017-08-11 2017-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 1,006,840 98,077 10.79 5,599 -26.65 0.0016
2017-05-12 2017-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 908,763 36,243 4.15 7,633 38.20 0.0022
2017-02-13 2016-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 872,520 16,529 1.93 5,523 46.30 0.0017
2016-11-09 2016-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 855,991 -7,934 -0.92 3,775 53.83 0.0012
2016-08-12 2016-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 863,925 31,262 3.75 2,454 1.74 0.0008
2016-08-19 2016-03-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 832,663 -71,123 -7.87 2,412 -74.14 0.0008
2016-05-13 2016-03-31 13F Biocryst Pharmaceu COMM 09058V103 832,663 2,357
2016-02-12 2015-12-31 13F Biocryst Pharmaceu COMM 09058V103 903,786 4,654 0.52 9,327 -9.01 0.0031
2015-11-12 2015-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 899,132 138,087 18.14 10,251 -9.79 0.0034
2015-08-13 2015-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 761,045 -67,893 -8.19 11,363 51.79 0.0077
2015-05-14 2015-03-31 13F Biocryst Pharmaceu COMM 09058V103 828,938 -10,128 -1.21 7,486 -26.62 0.0023
2015-02-12 2014-12-31 13F Biocryst Pharmaceu COM 09058V103 839,066 -2,161 -0.26 10,202 23.99 0.0031
2014-11-13 2014-09-30 13F Biocryst Pharmaceu COMM 09058V103 841,227 603,137 253.32 8,228 171.01 0.0026
2014-08-14 2014-06-30 13F BIOCRYST PHARMACEUTICALS com 09058V103 238,090 123,186 107.21 3,036 149.88 0.0009
2014-05-14 2014-03-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 114,904 -87 -0.08 1,215 39.02 0.0004
2014-02-21 2013-12-31 13F/A-1 BIOCRYST PHARMACEUTICALS COM 09058V103 114,991 11,480 11.09 874 16.07 0.0003
2014-02-12 2013-12-31 13F BIOCRYST PHARMACEUTICALS COM 09058V103 114,991 874
2013-11-13 2013-09-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 103,511 -391,536 -79.09 753 -1.83 0.0003
2013-08-09 2013-06-30 13F BIOCRYST PHARMACEUTICALS COM 09058V103 495,047 495,047 767 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.