| Investor | Ra Capital Management, L.p. |
| Manager | Peter Kolchinsky |
13D/G Filings
This page shows a list of all the recent 13D/G filings made by Ra Capital Management, L.p. . Schedule 13D is commonly referred to as a “beneficial ownership report.” The term "beneficial owner" is defined under SEC rules. It includes any person who directly or indirectly shares voting power or investment power (the power to sell the security).
When a person or group of persons acquires beneficial ownership of more than 5% of a voting class of a company’s equity securities, they are required to file a Schedule 13D within ten days after the purchase. Click the link icon to see the full transaction history.
| Date | Form | Target | Prev Shares |
Current Shares |
Change (Percent) |
Ownership (Percent) |
Change (Percent) |
|
|---|---|---|---|---|---|---|---|---|
| 2026-06-04 | 13G | QTTB / Q32 Bio Inc. | 2,332,457 | |||||
| 2026-06-03 | 13G | EDIT / Editas Medicine, Inc. | 8,889,000 | |||||
| 2026-05-21 | 13G | SANA / Sana Biotechnology, Inc. | 18,750,000 | |||||
| 2026-05-15 | 13G/A | PCVX / Vaxcyte, Inc. | 12,964,491 | 12,974,599 | ||||
| 2026-05-15 | 13G/A | UNCY / Unicycive Therapeutics, Inc. | 2,385,279 | 2,801,082 | ||||
| 2026-05-15 | 13G/A | DNTH / Dianthus Therapeutics, Inc. | 2,611,733 | 2,611,733 | ||||
| 2026-05-15 | 13G/A | IVVD / Invivyd, Inc. | 28,857,208 | 21,342,442 | ||||
| 2026-05-15 | 13G/A | PALI / Palisade Bio, Inc. | 15,746,829 | 17,620,479 | ||||
| 2026-05-15 | 13G/A | RNAM / Avidity Biosciences, Inc. | 8,641,031 | 0 | ||||
| 2026-05-15 | 13G/A | CTNM / Contineum Therapeutics, Inc. | 2,179,711 | 1,296,012 | ||||
| 2026-05-15 | 13G/A | AVTX / Avalo Therapeutics, Inc. | 1,939,065 | 2,455,655 | ||||
| 2026-05-15 | 13G | RNA / Atrium Therapeutics, Inc. | 6,300,408 | 864,102 | ||||
| 2026-05-15 | 13G/A | FDMT / 4D Molecular Therapeutics, Inc. | 5,713,852 | 5,105,622 | ||||
| 2026-05-14 | 13D/A | HOWL / Werewolf Therapeutics, Inc. | 6,681,307 | 6,116,140 | ||||
| 2026-05-13 | 13D/A | ARTV / Artiva Biotherapeutics, Inc. | 9,853,302 | 16,377,468 | ||||
| 2026-05-11 | 13G | COAG / Hemab Therapeutics Holdings, Inc. | 7,729,773 | |||||
| 2026-05-01 | 13G | ALT / Altimmune, Inc. | 13,000,000 | |||||
| 2026-04-29 | 13D/A | CLYM / Climb Bio, Inc. | 17,953,284 | 22,631,401 | ||||
| 2026-04-28 | 13G | PRLD / Prelude Therapeutics Incorporated | 6,477,309 | |||||
| 2026-04-27 | 13G | JATT / JATT II Acquisition Corp. | 500,000 | |||||
| 2026-04-23 | 13D/A | ACRV / Acrivon Therapeutics, Inc. | 8,396,018 | 12,284,906 | ||||
| 2026-04-21 | 13D/A | VOR / Vor Biopharma Inc. | 12,739,024 | 12,896,519 | ||||
| 2026-04-17 | 13D/A | WVE / Wave Life Sciences Ltd. | 34,225,506 | 34,225,506 | ||||
| 2026-04-15 | 13D/A | VOR / Vor Biopharma Inc. | 12,554,642 | 12,739,024 | ||||
| 2026-04-13 | 13G/A | 761CVR042 / CONTRA RESOLUTE FOREST | 1,182,624 | |||||
| 2026-04-10 | 13D/A | VOR / Vor Biopharma Inc. | 12,399,706 | 12,554,642 | ||||
| 2026-04-08 | 13D/A | VOR / Vor Biopharma Inc. | 12,187,524 | 12,399,706 | ||||
| 2026-04-07 | 13G | ACRS / Aclaris Therapeutics, Inc. | 0 | 7,626,705 | ||||
| 2026-04-07 | 13G | OKUR / OnKure Therapeutics, Inc. | 4,038,715 | |||||
| 2026-04-06 | 13G | 9688 / Zai Lab Limited | 57,435,330 | |||||
| 2026-04-02 | 13G | KPTI / Karyopharm Therapeutics Inc. | 2,078,913 | |||||
| 2026-04-01 | 13D/A | VOR / Vor Biopharma Inc. | 9,023,068 | 12,187,524 | ||||
| 2026-03-30 | 13G | XNCR / Xencor, Inc. | 0 | 4,736,739 | ||||
| 2026-03-30 | 13D/A | WVE / Wave Life Sciences Ltd. | 25,453,010 | 34,225,506 | ||||
| 2026-03-23 | 13D/A | ACRV / Acrivon Therapeutics, Inc. | 8,359,102 | 8,396,018 | ||||
| 2026-03-23 | 13D/A | SABS / SAB Biotherapeutics, Inc. | 5,166,424 | 7,311,225 | ||||
| 2026-03-20 | 13G | EQ / Equillium, Inc. | 6,480,209 | |||||
| 2026-03-17 | 13D/A | SLDB / Solid Biosciences Inc. | 9,663,926 | 9,313,756 | ||||
| 2026-03-17 | 13D/A | ABOS / Acumen Pharmaceuticals, Inc. | 15,016,063 | 21,101,669 | ||||
| 2026-03-16 | 13D/A | VOR / Vor Biopharma Inc. | 5,411,521 | 9,023,068 | ||||
| 2026-03-11 | 13D/A | SABS / SAB Biotherapeutics, Inc. | 4,401,500 | 5,166,424 | ||||
| 2026-03-10 | 13D/A | SLDB / Solid Biosciences Inc. | 7,997,510 | 9,663,926 | ||||
| 2026-03-06 | 13D/A | TYRA / Tyra Biosciences, Inc. | 11,899,788 | 12,266,575 | ||||
| 2026-03-02 | 13D/A | BCAX / Bicara Therapeutics Inc. | 6,955,993 | 7,279,739 | ||||
| 2026-02-17 | 13D/A | EVMN / Evommune, Inc. | 3,458,770 | 3,494,638 | ||||
| 2026-02-17 | 13D | SGP / SpyGlass Pharma, Inc. | 8,022,639 | |||||
| 2026-02-17 | 13G/A | UNCY / Unicycive Therapeutics, Inc. | 1,960,230 | 2,385,279 | ||||
| 2026-02-17 | 13G/A | SRZN / Surrozen, Inc. | 867,418 | 871,731 | ||||
| 2026-02-17 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 5,561,359 | 6,666,837 | ||||
| 2026-02-17 | 13G/A | PALI / Palisade Bio, Inc. | 9,935,761 | 15,746,829 | ||||
| 2026-02-17 | 13G/A | MNPR / Monopar Therapeutics Inc. | 742,861 | 667,632 | ||||
| 2026-02-17 | 13G/A | LBRX / LB Pharmaceuticals Inc | 1,675,000 | 2,208,604 | ||||
| 2026-02-17 | 13G/A | LRMR / Larimar Therapeutics, Inc. | 6,045,351 | 0 | ||||
| 2026-02-17 | 13G/A | IVVD / Invivyd, Inc. | 21,338,288 | 28,857,208 | ||||
| 2026-02-17 | 13G/A | FULC / Fulcrum Therapeutics, Inc. | 6,053,960 | 6,649,973 | ||||
| 2026-02-17 | 13G/A | ELDN / Eledon Pharmaceuticals, Inc. | 3,566,338 | 0 | ||||
| 2026-02-17 | 13G/A | DNTH / Dianthus Therapeutics, Inc. | 3,866,733 | 2,611,733 | ||||
| 2026-02-17 | 13G/A | CTNM / Contineum Therapeutics, Inc. | 2,122,000 | 2,179,711 | ||||
| 2026-02-17 | 13G/A | AVTX / Avalo Therapeutics, Inc. | 1,386,167 | 1,939,065 | ||||
| 2026-02-17 | 13G/A | ACLX / Arcellx, Inc. | 2,787,327 | 1,267,156 | ||||
| 2026-02-17 | 13G/A | ACET / Adicet Bio, Inc. | 960,237 | |||||
| 2026-02-17 | 13G/A | FDMT / 4D Molecular Therapeutics, Inc. | 4,564,867 | 5,713,852 | ||||
| 2026-02-09 | 13G | ALXO / ALX Oncology Holdings Inc. | 13,117,106 | |||||
| 2026-02-02 | 13G | HLXC / Helix Acquisition Corp. III | 1,250,000 | |||||
| 2026-01-16 | 13G | IPSC / Century Therapeutics, Inc. | 17,944,649 | |||||
| 2026-01-09 | 13D/A | CDTX / Cidara Therapeutics, Inc. | 3,372,923 | 0 | ||||
| 2026-01-07 | 13G | IRON / Disc Medicine, Inc. | 2,228,924 | |||||
| 2025-12-18 | 13D/A | VOR / Vor Biopharma Inc. | 2,345,277 | 5,411,521 | ||||
| 2025-12-18 | 13G | OVID / Ovid Therapeutics Inc. | 13,259,735 | |||||
| 2025-12-18 | 13G | RZLT / Rezolute, Inc. | 15,302,186 | |||||
| 2025-12-15 | 13D/A | CLYM / Climb Bio, Inc. | 31,459,267 | 17,953,284 | ||||
| 2025-12-15 | 13D/A | WVE / Wave Life Sciences Ltd. | 25,453,010 | 25,453,010 | ||||
| 2025-12-12 | 13D | PCSC / Perceptive Capital Solutions Corp | 750,000 | 750,000 | ||||
| 2025-12-10 | 13G/A | FULC / Fulcrum Therapeutics, Inc. | 10,229,099 | 6,053,960 | ||||
| 2025-12-03 | 13G | BNTC / Benitec Biopharma Inc. | 1,850,000 | |||||
| 2025-11-17 | 13D | EVMN / Evommune, Inc. | 3,458,770 | |||||
| 2025-11-17 | 13D/A | CDTX / Cidara Therapeutics, Inc. | 3,372,923 | 3,372,923 | ||||
| 2025-11-14 | 13D/A | VOR / Vor Biopharma Inc. | 810,671 | 2,345,277 | ||||
| 2025-11-14 | 13G/A | TSHA / Taysha Gene Therapies, Inc. | 25,345,988 | 27,662,481 | ||||
| 2025-11-14 | 13G/A | TRML / Tourmaline Bio, Inc. | 2,538,925 | 0 | ||||
| 2025-11-14 | 13G/A | UNCY / Unicycive Therapeutics, Inc. | 13,285,781 | 1,960,230 | ||||
| 2025-11-14 | 13G/A | RXST / RxSight, Inc. | 3,916,825 | 0 | ||||
| 2025-11-14 | 13G/A | MNPR / Monopar Therapeutics Inc. | 620,116 | 742,861 | ||||
| 2025-11-14 | 13G/A | EWTX / Edgewise Therapeutics, Inc. | 8,909,091 | 10,428,437 | ||||
| 2025-11-14 | 13G/A | DYN / Dyne Therapeutics, Inc. | 9,714,392 | 0 | ||||
| 2025-11-14 | 13G/A | RNAM / Avidity Biosciences, Inc. | 6,300,408 | 8,641,031 | ||||
| 2025-11-14 | 13G/A | DNTH / Dianthus Therapeutics, Inc. | 2,866,733 | 3,866,733 | ||||
| 2025-11-14 | 13G/A | AVTX / Avalo Therapeutics, Inc. | 1,094,407 | 1,386,167 | ||||
| 2025-11-13 | 13D/A | WVE / Wave Life Sciences Ltd. | 25,414,165 | 25,453,010 | ||||
| 2025-11-12 | 13G | BCRX / BioCryst Pharmaceuticals, Inc. | 0 | 15,302,186 | ||||
| 2025-11-10 | 13D/A | CDTX / Cidara Therapeutics, Inc. | 3,365,523 | 3,372,923 | ||||
| 2025-11-07 | 13D/A | SION / Sionna Therapeutics, Inc. | 10,071,712 | |||||
| 2025-11-07 | 13D/A | LENZ / LENZ Therapeutics, Inc. | 4,260,606 | 4,265,106 | ||||
| 2025-11-06 | 13D/A | HOWL / Werewolf Therapeutics, Inc. | 6,746,807 | 6,681,307 | ||||
| 2025-11-03 | 13D/A | ETNB / 89bio, Inc. | 20,013,733 | 0 | ||||
| 2025-10-30 | 13D/A | VOR / Vor Biopharma Inc. | 1,186,500 | 810,671 | ||||
| 2025-10-30 | 13G | RANI / Rani Therapeutics Holdings, Inc. | 9,882,477 | |||||
| 2025-10-27 | 13D/A | VOR / Vor Biopharma Inc. | 1,432,693 | 1,186,500 | ||||
| 2025-10-27 | 13G | LXEO / Lexeo Therapeutics, Inc. | 5,000,000 | |||||
| 2025-10-24 | 13G | CCCC / C4 Therapeutics, Inc. | 0 | 9,441,256 | ||||
| 2025-10-20 | 13D/A | VOR / Vor Biopharma Inc. | 1,988,657 | 1,432,693 | ||||
| 2025-10-16 | 13G | JBIO / Jade Biosciences, Inc. | 1,324,954 | 3,214,969 | ||||
| 2025-10-09 | 13G | PALI / Palisade Bio, Inc. | 9,935,761 | |||||
| 2025-10-03 | 13D | SABS / SAB Biotherapeutics, Inc. | 4,401,500 | |||||
| 2025-10-01 | 13D/A | SPRY / ARS Pharmaceuticals, Inc. | 10,860,977 | 10,940,977 | ||||
| 2025-09-30 | 13D/A | PEPG / PepGen Inc. | 10,695,135 | 20,099,753 | ||||
| 2025-09-19 | 13D/A | VOR / Vor Biopharma Inc. | 1,988,657 | |||||
| 2025-09-19 | 13G | LBRX / LB Pharmaceuticals Inc | 1,675,000 | |||||
| 2025-09-08 | 13D/A | MLYS / Mineralys Therapeutics, Inc. | 6,287,597 | 7,796,433 | ||||
| 2025-08-29 | 13G | IVVD / Invivyd, Inc. | 21,338,288 | |||||
| 2025-08-26 | 13G/A | ADGM / Adagio Medical Holdings, Inc. | 0 | 1,200,000 | ||||
| 2025-08-20 | 13G/A | CRVO / CervoMed Inc. | 0 | 1,026,937 | ||||
| 2025-08-18 | 13G | ASMB / Assembly Biosciences, Inc. | 628,092 | 1,530,615 | ||||
| 2025-08-14 | 13G/A | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 6,011,112 | 593,670 | ||||
| 2025-08-14 | 13G/A | URGN / UroGen Pharma Ltd. | 3,206,271 | 0 | ||||
| 2025-08-14 | 13G/A | TSHA / Taysha Gene Therapies, Inc. | 21,539,465 | 25,345,988 | ||||
| 2025-08-14 | 13G/A | STRO / Sutro Biopharma, Inc. | 4,434,637 | 0 | ||||
| 2025-08-14 | 13G/A | SERA / Sera Prognostics, Inc. | 3,032,808 | 0 | ||||
| 2025-08-14 | 13D/A | SLDB / Solid Biosciences Inc. | 7,997,510 | |||||
| 2025-08-14 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 6,084,412 | 5,561,359 | ||||
| 2025-08-14 | 13G/A | TARA / Protara Therapeutics, Inc. | 3,431,713 | 1,971,765 | ||||
| 2025-08-14 | 13G/A | GHRS / GH Research PLC | 6,944,648 | 7,676,697 | ||||
| 2025-08-14 | 13G/A | DAWN / Day One Biopharmaceuticals, Inc. | 5,755,577 | 0 | ||||
| 2025-08-14 | 13G/A | CRVO / CervoMed Inc. | 916,063 | 0 | ||||
| 2025-08-14 | 13G/A | BOLD / Boundless Bio, Inc. | 2,180,631 | 0 | ||||
| 2025-08-14 | 13G/A | ATXS / Astria Therapeutics, Inc. | 5,105,213 | 0 | ||||
| 2025-08-14 | 13G/A | ALEC / Alector, Inc. | 9,695,228 | 0 | ||||
| 2025-08-14 | 13G/A | ADGM / Adagio Medical Holdings, Inc. | 1,200,000 | 0 | ||||
| 2025-08-11 | 13D/A | CDTX / Cidara Therapeutics, Inc. | 3,365,523 | 3,365,523 | ||||
| 2025-07-25 | 13G | CTNM / Contineum Therapeutics, Inc. | 2,122,000 | |||||
| 2025-06-30 | 13D/A | CDTX / Cidara Therapeutics, Inc. | 1,092,796 | 3,365,523 | ||||
| 2025-06-27 | 13D/A | VOR / Vor Biopharma Inc. | 39,709,850 | 39,739,850 | ||||
| 2025-06-06 | 13D/A | TYRA / Tyra Biosciences, Inc. | 10,684,890 | 11,899,788 | ||||
| 2025-05-19 | 13D/A | ITOS / iTeos Therapeutics, Inc. | 4,163,276 | 2,134,806 | ||||
| 2025-05-15 | 13G/A | KURA / Kura Oncology, Inc. | 4,368,998 | 4,004,610 | ||||
| 2025-05-15 | 13G/A | NAMS / NewAmsterdam Pharma Company N.V. | 10,875,454 | 11,063,125 | ||||
| 2025-05-15 | 13G/A | GHRS / GH Research PLC | 6,686,689 | 6,944,648 | ||||
| 2025-05-15 | 13G/A | UNCY / Unicycive Therapeutics, Inc. | 11,520,120 | 13,285,781 | ||||
| 2025-05-15 | 13G/A | GERN / Geron Corporation | 63,319,553 | 63,988,106 | ||||
| 2025-05-15 | 13G/A | DYN / Dyne Therapeutics, Inc. | 6,381,144 | 9,714,392 | ||||
| 2025-05-15 | 13G/A | DNTH / Dianthus Therapeutics, Inc. | 2,866,733 | 2,866,733 | ||||
| 2025-05-15 | 13G/A | SRZN / Surrozen, Inc. | 323,662 | 867,418 | ||||
| 2025-05-15 | 13G/A | CMRX / Chimerix, Inc. | 8,800,000 | 0 | ||||
| 2025-05-15 | 13G/A | CCCC / C4 Therapeutics, Inc. | 4,878,000 | 0 | ||||
| 2025-05-15 | 13G/A | URGN / UroGen Pharma Ltd. | 3,206,271 | 3,206,271 | ||||
| 2025-05-15 | 13G/A | DRUG / Bright Minds Biosciences Inc. | 460,829 | 206,427 | ||||
| 2025-05-15 | 13G/A | PCVX / Vaxcyte, Inc. | 12,649,728 | 12,964,491 | ||||
| 2025-05-15 | 13G/A | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 7,777,942 | 6,011,112 | ||||
| 2025-05-15 | 13G/A | AVTX / Avalo Therapeutics, Inc. | 967,299 | 1,094,407 | ||||
| 2025-05-15 | 13G/A | ADGM / Adagio Medical Holdings, Inc. | 1,613,220 | 1,200,000 | ||||
| 2025-05-14 | 13D/A | ITOS / iTeos Therapeutics, Inc. | 3,659,046 | 4,163,276 | ||||
| 2025-05-14 | 13D/A | HOWL / Werewolf Therapeutics, Inc. | 6,192,881 | 6,746,807 | ||||
| 2025-05-09 | 13D/A | LENZ / LENZ Therapeutics, Inc. | 4,250,856 | 4,260,606 | ||||
| 2025-04-30 | 13D/A | JBIO / Jade Biosciences, Inc. | 1,324,954 | |||||
| 2025-04-04 | 13G | STRO / Sutro Biopharma, Inc. | 4,434,637 | |||||
| 2025-03-31 | 13D/A | ABOS / Acumen Pharmaceuticals, Inc. | 14,981,618 | 15,016,063 | ||||
| 2025-03-31 | 13D/A | TYRA / Tyra Biosciences, Inc. | 10,677,140 | 10,684,890 | ||||
| 2025-03-17 | 13D/A | MLYS / Mineralys Therapeutics, Inc. | 4,949,307 | 6,287,597 | ||||
| 2025-03-10 | 13D/A | JANX / Janux Therapeutics, Inc. | 10,443,181 | 11,971,377 | ||||
| 2025-03-03 | 13D/A | ETNB / 89bio, Inc. | 20,013,733 | 20,013,733 | ||||
| 2025-02-21 | 13D/A | SLDB / Solid Biosciences Inc. | 4,358,478 | |||||
| 2025-02-18 | 13D | SION / Sionna Therapeutics, Inc. | ||||||
| 2025-02-14 | 13G/A | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 8,460,090 | 7,777,942 | ||||
| 2025-02-14 | 13G/A | TNYA / Tenaya Therapeutics, Inc. | 7,980,736 | 0 | ||||
| 2025-02-14 | 13G/A | UNCY / Unicycive Therapeutics, Inc. | 10,472,375 | 11,520,120 | ||||
| 2025-02-14 | 13G/A | RXRX / Recursion Pharmaceuticals, Inc. | 15,384,615 | 7,725,096 | ||||
| 2025-02-14 | 13G/A | NAMS / NewAmsterdam Pharma Company N.V. | 9,095,589 | 10,875,454 | ||||
| 2025-02-14 | 13G/A | TARA / Protara Therapeutics, Inc. | 2,073,075 | 3,431,713 | ||||
| 2025-02-14 | 13G/A | MGNX / MacroGenics, Inc. | 4,053,077 | 0 | ||||
| 2025-02-14 | 13G/A | GLYC / GlycoMimetics, Inc. | 6,383,000 | 0 | ||||
| 2025-02-14 | 13G/A | LBPH / Longboard Pharmaceuticals, Inc. | 3,073,119 | 0 | ||||
| 2025-02-14 | 13G/A | EYPT / EyePoint, Inc. | 3,095,136 | 3,181,818 | ||||
| 2025-02-14 | 13G/A | EVH / Evolent Health, Inc. | 8,279,103 | 3,577,197 | ||||
| 2025-02-14 | 13G/A | 0 | ||||||
| 2025-02-14 | 13G/A | DNTH / Dianthus Therapeutics, Inc. | 2,995,023 | 2,866,733 | ||||
| 2025-02-14 | 13G/A | ADGM / Adagio Medical Holdings, Inc. | 1,337,813 | 1,613,220 | ||||
| 2025-02-14 | 13G/A | DAWN / Day One Biopharmaceuticals, Inc. | 7,809,852 | 5,755,577 | ||||
| 2025-02-14 | 13G/A | FDMT / 4D Molecular Therapeutics, Inc. | 5,098,211 | 4,564,867 | ||||
| 2025-02-14 | 13G/A | 58,139,535 | 0 | |||||
| 2025-02-14 | 13G/A | CTKB / Cytek Biosciences, Inc. | 6,809,404 | 0 | ||||
| 2025-02-14 | 13G/A | CRVO / CervoMed Inc. | 825,373 | 916,063 | ||||
| 2025-02-14 | 13G/A | BIOA / BioAge Labs, Inc. | 2,210,589 | 1,310,589 | ||||
| 2025-02-14 | 13G/A | ANTX / AN2 Therapeutics, Inc. | 1,999,997 | 0 | ||||
| 2025-02-14 | 13G/A | ANRO / Alto Neuroscience, Inc. | 2,075,154 | 0 | ||||
| 2025-02-14 | 13G/A | MNPR / Monopar Therapeutics Inc. | 511,207 | 620,116 | ||||
| 2025-02-14 | 13G/A | ZURA / Zura Bio Limited | 3,217,503 | 3,217,503 | ||||
| 2025-02-03 | 13D/A | ETNB / 89bio, Inc. | 14,254,298 | 20,013,733 | ||||
| 2024-12-30 | 13D/A | VOR / Vor Biopharma Inc. | 22,780,343 | 39,709,850 | ||||
| 2024-12-06 | 13G | ALEC / Alector, Inc. | 9,695,228 | |||||
| 2024-12-05 | 13G | KURA / Kura Oncology, Inc. | 4,368,998 | |||||
| 2024-11-26 | 13D/A | CDTX / Cidara Therapeutics, Inc. | 703,080 | 1,092,796 | ||||
| 2024-11-22 | 13G | ACLX / Arcellx, Inc. | 2,787,327 | |||||
| 2024-11-18 | 13D/A | ETNB / 89bio, Inc. | 14,254,298 | 14,254,298 | ||||
| 2024-11-15 | 13G/A | FDMT / 4D Molecular Therapeutics, Inc. | 5,202,145 | 5,098,211 | ||||
| 2024-11-14 | 13G/A | PCVX / Vaxcyte, Inc. | 9,685,079 | 12,649,728 | ||||
| 2024-11-14 | 13G/A | ELVN / Enliven Therapeutics, Inc. | 1,061,233 | |||||
| 2024-11-14 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 5,330,412 | 6,084,412 | ||||
| 2024-11-14 | 13G/A | APGE / Apogee Therapeutics, Inc. | 1,977,901 | 1,961,863 | ||||
| 2024-11-14 | 13G/A | RNA / Atrium Therapeutics, Inc. | 4,895,959 | 6,300,408 | ||||
| 2024-11-14 | 13G/A | ACET / Adicet Bio, Inc. | 7,696,949 | 8,308,532 | ||||
| 2024-11-14 | 13G/A | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 7,503,976 | 8,460,090 | ||||
| 2024-11-14 | 13G/A | ANRO / Alto Neuroscience, Inc. | 1,385,491 | 2,075,154 | ||||
| 2024-11-14 | 13G/A | GHRS / GH Research PLC | 5,587,333 | 6,686,689 | ||||
| 2024-11-14 | 13G/A | GERN / Geron Corporation | 55,145,502 | 63,319,553 | ||||
| 2024-11-14 | 13G/A | RXST / RxSight, Inc. | 3,404,285 | 3,916,825 | ||||
| 2024-11-14 | 13G/A | ATXS / Astria Therapeutics, Inc. | 4,413,150 | 5,105,213 | ||||
| 2024-11-14 | 13G/A | CELC / Celcuity Inc. | 1,286,960 | 1,286,960 | ||||
| 2024-11-14 | 13G/A | SERA / Sera Prognostics, Inc. | 2,047,221 | 3,032,808 | ||||
| 2024-11-14 | 13G/A | FDMT / 4D Molecular Therapeutics, Inc. | 4,163,211 | 5,202,145 | ||||
| 2024-11-14 | 13G/A | URGN / UroGen Pharma Ltd. | 3,083,558 | 3,206,271 | ||||
| 2024-11-14 | 13G/A | RGLS / Regulus Therapeutics Inc. | 6,250,000 | 766,834 | ||||
| 2024-11-14 | 13G/A | PRAX / Praxis Precision Medicines, Inc. | 1,235,599 | 761,955 | ||||
| 2024-11-14 | 13G/A | ASND / Ascendis Pharma A/S | 10,107,400 | 9,710,428 | ||||
| 2024-11-14 | 13G/A | TSHA / Taysha Gene Therapies, Inc. | 18,670,089 | 21,539,465 | ||||
| 2024-11-14 | 13G/A | BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock) | 2,253,000 | 2,253,000 | ||||
| 2024-11-14 | 13G/A | UNCY / Unicycive Therapeutics, Inc. | 3,472,106 | 10,472,375 | ||||
| 2024-11-14 | 13G/A | TRML / Tourmaline Bio, Inc. | 2,045,028 | 2,538,925 | ||||
| 2024-11-14 | 13G/A | DYN / Dyne Therapeutics, Inc. | 5,213,661 | 6,381,144 | ||||
| 2024-11-14 | 13G/A | TNYA / Tenaya Therapeutics, Inc. | 6,948,236 | 7,980,736 | ||||
| 2024-11-14 | 13G/A | GPCR / Structure Therapeutics Inc. - Depositary Receipt (Common Stock) | 7,225,311 | 5,690,316 | ||||
| 2024-11-14 | 13G/A | THRD / Third Harmonic Bio, Inc. | 2,033,056 | 1,280,826 | ||||
| 2024-11-14 | 13G/A | NAMS / NewAmsterdam Pharma Company N.V. | 8,197,333 | 9,095,589 | ||||
| 2024-11-13 | 13D/A | TYRA / Tyra Biosciences, Inc. | 10,091,071 | 10,677,140 | ||||
| 2024-11-12 | 13G | DRUG / Bright Minds Biosciences Inc. | 460,829 | |||||
| 2024-11-06 | 13G | GLYC / GlycoMimetics, Inc. | 6,383,000 | |||||
| 2024-11-06 | 13G | ENSC / Ensysce Biosciences, Inc. | 1,476,000 | |||||
| 2024-11-05 | 13G | ELDN / Eledon Pharmaceuticals, Inc. | 3,566,338 | |||||
| 2024-11-04 | 13D | SEPN / Septerna, Inc. | 6,995,858 | |||||
| 2024-10-31 | 13G | MNPR / Monopar Therapeutics Inc. | 511,207 | |||||
| 2024-10-22 | 13D/A | TYRA / Tyra Biosciences, Inc. | 10,475,489 | 10,091,071 | ||||
| 2024-10-22 | 13D/A | JANX / Janux Therapeutics, Inc. | 10,742,993 | 10,443,181 | ||||
| 2024-10-07 | 13G | BIOA / BioAge Labs, Inc. | 2,210,589 | |||||
| 2024-10-01 | 13D/A | WVE / Wave Life Sciences Ltd. | 17,269,811 | 25,414,165 | ||||
| 2024-09-23 | 13D | BCAX / Bicara Therapeutics Inc. | 6,955,993 | |||||
| 2024-09-16 | 13D/A | JANX / Janux Therapeutics, Inc. | 10,593,395 | 10,742,993 | ||||
| 2024-09-16 | 13G/A | FULC / Fulcrum Therapeutics, Inc. | 5,544,216 | 10,229,099 | ||||
| 2024-09-03 | 13D/A | ARTV / Artiva Biotherapeutics, Inc. | 9,853,302 | 9,853,302 | ||||
| 2024-08-23 | 13G | AVTX / Avalo Therapeutics, Inc. | 967,299 | |||||
| 2024-08-23 | 13G/A | FULC / Fulcrum Therapeutics, Inc. | 11,609,704 | 5,544,216 | ||||
| 2024-08-13 | 13G/A | ANTX / AN2 Therapeutics, Inc. | 5,551,295 | 1,999,997 | ||||
| 2024-08-12 | 13G | ADGM / Adagio Medical Holdings, Inc. | 1,337,813 | |||||
| 2024-08-07 | 13D/A | ETNB / 89bio, Inc. | 14,254,298 | 14,254,298 | ||||
| 2024-07-29 | 13D | ARTV / Artiva Biotherapeutics, Inc. | 9,853,302 | |||||
| 2024-07-25 | 13D | CDTX / Cidara Therapeutics, Inc. | 0 | 703,080 | ||||
| 2024-07-08 | 13G | RXRX / Recursion Pharmaceuticals, Inc. | 15,384,615 | |||||
| 2024-07-01 | 13G | PRAX / Praxis Precision Medicines, Inc. | 1,235,599 | |||||
| 2024-07-01 | 13D/A | CLYM / Climb Bio, Inc. | 13,190,849 | 31,459,267 | ||||
| 2024-06-24 | 13G | PCSC / Perceptive Capital Solutions Corp | 750,000 | |||||
| 2024-06-20 | 13D/A | AVTE / Aerovate Therapeutics, Inc. | 8,313,982 | 9,242,092 | ||||
| 2024-06-17 | 13G | EVH / Evolent Health, Inc. | 8,279,103 | |||||
| 2024-06-12 | 13D/A | SLDB / Solid Biosciences Inc. | 4,348,828 | 4,358,478 | ||||
| 2024-06-07 | 13G | BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock) | 2,253,000 | |||||
| 2024-06-06 | 13D/A | CLYM / Climb Bio, Inc. | 13,190,292 | 13,190,849 | ||||
| 2024-06-03 | 13G | TRML / Tourmaline Bio, Inc. | 0 | 2,045,028 | ||||
| 2024-05-30 | 13G | GPCR / Structure Therapeutics Inc. - Depositary Receipt (Common Stock) | 7,225,311 | |||||
| 2024-05-17 | 13D/A | CLYM / Climb Bio, Inc. | 13,189,736 | 13,190,292 | ||||
| 2024-05-14 | 13D/A | ITOS / iTeos Therapeutics, Inc. | 4,417,259 | 3,659,046 | ||||
| 2024-05-10 | 13G | MDNAF / Medicenna Therapeutics Corp. | 7,714,760 | |||||
| 2024-05-09 | 13D/A | BDTX / Black Diamond Therapeutics, Inc. | 2,589,904 | 2,788,028 | ||||
| 2024-05-07 | 13D/A | HOWL / Werewolf Therapeutics, Inc. | 6,179,035 | 6,192,881 | ||||
| 2024-05-06 | 13G | RNA / Atrium Therapeutics, Inc. | 2,454,533 | 4,895,959 | ||||
| 2024-05-02 | 13G | ZURA / Zura Bio Limited | 3,217,503 | |||||
| 2024-04-30 | 13D/A | AVTE / Aerovate Therapeutics, Inc. | 8,293,148 | 8,313,982 | ||||
| 2024-04-25 | 13G | TARA / Protara Therapeutics, Inc. | 1,679,205 | 2,073,075 | ||||
| 2024-04-15 | 13G | SRZN / Surrozen, Inc. | 323,662 | |||||
| 2024-04-12 | 13D/A | CLYM / Climb Bio, Inc. | 13,179,181 | 13,189,736 | ||||
| 2024-04-12 | 13G | BOLD / Boundless Bio, Inc. | 2,180,631 | |||||
| 2024-04-11 | 13G | CRVO / CervoMed Inc. | 825,373 | |||||
| 2024-04-11 | 13D/A | ACRV / Acrivon Therapeutics, Inc. | 4,817,359 | 8,359,102 | ||||
| 2024-04-04 | 13G | DYN / Dyne Therapeutics, Inc. | 0 | 5,213,661 | ||||
| 2024-04-01 | 13G | SERA / Sera Prognostics, Inc. | 2,047,221 | |||||
| 2024-03-29 | 13D/A | NKTX / Nkarta, Inc. | 7,832,340 | 13,848,371 | ||||
| 2024-03-29 | 13D/A | SPRY / ARS Pharmaceuticals, Inc. | 9,459,678 | 10,860,977 | ||||
| 2024-03-29 | 13G | ANRO / Alto Neuroscience, Inc. | 1,385,491 | |||||
| 2024-03-28 | 13D | LENZ / LENZ Therapeutics, Inc. | 4,250,856 | |||||
| 2024-03-25 | 13G | RGLS / Regulus Therapeutics Inc. | 0 | 6,250,000 | ||||
| 2024-03-25 | 13G | CYBN / Cybin Inc. | 58,139,535 | |||||
| 2024-03-18 | 13D/A | CLYM / Climb Bio, Inc. | 13,176,403 | 13,179,181 | ||||
| 2024-03-11 | 13D/A | PEPG / PepGen Inc. | 10,695,135 | 10,695,135 | ||||
| 2024-03-06 | 13D/A | JANX / Janux Therapeutics, Inc. | 8,670,644 | 10,593,395 | ||||
| 2024-03-06 | 13D/A | ETNB / 89bio, Inc. | 12,875,855 | 14,254,298 | ||||
| 2024-02-27 | 13D/A | CNTB / Connect Biopharma Holdings Limited | 3,062,871 | 0 | ||||
| 2024-02-26 | 13G | LRMR / Larimar Therapeutics, Inc. | 0 | 6,045,351 | ||||
| 2024-02-22 | 13G | CTKB / Cytek Biosciences, Inc. | 6,809,404 | 6,809,404 | ||||
| 2024-02-21 | 13D/A | ICVX / Icosavax, Inc. | 5,985,843 | 0 | ||||
| 2024-02-14 | 13G/A | EYPT / EyePoint, Inc. | 3,408,706 | 3,095,136 | ||||
| 2024-02-14 | 13G/A | UNCY / Unicycive Therapeutics, Inc. | 3,470,689 | 3,472,106 | ||||
| 2024-02-14 | 13G/A | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 0 | |||||
| 2024-02-14 | 13D/A | HOWL / Werewolf Therapeutics, Inc. | 6,159,054 | 6,179,035 | ||||
| 2024-02-14 | 13G/A | TRML / Tourmaline Bio, Inc. | 0 | |||||
| 2024-02-14 | 13G/A | NKTR / Nektar Therapeutics | 18,700,000 | 0 | ||||
| 2024-02-14 | 13G/A | CMRX / Chimerix, Inc. | 6,501,624 | 8,800,000 | ||||
| 2024-02-14 | 13G/A | FDMT / 4D Molecular Therapeutics, Inc. | 2,789,721 | 4,163,211 | ||||
| 2024-02-14 | 13G/A | IMGN / ImmunoGen, Inc. | 22,075,158 | 26,916,027 | ||||
| 2024-02-14 | 13G/A | HLVX / HilleVax, Inc. | 1,760,019 | 0 | ||||
| 2024-02-14 | 13G/A | ACRS / Aclaris Therapeutics, Inc. | 4,398,453 | 0 | ||||
| 2024-02-14 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 5,516,067 | 5,330,412 | ||||
| 2024-02-14 | 13G/A | NSTGQ / NS Wind Down Co., Inc. | 2,577,373 | 0 | ||||
| 2024-02-14 | 13G/A | COGT / Cogent Biosciences, Inc. | 5,999,481 | 0 | ||||
| 2024-02-14 | 13G/A | URGN / UroGen Pharma Ltd. | 3,083,550 | 3,083,558 | ||||
| 2024-02-14 | 13G/A | NAMS / NewAmsterdam Pharma Company N.V. | 9,333,333 | 8,197,333 | ||||
| 2024-02-14 | 13G/A | MGNX / MacroGenics, Inc. | 3,764,871 | 4,053,077 | ||||
| 2024-02-14 | 13G/A | HARP / Harpoon Therapeutics, Inc. | 1,701,570 | 1,712,792 | ||||
| 2024-02-14 | 13G/A | RXST / RxSight, Inc. | 3,052,796 | 3,404,285 | ||||
| 2024-02-14 | 13G/A | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 7,691,990 | 7,503,976 | ||||
| 2024-02-14 | 13G/A | TNYA / Tenaya Therapeutics, Inc. | 6,428,483 | 6,948,236 | ||||
| 2024-02-14 | 13G/A | CELC / Celcuity Inc. | 2,249,421 | 1,286,960 | ||||
| 2024-02-14 | 13G/A | TSHA / Taysha Gene Therapies, Inc. | 18,690,868 | 18,670,089 | ||||
| 2024-02-14 | 13G | APGE / Apogee Therapeutics, Inc. | 1,977,901 | |||||
| 2024-02-14 | 13G/A | PCVX / Vaxcyte, Inc. | 8,153,559 | 9,685,079 | ||||
| 2024-02-14 | 13G/A | INBX.V / Inhibrx, Inc. | 3,853,867 | 4,724,352 | ||||
| 2024-02-14 | 13G/A | ALPN / Alpine Immune Sciences, Inc. | 4,397,368 | 5,903,234 | ||||
| 2024-02-14 | 13G/A | GERN / Geron Corporation | 48,423,211 | 55,145,502 | ||||
| 2024-02-14 | 13G/A | RNA / Atrium Therapeutics, Inc. | 5,454,533 | 2,454,533 | ||||
| 2024-02-14 | 13G/A | FULC / Fulcrum Therapeutics, Inc. | 9,686,628 | 11,609,704 | ||||
| 2024-02-14 | 13G/A | DAWN / Day One Biopharmaceuticals, Inc. | 7,040,622 | 7,809,852 | ||||
| 2024-02-14 | 13G/A | ASND / Ascendis Pharma A/S | 9,967,172 | 10,107,400 | ||||
| 2024-02-14 | 13G/A | GHRS / GH Research PLC | 5,561,118 | 5,587,333 | ||||
| 2024-02-14 | 13G/A | GRCL / Gracell Biotechnologies Inc. - Depositary Receipt (Common Stock) | 48,600,300 | 48,600,221 | ||||
| 2024-02-14 | 13G/A | CVAC / CureVac N.V. | 2,744,270 | |||||
| 2024-02-14 | 13G/A | ANTX / AN2 Therapeutics, Inc. | 3,773,517 | 5,551,295 | ||||
| 2024-02-13 | 13D/A | PEPG / PepGen Inc. | 8,131,952 | 10,695,135 | ||||
| 2024-02-12 | 13D/A | MLYS / Mineralys Therapeutics, Inc. | 3,180,920 | 4,949,307 | ||||
| 2024-02-12 | 13G | CRBP / Corbus Pharmaceuticals Holdings, Inc. | 430,182 | |||||
| 2024-02-12 | 13G | ATXS / Astria Therapeutics, Inc. | 0 | 4,413,150 | ||||
| 2024-02-06 | 13D/A | TYRA / Tyra Biosciences, Inc. | 7,236,454 | 10,475,489 | ||||
| 2024-02-05 | 13G | ACET / Adicet Bio, Inc. | 0 | 7,696,949 | ||||
| 2024-02-02 | 13G | DNTH / Dianthus Therapeutics, Inc. | 2,995,023 | 2,995,023 | ||||
| 2024-01-29 | 13G | EWTX / Edgewise Therapeutics, Inc. | 0 | 8,909,091 | ||||
| 2024-01-19 | 13G | VXRT / Vaxart, Inc. | 15,384,615 | |||||
| 2024-01-12 | 13G | LBPH / Longboard Pharmaceuticals, Inc. | 3,073,119 | |||||
| 2024-01-11 | 13D/A | SLDB / Solid Biosciences Inc. | 3,431,618 | 4,348,828 | ||||
| 2023-12-29 | 13G | URGN / UroGen Pharma Ltd. | 3,083,550 | |||||
| 2023-12-26 | 13G | CCCC / C4 Therapeutics, Inc. | 4,878,000 | |||||
| 2023-12-20 | 13D/A | CNTB / Connect Biopharma Holdings Limited | 5,124,309 | 3,062,871 | ||||
| 2023-12-14 | 13D/A | CNTB / Connect Biopharma Holdings Limited | 5,955,011 | 5,124,309 | ||||
| 2023-12-13 | 13D/A | ETNB / 89bio, Inc. | 12,874,814 | 12,875,855 | ||||
| 2023-12-04 | 13D/A | CNTB / Connect Biopharma Holdings Limited | 6,991,003 | 5,955,011 | ||||
| 2023-11-27 | 13G | THRD / Third Harmonic Bio, Inc. | 534,687 | 2,033,056 | ||||
| 2023-11-17 | 13D/A | CLYM / Climb Bio, Inc. | 13,163,071 | 13,176,403 | ||||
| 2023-11-14 | 13G/A | DSGN / Design Therapeutics, Inc. | 2,971,231 | 0 | ||||
| 2023-11-06 | 13G | HARP / Harpoon Therapeutics, Inc. | 1,701,570 | |||||
| 2023-10-30 | 13G | MGNX / MacroGenics, Inc. | 0 | 3,764,871 | ||||
| 2023-10-05 | 13G | SLNO / Soleno Therapeutics, Inc. | 1,233,300 | |||||
| 2023-09-29 | 13G | CMRX / Chimerix, Inc. | 6,501,624 | |||||
| 2023-09-25 | 13D/A | SPRY / ARS Pharmaceuticals, Inc. | 6,759,678 | 9,459,678 | ||||
| 2023-09-22 | 13G | CBAY / CymaBay Therapeutics, Inc. | 6,940,000 | |||||
| 2023-09-19 | 13D/A | CTKB / Cytek Biosciences, Inc. | 13,139,327 | 6,809,404 | ||||
| 2023-08-31 | 13D | SPRY / ARS Pharmaceuticals, Inc. | 1,742,186 | 6,759,678 | ||||
| 2023-08-25 | 13G | TSHA / Taysha Gene Therapies, Inc. | 18,690,868 | |||||
| 2023-08-21 | 13G | GRCL / Gracell Biotechnologies Inc. - Depositary Receipt (Common Stock) | 48,600,300 | |||||
| 2023-08-17 | 13G | NKTR / Nektar Therapeutics | 18,700,000 | |||||
| 2023-08-14 | 13G/A | BLU / BluEnergies Ltd. | 12,452,574 | 0 | ||||
| 2023-08-14 | 13G/A | KNTE / Kinnate Biopharma Inc. | 4,264,144 | 0 | ||||
| 2023-08-11 | 13D/A | VOR / Vor Biopharma Inc. | 22,760,145 | 22,780,343 | ||||
| 2023-08-11 | 13D/A | ETNB / 89bio, Inc. | 12,876,898 | 12,874,814 | ||||
| 2023-08-09 | 13D/A | DICE / DICE Therapeutics Inc | 7,877,862 | 0 | ||||
| 2023-08-01 | 13G/A | NAMS / NewAmsterdam Pharma Company N.V. | 9,333,333 | |||||
| 2023-07-25 | 13D/A | ABOS / Acumen Pharmaceuticals, Inc. | 9,774,551 | 14,981,618 | ||||
| 2023-07-06 | 13G | TALS / Talaris Therapeutics Inc | 2,333,175 | |||||
| 2023-07-06 | 13G | UNCY / Unicycive Therapeutics, Inc. | 3,470,689 | |||||
| 2023-06-27 | 13D/A | AVTE / Aerovate Therapeutics, Inc. | 8,263,982 | 8,293,148 | ||||
| 2023-06-21 | 13D/A | DICE / DICE Therapeutics Inc | 7,660,615 | 7,877,862 | ||||
| 2023-06-12 | 13D/A | STSA / Satsuma Pharmaceuticals Inc | 5,944,252 | 0 | ||||
| 2023-06-05 | 13G | FDMT / 4D Molecular Therapeutics, Inc. | 2,789,721 | |||||
| 2023-05-30 | 13D/A | ICVX / Icosavax, Inc. | 5,779,347 | 5,985,843 | ||||
| 2023-05-15 | 13G/A | DALS / DA32 Life Science Tech Acquisition Corp - Class A | 1,500,000 | 0 | ||||
| 2023-05-15 | 13G/A | TVTX / Travere Therapeutics, Inc. | 3,984,681 | 0 | ||||
| 2023-05-15 | 13G/A | ARYE / ARYA Sciences Acquisition Corp V - Class A | 1,000,000 | 0 | ||||
| 2023-04-18 | 13D/A | STSA / Satsuma Pharmaceuticals Inc | 5,944,252 | |||||
| 2023-04-10 | 13G | NSTGQ / NS Wind Down Co., Inc. | 143,900 | 2,577,373 | ||||
| 2023-04-10 | 13D/A | CLYM / Climb Bio, Inc. | 13,151,959 | 13,163,071 | ||||
| 2023-04-10 | 13G/A | ASND / Ascendis Pharma A/S | 6,957,179 | 9,967,172 | ||||
| 2023-03-30 | 13G/A | GHRS / GH Research PLC | 4,898,373 | 5,561,118 | ||||
| 2023-03-30 | 13D/A | ACRV / Acrivon Therapeutics, Inc. | 4,813,442 | 4,817,359 | ||||
| 2023-03-30 | 13D/A | ETNB / 89bio, Inc. | 9,376,402 | 12,876,898 | ||||
| 2023-03-29 | 13D/A | DICE / DICE Therapeutics Inc | 6,848,911 | 7,660,615 | ||||
| 2023-03-27 | 13G | CVAC / CureVac N.V. | 12,245,955 | |||||
| 2023-03-20 | 13G | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 0 | 18,564,300 | ||||
| 2023-02-27 | 13G/A | IMRA / Bitwise Funds Trust - Bitwise MARA Option Income Strategy ETF | 3,250,724 | 2,122,465 | ||||
| 2023-02-24 | 13D | MLYS / Mineralys Therapeutics, Inc. | 3,180,920 | |||||
| 2023-02-14 | 13G/A | EYPT / EyePoint, Inc. | 1,606,859 | 3,408,706 | ||||
| 2023-02-14 | 13G/A | INBX.V / Inhibrx, Inc. | 3,185,831 | 3,853,867 | ||||
| 2023-02-14 | 13G/A | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 48,778,172 | 7,691,990 | ||||
| 2023-02-14 | 13G/A | IOBT / IO Biotech, Inc. | 1,857,755 | 1,127,260 | ||||
| 2023-02-14 | 13G/A | BLU / Bellus Health Inc | 10,230,274 | 12,452,574 | ||||
| 2023-02-14 | 13G/A | PYXS / Pyxis Oncology, Inc. | 2,282,173 | 0 | ||||
| 2023-02-14 | 13G/A | COGT / Cogent Biosciences, Inc. | 3,588,081 | 5,999,481 | ||||
| 2023-02-14 | 13G/A | MIST / Milestone Pharmaceuticals Inc. | 2,246,503 | 0 | ||||
| 2023-02-14 | 13G/A | PCVX / Vaxcyte, Inc. | 3,865,808 | 8,153,559 | ||||
| 2023-02-14 | 13G/A | ENTX / Entera Bio Ltd. | 2,353,000 | 295,966 | ||||
| 2023-02-14 | 13G/A | DAWN / Day One Biopharmaceuticals, Inc. | 4,965,588 | 7,040,622 | ||||
| 2023-02-14 | 13G/A | ACET / Adicet Bio, Inc. | 2,364,351 | 0 | ||||
| 2023-02-14 | 13G/A | IMRA / Bitwise Funds Trust - Bitwise MARA Option Income Strategy ETF | 3,220,825 | 3,250,724 | ||||
| 2023-02-14 | 13G/A | CELC / Celcuity Inc. | 1,486,471 | 2,249,421 | ||||
| 2023-02-14 | 13G/A | GHRS / GH Research PLC | 2,843,757 | 4,898,373 | ||||
| 2023-02-14 | 13G/A | KNTE / Kinnate Biopharma Inc. | 3,593,052 | 4,264,144 | ||||
| 2023-02-14 | 13G/A | ASND / Ascendis Pharma A/S | 7,567,900 | 6,957,179 | ||||
| 2023-02-14 | 13G/A | THRD / Third Harmonic Bio, Inc. | 534,687 | |||||
| 2023-02-14 | 13G/A | PHASQ / PhaseBio Pharmaceuticals, Inc. | 2,850,000 | 0 | ||||
| 2023-02-14 | 13G/A | NSTGQ / NS Wind Down Co., Inc. | 3,517,694 | 143,900 | ||||
| 2023-02-14 | 13G/A | ALPN / Alpine Immune Sciences, Inc. | 4,356,632 | 4,397,368 | ||||
| 2023-02-14 | 13G | OBIO / Orchestra BioMed Holdings, Inc. | 610,283 | |||||
| 2023-02-14 | 13G/A | VERA / Vera Therapeutics, Inc. | 2,000,000 | 0 | ||||
| 2023-02-14 | 13G/A | BLSA / BCLS Acquisition Corp - Class A | 1,250,000 | 0 | ||||
| 2023-02-14 | 13G | HLVX / HilleVax, Inc. | 1,760,019 | |||||
| 2023-02-14 | 13G/A | ANTX / AN2 Therapeutics, Inc. | 3,666,663 | 3,773,517 | ||||
| 2023-02-14 | 13G/A | GERN / Geron Corporation | 32,388,799 | 48,423,211 | ||||
| 2023-02-14 | 13G/A | TVTX / Travere Therapeutics, Inc. | 5,614,428 | 3,984,681 | ||||
| 2023-02-14 | 13G/A | RLMD / Relmada Therapeutics, Inc. | 2,000,000 | 0 | ||||
| 2023-02-14 | 13G/A | SYBX / Synlogic, Inc. | 6,666,666 | 0 | ||||
| 2023-02-14 | 13G/A | MGTA / Magenta Therapeutics Inc | 3,588,081 | 0 | ||||
| 2023-02-14 | 13G/A | PRDS / Pardes Biosciences Inc | 4,431,901 | 0 | ||||
| 2023-02-14 | 13G/A | TIL / Instil Bio, Inc. | 7,670,793 | 0 | ||||
| 2023-02-14 | 13G/A | FVAM / 5:01 Acquisition Corp. | 750,000 | 0 | ||||
| 2023-02-14 | 13G/A | TNYA / Tenaya Therapeutics, Inc. | 3,551,508 | 6,428,483 | ||||
| 2023-02-14 | 13G/A | IMGN / ImmunoGen, Inc. | 22,162,958 | 22,075,158 | ||||
| 2023-02-14 | 13G/A | CNCE / Concert Pharmaceuticals Inc | 3,510,103 | 5,199,746 | ||||
| 2023-02-14 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 4,871,067 | 5,516,067 | ||||
| 2023-01-10 | 13D/A | HOWL / Werewolf Therapeutics, Inc. | 4,304,447 | 6,159,054 | ||||
| 2023-01-06 | 13G/A | FULC / Fulcrum Therapeutics, Inc. | 7,000,000 | 9,686,628 | ||||
| 2022-12-30 | 13D/A | ACHL / Achilles Therapeutics plc - Depositary Receipt (Common Stock) | 2,976,943 | 1,607,834 | ||||
| 2022-12-30 | 13G | RNA / Atrium Therapeutics, Inc. | 5,454,533 | |||||
| 2022-12-23 | 13D/A | ACHL / Achilles Therapeutics plc - Depositary Receipt (Common Stock) | 4,107,508 | 2,976,943 | ||||
| 2022-12-15 | 13D/A | ACHL / Achilles Therapeutics plc - Depositary Receipt (Common Stock) | 5,014,687 | 4,107,508 | ||||
| 2022-12-09 | 13D/A | VOR / Vor Biopharma Inc. | 11,131,300 | 22,760,145 | ||||
| 2022-12-05 | 13D/A | SLDB / Solid Biosciences Inc. | 12,447,873 | 3,431,618 | ||||
| 2022-12-02 | 13G | NAMS / NewAmsterdam Pharma Company N.V. | 4,333,333 | |||||
| 2022-11-28 | 13D | ACRV / Acrivon Therapeutics, Inc. | 4,813,442 | |||||
| 2022-11-14 | 13D/A | VOR / Vor Biopharma Inc. | 11,120,973 | 11,131,300 | ||||
| 2022-11-14 | 13G/A | / LIANBIO | 7,655,015 | 0 | ||||
| 2022-11-14 | 13G/A | ATXS / Astria Therapeutics, Inc. | 1,262,193 | 0 | ||||
| 2022-11-14 | 13G/A | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 9,694,789 | 0 | ||||
| 2022-11-14 | 13G/A | VERU / Veru Inc. | 7,900,000 | 0 | ||||
| 2022-11-14 | 13G/A | OLMA / Olema Pharmaceuticals, Inc. | 0 | 0 | ||||
| 2022-11-14 | 13G/A | DYN / Dyne Therapeutics, Inc. | 2,805,045 | 0 | ||||
| 2022-11-14 | 13G/A | XLO / Xilio Therapeutics, Inc. | 2,002,217 | 0 | ||||
| 2022-11-14 | 13G/A | OTIC / Otonomy Inc | 5,600,000 | 0 | ||||
| 2022-11-14 | 13G/A | LRMR / Larimar Therapeutics, Inc. | 1,334,610 | 0 | ||||
| 2022-11-14 | 13G/A | LAB / Standard BioTools Inc. | 4,651,177 | 0 | ||||
| 2022-10-24 | 13G | IMRA / Bitwise Funds Trust - Bitwise MARA Option Income Strategy ETF | 3,220,825 | |||||
| 2022-10-21 | 13D/A | ETNB / 89bio, Inc. | 7,806,169 | 9,376,402 | ||||
| 2022-10-19 | 13D/A | DICE / DICE Therapeutics Inc | 5,208,911 | 6,848,911 | ||||
| 2022-10-17 | 13G | INBX.V / Inhibrx, Inc. | 0 | 3,185,831 | ||||
| 2022-10-17 | 13G | ACET / Adicet Bio, Inc. | 2,364,351 | |||||
| 2022-10-14 | 13D/A | FMTX / Forma Therapeutics Holdings Inc | 9,040,309 | 0 | ||||
| 2022-10-13 | 13G | DSGN / Design Therapeutics, Inc. | 2,971,231 | |||||
| 2022-10-04 | 13D/A | SLDB / Solid Biosciences Inc. | 12,447,873 | 12,447,873 | ||||
| 2022-10-03 | 13G | ALPN / Alpine Immune Sciences, Inc. | 4,356,632 | |||||
| 2022-09-27 | 13G/A | MGTA / Magenta Therapeutics Inc | 3,588,081 | |||||
| 2022-09-26 | 13D/A | PNT / POINT Biopharma Global Inc. | 9,003,018 | 0 | ||||
| 2022-09-26 | 13G | COGT / Cogent Biosciences, Inc. | 3,612,207 | 3,588,081 | ||||
| 2022-09-26 | 13G | THRD / Third Harmonic Bio, Inc. | 3,475,687 | |||||
| 2022-09-16 | 13D/A | PNT / POINT Biopharma Global Inc. | 9,003,018 | 9,003,018 | ||||
| 2022-09-06 | 13D/A | SLDB / Solid Biosciences Inc. | 12,367,873 | 12,447,873 | ||||
| 2022-09-06 | 13G | COGT / Cogent Biosciences, Inc. | 3,612,207 | |||||
| 2022-09-02 | 13D/A | FMTX / Forma Therapeutics Holdings Inc | 9,029,184 | 9,040,309 | ||||
| 2022-08-29 | 13D/A | PNT / POINT Biopharma Global Inc. | 8,856,018 | 9,003,018 | ||||
| 2022-08-26 | 13G | FULC / Fulcrum Therapeutics, Inc. | 7,000,000 | |||||
| 2022-08-15 | 13G/A | SCPH / scPharmaceuticals Inc. | 2,691,770 | 0 | ||||
| 2022-08-15 | 13G/A | MGNX / MacroGenics, Inc. | 6,103,594 | 0 | ||||
| 2022-08-15 | 13G/A | KALV / KalVista Pharmaceuticals, Inc. | 1,930,322 | 0 | ||||
| 2022-08-15 | 13G/A | TCRX / TScan Therapeutics, Inc. | 1,255,317 | 0 | ||||
| 2022-08-15 | 13G/A | EWTX / Edgewise Therapeutics, Inc. | 2,613,623 | 0 | ||||
| 2022-08-15 | 13G/A | AKUS / Akouos Inc | 2,281,249 | 0 | ||||
| 2022-08-15 | 13G/A | CYTT / Cyteir Therapeutics, Inc. | 3,350,506 | 0 | ||||
| 2022-08-12 | 13D/A | HOWL / Werewolf Therapeutics, Inc. | 3,968,583 | 4,304,447 | ||||
| 2022-07-06 | 13D/A | ETNB / 89bio, Inc. | 4,291,881 | 7,806,169 | ||||
| 2022-06-23 | 13D/A | PEPG / PepGen Inc. | 8,131,952 | 8,131,952 | ||||
| 2022-06-22 | 13G | TIL / Instil Bio, Inc. | 7,670,793 | |||||
| 2022-06-21 | 13D/A | WVE / Wave Life Sciences Ltd. | 7,828,457 | 17,269,811 | ||||
| 2022-06-03 | 13D/A | KALA / KALA BIO, Inc. | 6,194,789 | 3,412,868 | ||||
| 2022-06-01 | 13D/A | KALA / KALA BIO, Inc. | 8,045,299 | 6,194,789 | ||||
| 2022-05-25 | 13D/A | KALA / KALA BIO, Inc. | 10,914,613 | 8,045,299 | ||||
| 2022-05-25 | 13G | CELC / Celcuity Inc. | 1,486,471 | |||||
| 2022-05-20 | 13D | PEPG / PepGen Inc. | 8,131,952 | |||||
| 2022-05-16 | 13G/A | BOLT / Bolt Biotherapeutics, Inc. | 2,378,325 | 0 | ||||
| 2022-05-16 | 13G/A | OLMA / Olema Pharmaceuticals, Inc. | 2,150,404 | 0 | ||||
| 2022-05-16 | 13G/A | PHAT / Phathom Pharmaceuticals, Inc. | 3,115,008 | 0 | ||||
| 2022-05-16 | 13G/A | ZGNX / Zogenix Inc | 3,333,700 | 0 | ||||
| 2022-05-02 | 13D/A | NKTX / Nkarta, Inc. | 5,605,129 | 7,832,340 | ||||
| 2022-04-28 | 13G | NSTGQ / NS Wind Down Co., Inc. | 3,517,694 | |||||
| 2022-04-25 | 13G | ACRS / Aclaris Therapeutics, Inc. | 0 | 4,398,453 | ||||
| 2022-04-21 | 13G | VERU / Veru Inc. | 7,900,000 | |||||
| 2022-04-08 | 13G | ANTX / AN2 Therapeutics, Inc. | 3,666,663 | |||||
| 2022-04-01 | 13D/A | KALA / KALA BIO, Inc. | 10,961,533 | 10,914,613 | ||||
| 2022-03-24 | 13G | FLDM / Standard BioTools Inc | 4,651,177 | |||||
| 2022-03-14 | 13D/A | CTKB / Cytek Biosciences, Inc. | 11,082,163 | 13,139,327 | ||||
| 2022-02-28 | 13D/A | CTKB / Cytek Biosciences, Inc. | 9,607,028 | 11,082,163 | ||||
| 2022-02-24 | 13G | VERA / Vera Therapeutics, Inc. | 2,000,000 | |||||
| 2022-02-18 | 13G/A | SCPH / scPharmaceuticals Inc. | 6,691,770 | 2,691,770 | ||||
| 2022-02-14 | 13G/A | CCXI / Churchill Capital Corp XI | 4,776,548 | 0 | ||||
| 2022-02-14 | 13G/A | AVIR / Atea Pharmaceuticals, Inc. | 5,368,451 | 0 | ||||
| 2022-02-14 | 13G/A | KNTE / Kinnate Biopharma Inc. | 3,593,052 | 3,593,052 | ||||
| 2022-02-14 | 13G/A | IMGN / ImmunoGen, Inc. | 18,417,458 | 22,162,958 | ||||
| 2022-02-14 | 13G/A | PHAT / Phathom Pharmaceuticals, Inc. | 3,825,008 | 3,115,008 | ||||
| 2022-02-14 | 13G/A | MCRB / Seres Therapeutics, Inc. | 4,702,206 | 0 | ||||
| 2022-02-14 | 13G/A | ZGNX / Zogenix Inc | 5,345,631 | 3,333,700 | ||||
| 2022-02-14 | 13G/A | CNCE / Concert Pharmaceuticals Inc | 1,823,520 | 3,510,103 | ||||
| 2022-02-14 | 13G/A | CYT / Cyteir Therapeutics, Inc. | 3,247,117 | 3,350,506 | ||||
| 2022-02-14 | 13G/A | VRDN / Viridian Therapeutics, Inc. | 388,385 | 0 | ||||
| 2022-02-14 | 13G/A | FVAM / 5:01 Acquisition Corp. | 750,000 | 750,000 | ||||
| 2022-02-14 | 13G/A | SCPH / scPharmaceuticals Inc. | 3,518,998 | 6,691,770 | ||||
| 2022-02-14 | 13G/A | SBTX / Silverback Therapeutics Inc | 1,742,186 | 1,742,186 | ||||
| 2022-02-14 | 13G/A | XLO / Xilio Therapeutics, Inc. | 1,532,767 | 2,002,217 | ||||
| 2022-02-14 | 13G/A | LRMR / Larimar Therapeutics, Inc. | 1,515,151 | 1,334,610 | ||||
| 2022-02-14 | 13G/A | KALV / KalVista Pharmaceuticals, Inc. | 1,399,489 | 1,930,322 | ||||
| 2022-02-14 | 13G/A | MGNX / MacroGenics, Inc. | 4,375,217 | 6,103,594 | ||||
| 2022-02-14 | 13G | EWTX / Edgewise Therapeutics, Inc. | 2,613,623 | |||||
| 2022-02-14 | 13G/A | TNGX / Tango Therapeutics, Inc. | 1,250,000 | 2,250,000 | ||||
| 2022-02-14 | 13G/A | BLSA / BCLS Acquisition Corp - Class A | 1,250,000 | 1,250,000 | ||||
| 2022-02-14 | 13G/A | GHRS / GH Research PLC | 2,978,955 | 2,843,757 | ||||
| 2022-02-14 | 13G/A | OTIC / Otonomy Inc | 3,092,294 | 5,600,000 | ||||
| 2022-02-14 | 13G/A | TVTX / Travere Therapeutics, Inc. | 4,557,867 | 5,614,428 | ||||
| 2022-02-14 | 13G/A | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 41,543,004 | 48,778,172 | ||||
| 2022-02-14 | 13G/A | GERN / Geron Corporation | 31,114,941 | 32,388,799 | ||||
| 2022-02-14 | 13G/A | XFOR / X4 Pharmaceuticals, Inc. | 1,748,021 | 1,136,000 | ||||
| 2022-02-14 | 13G/A | NVAX / Novavax, Inc. | 3,788,564 | 2,097,794 | ||||
| 2022-02-14 | 13G/A | ATXS / Astria Therapeutics, Inc. | 5,745,744 | 1,262,193 | ||||
| 2022-02-14 | 13G/A | MIST / Milestone Pharmaceuticals Inc. | 2,327,714 | 2,246,503 | ||||
| 2022-02-14 | 13G/A | CTMX / CytomX Therapeutics, Inc. | 3,500,000 | 0 | ||||
| 2022-02-14 | 13G/A | AKUS / Akouos Inc | 2,281,249 | 2,281,249 | ||||
| 2022-02-14 | 13G/A | ASND / Ascendis Pharma A/S | 5,865,338 | 7,567,900 | ||||
| 2022-02-14 | 13G/A | OLMA / Olema Pharmaceuticals, Inc. | 2,150,404 | 2,150,404 | ||||
| 2022-02-14 | 13G/A | DYNE / Dyntek Inc | 2,805,045 | 2,805,045 | ||||
| 2022-02-14 | 13G/A | / Nautilus Biotechnology Inc | 2,436,430 | |||||
| 2022-02-14 | 13G/A | FLAC / Frazier Lifesciences Acquisition Corp - Class A | 0 | |||||
| 2022-02-14 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 4,179,067 | 4,871,067 | ||||
| 2022-02-14 | 13G/A | PHAS / PhaseBio Pharmaceuticals Inc | 2,850,000 | 2,850,000 | ||||
| 2022-02-14 | 13G/A | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 12,315,213 | 9,694,789 | ||||
| 2022-02-14 | 13G/A | PYXS / Pyxis Oncology, Inc. | 1,914,934 | 2,282,173 | ||||
| 2022-01-10 | 13G | PRDS / Pardes Biosciences Inc | 4,431,901 | |||||
| 2021-12-22 | 13G | BLU / Bellus Health Inc | 10,230,274 | |||||
| 2021-12-20 | 13G | RLMD / Relmada Therapeutics, Inc. | 0 | 2,000,000 | ||||
| 2021-11-19 | 13G | IOBT / IO Biotech, Inc. | 1,857,755 | |||||
| 2021-11-15 | 13G/A | ARYD / ARYA Sciences Acquisition Corp IV | 1,000,000 | 0 | ||||
| 2021-11-15 | 13G/A | TRIL / Tidal Trust II - Defiance Trillion Dollar Club Index ETF | 5,290,481 | 0 | ||||
| 2021-11-15 | 13G/A | AADI / Aadi Bioscience, Inc. | 2,486,242 | 0 | ||||
| 2021-11-15 | 13G | / LIANBIO | 7,655,015 | |||||
| 2021-11-15 | 13G/A | CRIS / Curis, Inc. | 7,707,790 | 0 | ||||
| 2021-11-15 | 13G/A | HLXA / Helix Acquisition Corp - Class A | 700,000 | 0 | ||||
| 2021-11-15 | 13G/A | INZY / Inozyme Pharma, Inc. | 2,003,653 | 0 | ||||
| 2021-11-15 | 13G/A | ARDX / Ardelyx, Inc. | 6,163,086 | 0 | ||||
| 2021-11-12 | 13D/A | WVE / Wave Life Sciences Ltd. | 7,823,207 | 7,828,457 | ||||
| 2021-11-05 | 13G | XLO / Xilio Therapeutics, Inc. | 1,532,767 | |||||
| 2021-10-28 | 13D/A | FMTX / Forma Therapeutics Holdings Inc | 9,011,651 | 9,029,184 | ||||
| 2021-10-28 | 13D/A | KALA / KALA BIO, Inc. | 10,874,613 | 10,961,533 | ||||
| 2021-10-25 | 13G | OTIC / Otonomy Inc | 3,092,294 | |||||
| 2021-10-25 | 13G | PYXS / Pyxis Oncology, Inc. | 1,914,934 | |||||
| 2021-10-01 | 13G | SYBX / Synlogic, Inc. | 6,666,666 | |||||
| 2021-09-27 | 13D | DICE / DICE Therapeutics Inc | 5,208,911 | |||||
| 2021-09-27 | 13D | TYRA / Tyra Biosciences, Inc. | 7,236,454 | |||||
| 2021-09-14 | 13D/A | PNT / POINT Biopharma Global Inc. | 8,856,018 | 8,856,018 | ||||
| 2021-09-13 | 13D/A | ABOS / Acumen Pharmaceuticals, Inc. | 9,770,773 | 9,774,551 | ||||
| 2021-08-23 | 13G | AADI / Aadi Bioscience, Inc. | 1,574,806 | 2,486,242 | ||||
| 2021-08-19 | 13D | ELYM / Eliem Therapeutics, Inc. | 13,151,959 | |||||
| 2021-08-18 | 13D/A | WVE / Wave Life Sciences Ltd. | 7,775,207 | 7,823,207 | ||||
| 2021-08-16 | 13G | ADVM / Adverum Biotechnologies, Inc. | 9,502,383 | 0 | ||||
| 2021-08-13 | 13G | EYPT / EyePoint, Inc. | 1,606,859 | |||||
| 2021-08-13 | 13G | RXST / RxSight, Inc. | 3,052,796 | |||||
| 2021-08-12 | 13D | ICVX / Icosavax, Inc. | 5,779,347 | |||||
| 2021-08-09 | 13G | DALS / DA32 Life Science Tech Acquisition Corp - Class A | 1,500,000 | |||||
| 2021-08-09 | 13G | TNYA / Tenaya Therapeutics, Inc. | 3,551,508 | |||||
| 2021-08-06 | 13D | / Cytek Biosciences, Inc. | 9,607,028 | |||||
| 2021-07-28 | 13G | TCRX / TScan Therapeutics, Inc. | 1,255,317 | |||||
| 2021-07-23 | 13G | ARYE / ARYA Sciences Acquisition Corp V - Class A | 1,000,000 | |||||
| 2021-07-20 | 13G | PNT / POINT Biopharma Global Inc. | 8,856,018 | |||||
| 2021-07-16 | 13D | ABOS / Acumen Pharmaceuticals, Inc. | 9,770,773 | |||||
| 2021-07-12 | 13D | AVTE / Aerovate Therapeutics, Inc. | 8,263,982 | |||||
| 2021-07-12 | 13G | AADI / Aadi Bioscience, Inc. | 1,574,806 | |||||
| 2021-07-09 | 13G | GHRS / GH Research PLC | 2,978,955 | |||||
| 2021-06-30 | 13G | ENTX / Entera Bio Ltd. | 2,353,000 | |||||
| 2021-06-30 | 13D | / Therapeutics Acquisition Corp. Class A | 1,098,318 | |||||
| 2021-06-29 | 13G | CYT / Cyteir Therapeutics, Inc. | 3,247,117 | |||||
| 2021-06-21 | 13G | NOVN / Novan Inc | 0 | |||||
| 2021-06-16 | 13D | JANX / Janux Therapeutics, Inc. | 8,670,644 | |||||
| 2021-06-16 | 13D/A | ETNB / 89bio, Inc. | 4,965,769 | 4,291,881 | ||||
| 2021-06-15 | 13G | ATXS / Astria Therapeutics, Inc. | 5,745,744 | |||||
| 2021-06-07 | 13D/A | CNTB / Connect Biopharma Holdings Limited | 6,640,417 | 6,991,003 | ||||
| 2021-06-07 | 13G | DAWN / Day One Biopharmaceuticals, Inc. | 4,965,588 | |||||
| 2021-06-04 | 13D/A | ETNB / 89bio, Inc. | 4,736,214 | 4,965,769 | ||||
| 2021-05-27 | 13G | KALV / KalVista Pharmaceuticals, Inc. | 786,270 | 1,399,489 | ||||
| 2021-05-17 | 13G/A | US33830X1046 / Five Prime Therapeutics Inc | 4,285,161 | 0 | ||||
| 2021-05-17 | 13G/A | LYRA / Lyra Therapeutics, Inc. | 815,849 | 0 | ||||
| 2021-05-17 | 13G/A | / Pandion Therapeutics Inc | 1,770,023 | 0 | ||||
| 2021-05-17 | 13G/A | INBX / Inhibrx Biosciences, Inc. | 2,129,003 | 0 | ||||
| 2021-05-06 | 13D | HOWL / Werewolf Therapeutics, Inc. | 3,968,583 | |||||
| 2021-05-05 | 13G | MCRB / Seres Therapeutics, Inc. | 4,702,206 | |||||
| 2021-04-16 | 13D | ACHL / Achilles Therapeutics plc - Depositary Receipt (Common Stock) | 5,014,687 | |||||
| 2021-04-07 | 13G/A | TRIL / Tidal Trust II - Defiance Trillion Dollar Club Index ETF | 5,290,481 | 5,290,481 | ||||
| 2021-04-07 | 13G/A | AVIR / Atea Pharmaceuticals, Inc. | 5,368,451 | 5,368,451 | ||||
| 2021-04-07 | 13G | BOLT / Bolt Biotherapeutics, Inc. | 2,378,325 | |||||
| 2021-03-30 | 13G/A | PCVX / Vaxcyte, Inc. | 3,710,699 | 3,865,808 | ||||
| 2021-03-29 | 13D | CNTB / Connect Biopharma Holdings Limited | 6,640,417 | |||||
| 2021-03-24 | 13G | PHAS / PhaseBio Pharmaceuticals Inc | 2,850,000 | |||||
| 2021-03-23 | 13D/A | SLDB / Solid Biosciences Inc. | 9,976,569 | 12,367,873 | ||||
| 2021-03-15 | 13G/A | VRDN / Viridian Therapeutics, Inc. | 451,932 | 388,385 | ||||
| 2021-03-09 | 13G | ARYD / ARYA Sciences Acquisition Corp IV | 1,000,000 | |||||
| 2021-03-02 | 13D/A | 859319303 / Sterling Financial Corp | 4,681,858 | 5,914,252 | ||||
| 2021-02-19 | 13D | VOR / Vor Biopharma Inc. | 11,120,973 | |||||
| 2021-02-16 | 13G | US33830X1046 / Five Prime Therapeutics Inc | 4,285,161 | |||||
| 2021-02-16 | 13G | LYRA / Lyra Therapeutics, Inc. | 815,849 | |||||
| 2021-02-16 | 13G | NVAX / Novavax, Inc. | 3,241,083 | 3,788,564 | ||||
| 2021-02-16 | 13G/A | ASND / Ascendis Pharma A/S | 5,818,862 | 5,865,338 | ||||
| 2021-02-16 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 5,422,312 | 4,179,067 | ||||
| 2021-02-16 | 13G/A | US74140Y1010 / Prevail Therapeutics Inc. | 3,363,605 | 0 | ||||
| 2021-02-16 | 13G | BLSA / BCLS Acquisition Corp - Class A | 1,250,000 | |||||
| 2021-02-16 | 13G | IMGN / ImmunoGen, Inc. | 18,417,458 | |||||
| 2021-02-16 | 13G | MGNX / MacroGenics, Inc. | 4,375,217 | |||||
| 2021-02-16 | 13G/A | PCVX / Vaxcyte, Inc. | 5,489,181 | 3,710,699 | ||||
| 2021-02-16 | 13G | AVIR / Atea Pharmaceuticals, Inc. | 5,368,451 | |||||
| 2021-02-16 | 13G | AKUS / Akouos Inc | 2,281,249 | |||||
| 2021-02-16 | 13G | CRIS / Curis, Inc. | 7,707,790 | |||||
| 2021-02-16 | 13G | INZY / Inozyme Pharma, Inc. | 2,003,653 | |||||
| 2021-02-16 | 13G | OLMA / Olema Pharmaceuticals, Inc. | 2,150,404 | |||||
| 2021-02-16 | 13G | TRIL / Tidal Trust II - Defiance Trillion Dollar Club Index ETF | 5,290,481 | |||||
| 2021-02-16 | 13G | SBTX / Silverback Therapeutics Inc | 1,742,186 | |||||
| 2021-02-16 | 13G | FVAM / 5:01 Acquisition Corp. | 750,000 | |||||
| 2021-02-16 | 13G/A | CCXI / Churchill Capital Corp XI | 3,199,389 | 4,776,548 | ||||
| 2021-02-16 | 13G/A | SCPH / scPharmaceuticals Inc. | 3,247,005 | 3,518,998 | ||||
| 2021-02-16 | 13G | / Pandion Therapeutics Inc | 1,770,023 | |||||
| 2021-02-16 | 13G | KNTE / Kinnate Biopharma Inc. | 3,593,052 | |||||
| 2021-02-16 | 13G/A | TVTX / Travere Therapeutics, Inc. | 4,252,453 | 4,557,867 | ||||
| 2021-02-16 | 13G | CNCE / Concert Pharmaceuticals Inc | 1,823,520 | |||||
| 2021-02-16 | 13G/A | RLMD / Relmada Therapeutics, Inc. | 761,666 | 0 | ||||
| 2021-02-16 | 13G/A | VSTM / Verastem, Inc. | 9,129,251 | 0 | ||||
| 2021-02-16 | 13G/A | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 10,364,658 | 12,315,213 | ||||
| 2021-02-16 | 13G | GERN / Geron Corporation | 31,114,941 | |||||
| 2021-02-16 | 13G | LRMR / Larimar Therapeutics, Inc. | 1,515,151 | |||||
| 2021-02-16 | 13G/A | ARDX / Ardelyx, Inc. | 5,527,088 | 6,163,086 | ||||
| 2021-02-16 | 13G | ADVM / Adverum Biotechnologies, Inc. | 9,502,383 | |||||
| 2021-02-16 | 13G/A | PHAT / Phathom Pharmaceuticals, Inc. | 3,646,808 | 3,825,008 | ||||
| 2021-02-16 | 13G | HLXA / Helix Acquisition Corp - Class A | 700,000 | |||||
| 2021-02-16 | 13G | INBX / Inhibrx Biosciences, Inc. | 2,129,003 | |||||
| 2021-02-16 | 13G | NAUT / Nautilus Biotechnology, Inc. | 1,000,000 | |||||
| 2021-02-16 | 13G/A | XFOR / X4 Pharmaceuticals, Inc. | 1,648,485 | 1,748,021 | ||||
| 2021-02-16 | 13G | DYNE / Dyntek Inc | 2,805,045 | |||||
| 2021-02-16 | 13G/A | ZGNX / Zogenix Inc | 2,260,751 | 5,345,631 | ||||
| 2021-02-16 | 13G | MIST / Milestone Pharmaceuticals Inc. | 2,327,714 | |||||
| 2021-02-16 | 13G/A | CRNX / Crinetics Pharmaceuticals, Inc. | 1,875,209 | 564,102 | ||||
| 2021-02-16 | 13G | TNGX / Tango Therapeutics, Inc. | 1,250,000 | |||||
| 2021-02-16 | 13G | VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) | 41,543,004 | |||||
| 2021-02-11 | 13G/A | ITRM / Iterum Therapeutics plc | 13,730,376 | 0 | ||||
| 2021-02-10 | 13G/A | TGTX / TG Therapeutics, Inc. | 12,788,457 | 6,361,123 | ||||
| 2021-02-10 | 13G/A | KROS / Keros Therapeutics, Inc. | 0 | |||||
| 2021-02-10 | 13G/A | ARVN / Arvinas, Inc. | 3,672,872 | 0 | ||||
| 2021-02-10 | 13G/A | CRDF / Cardiff Oncology, Inc. | 3,290,000 | 0 | ||||
| 2021-02-10 | 13G/A | TGTX / TG Therapeutics, Inc. | 12,788,457 | 8,685,471 | ||||
| 2021-02-10 | 13G | KROS / Keros Therapeutics, Inc. | 1,875,000 | |||||
| 2021-02-08 | 13G/A | ITRM / Iterum Therapeutics plc | 10,000,000 | 13,730,376 | ||||
| 2021-01-29 | 13G | CTMX / CytomX Therapeutics, Inc. | 3,500,000 | |||||
| 2020-12-17 | 13G | VRDN / Viridian Therapeutics, Inc. | 451,932 | |||||
| 2020-12-16 | 13D/A | SLDB / Solid Biosciences Inc. | 4,571,164 | 9,976,569 | ||||
| 2020-12-02 | 13G | ITRM / Iterum Therapeutics plc | 10,000,000 | |||||
| 2020-10-09 | 13G | CRDF / Cardiff Oncology, Inc. | 3,290,000 | |||||
| 2020-10-07 | 13D/A | US28249H1041 / Eidos Therapeutics, Inc. | 2,162,671 | 1,798,339 | ||||
| 2020-09-21 | 13D/A | ETNB / 89bio, Inc. | 3,436,214 | 4,736,214 | ||||
| 2020-09-10 | 13G/A | ASND / Ascendis Pharma A/S | 4,185,342 | 5,818,862 | ||||
| 2020-08-05 | 13D | ITOS / iTeos Therapeutics, Inc. | 4,417,259 | |||||
| 2020-07-24 | 13D | NKTX / Nkarta, Inc. | 5,605,129 | |||||
| 2020-07-10 | 13D/A | ETNB / 89bio, Inc. | 3,161,214 | 3,436,214 | ||||
| 2020-07-10 | 13G | PCVX / Vaxcyte, Inc. | 5,489,181 | |||||
| 2020-07-10 | 13G/A | VSTM / Verastem, Inc. | 18,604,651 | 9,129,251 | ||||
| 2020-06-25 | 13D | FMTX / Forma Therapeutics Holdings Inc | 9,011,651 | |||||
| 2020-06-10 | 13G/A | TGTX / TG Therapeutics, Inc. | 9,880,323 | 12,788,457 | ||||
| 2020-04-09 | 13G/A | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 6,389,901 | 10,364,658 | ||||
| 2020-03-13 | 13D/A | KALA / KALA BIO, Inc. | 4,537,478 | 10,874,613 | ||||
| 2020-03-05 | 13G | VSTM / Verastem, Inc. | 18,604,651 | |||||
| 2020-02-14 | 13G/A | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 4,845,933 | 6,389,901 | ||||
| 2020-02-14 | 13G/A | BCRX / BioCryst Pharmaceuticals, Inc. | 10,660,349 | 0 | ||||
| 2020-02-14 | 13G | XFOR / X4 Pharmaceuticals, Inc. | 1,648,485 | |||||
| 2020-02-14 | 13G/A | EIGR / Eiger BioPharmaceuticals, Inc. | 2,415,458 | 0 | ||||
| 2020-02-14 | 13G | CCXI / Churchill Capital Corp XI | 3,199,389 | |||||
| 2020-02-14 | 13G/A | TGTX / TG Therapeutics, Inc. | 8,198,337 | 9,880,323 | ||||
| 2020-02-14 | 13G | ARDX / Ardelyx, Inc. | 2,103,530 | 5,527,088 | ||||
| 2020-02-14 | 13G | RLMD / Relmada Therapeutics, Inc. | 761,666 | |||||
| 2020-02-14 | 13G/A | SCPH / scPharmaceuticals Inc. | 2,857,143 | 3,247,005 | ||||
| 2020-02-14 | 13G/A | ARVN / Arvinas, Inc. | 3,672,872 | |||||
| 2020-02-14 | 13G/A | MYOV / Myovant Sciences Ltd | 3,711,549 | 0 | ||||
| 2020-02-14 | 13G/A | PHAT / Phathom Pharmaceuticals, Inc. | 3,646,646 | 3,646,808 | ||||
| 2020-02-14 | 13G/A | ZGNX / Zogenix Inc | 2,382,168 | 2,260,751 | ||||
| 2020-02-14 | 13G | TVTX / Travere Therapeutics, Inc. | 4,252,453 | |||||
| 2020-02-14 | 13G/A | ASND / Ascendis Pharma A/S | 4,240,536 | 4,185,342 | ||||
| 2020-02-14 | 13G | US74140Y1010 / Prevail Therapeutics Inc. | 3,363,605 | |||||
| 2020-02-05 | 13D | BDTX / Black Diamond Therapeutics, Inc. | 2,589,904 | |||||
| 2019-11-13 | 13D | ETNB / 89bio, Inc. | 3,161,214 | |||||
| 2019-11-08 | 13G | PHAT / Phathom Pharmaceuticals, Inc. | 3,646,646 | |||||
| 2019-10-18 | 13G/A | RYTM / Rhythm Pharmaceuticals, Inc. | 1,950,332 | 5,422,312 | ||||
| 2019-10-11 | 13D/A | RARX / Ra Pharmaceuticals, Inc. | 3,851,808 | 4,858,260 | ||||
| 2019-09-17 | 13D | 859319303 / Sterling Financial Corp | 4,681,858 | |||||
| 2019-07-30 | 13D/A | SLDB / Solid Biosciences Inc. | 4,571,164 | |||||
| 2019-07-10 | 13G/A | IFRX / InflaRx N.V. | 2,810,708 | 0 | ||||
| 2019-04-24 | 13D/A | KALV / KalVista Pharmaceuticals, Inc. | 958,570 | 786,270 | ||||
| 2019-04-15 | 13D/A | KALV / KalVista Pharmaceuticals, Inc. | 1,441,070 | 958,570 | ||||
| 2019-04-10 | 13G/A | IFRX / InflaRx N.V. | 2,085,089 | 2,810,708 | ||||
| 2019-02-14 | 13G/A | SPRO / Spero Therapeutics, Inc. | 0 | |||||
| 2019-02-14 | 13G/A | BCRX / BioCryst Pharmaceuticals, Inc. | 9,234,692 | 10,660,349 | ||||
| 2019-02-14 | 13G/A | KDMN / Kadmon Holdings Inc | 80,293,421 | 2,666,666 | ||||
| 2019-02-14 | 13G/A | BHVN / Biohaven Ltd. | 1,997,278 | 0 | ||||
| 2019-02-14 | 13G/A | IFRX / InflaRx N.V. | 1,620,653 | 2,085,089 | ||||
| 2019-02-14 | 13G/A | KRYS / Krystal Biotech, Inc. | 700,000 | 0 | ||||
| 2019-02-14 | 13G | ZGNX / Zogenix Inc | 1,145,268 | 2,382,168 | ||||
| 2019-02-14 | 13G | ORTX / Orchard Therapeutics plc - Depositary Receipt (Common Stock) | 4,845,933 | |||||
| 2019-02-14 | 13G | TGTX / TG Therapeutics, Inc. | 1,004,314 | 8,198,337 | ||||
| 2019-02-14 | 13G | RYTM / Rhythm Pharmaceuticals, Inc. | 1,950,332 | |||||
| 2019-02-14 | 13G | ARVN / Arvinas, Inc. | 3,138,412 | |||||
| 2019-02-14 | 13G | CRNX / Crinetics Pharmaceuticals, Inc. | 1,875,209 | |||||
| 2019-02-14 | 13G | MYOV / Myovant Sciences Ltd | 3,711,549 | |||||
| 2019-02-11 | 13G/A | ASND / Ascendis Pharma A/S | 5,580,690 | 4,240,536 | ||||
| 2019-01-28 | 13D/A | WVE / Wave Life Sciences Ltd. | 7,512,049 | 7,775,207 | ||||
| 2018-11-07 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 3,324,989 | 2,814,589 | ||||
| 2018-11-02 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 3,324,989 | 3,324,989 | ||||
| 2018-11-01 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 3,933,489 | 3,324,989 | ||||
| 2018-10-25 | 13G | EIGR / Eiger BioPharmaceuticals, Inc. | 2,415,458 | |||||
| 2018-10-05 | 13D/A | KALA / KALA BIO, Inc. | 2,113,236 | 4,537,478 | ||||
| 2018-08-06 | 13G/A | BCRX / BioCryst Pharmaceuticals, Inc. | 6,984,692 | 9,234,692 | ||||
| 2018-07-10 | 13G/A | 867328601 / Sunesis Pharmaceuticals, Inc. | 35,968,401 | 500,000 | ||||
| 2018-07-02 | 13D | US28249H1041 / Eidos Therapeutics, Inc. | 2,162,671 | |||||
| 2018-04-26 | 13G/A | IFRX / InflaRx N.V. | 1,620,653 | |||||
| 2018-04-02 | 13D | BCRX / BioCryst Pharmaceuticals, Inc. | 6,984,692 | 6,984,692 | ||||
| 2018-03-27 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 4,462,313 | 3,933,489 | ||||
| 2018-02-16 | 13D/A | RARX / Ra Pharmaceuticals, Inc. | 1,351,808 | 3,851,808 | ||||
| 2018-02-14 | 13G | SPRO / Spero Therapeutics, Inc. | 1,225,647 | |||||
| 2018-02-14 | 13G | KDMN / Kadmon Holdings Inc | 8,029,342 | |||||
| 2018-02-14 | 13G | TARA / Protara Therapeutics, Inc. | 0 | 1,679,205 | ||||
| 2018-02-14 | 13G | KRYS / Krystal Biotech, Inc. | 700,000 | |||||
| 2018-02-14 | 13G | BHVN / Biohaven Ltd. | 1,997,278 | |||||
| 2018-02-14 | 13G | BCRX / BioCryst Pharmaceuticals, Inc. | 3,094,064 | 6,984,692 | ||||
| 2018-02-14 | 13G/A | ABIO / ARCA biopharma, Inc. | 5,567,351 | 324,490 | ||||
| 2018-02-14 | 13G/A | AVXS / AveXis, Inc. | 1,890,796 | 1,171,278 | ||||
| 2018-02-14 | 13G/A | NLTX / Neoleukin Therapeutics, Inc. | 2,191,977 | 0 | ||||
| 2018-02-14 | 13G/A | SBBP / Strongbridge Biopharma plc | 2,279,099 | 0 | ||||
| 2018-02-14 | 13G/A | TENX / Tenax Therapeutics, Inc. | 2,389,700 | 0 | ||||
| 2018-02-14 | 13G/A | ZGNX / Zogenix Inc | 2,451,237 | 1,145,268 | ||||
| 2018-02-14 | 13G/A | ASND / Ascendis Pharma A/S | 5,409,990 | 5,580,690 | ||||
| 2018-02-14 | 13D | KALA / KALA BIO, Inc. | 2,113,236 | |||||
| 2018-02-14 | 13G | ECYT / Endocyte, Inc. | 3,364,648 | |||||
| 2018-02-14 | 13G/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 13,633,220 | 585,890 | ||||
| 2018-02-09 | 13D | SLDB / Solid Biosciences Inc. | 2,689,444 | |||||
| 2018-01-19 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 5,074,013 | 4,462,313 | ||||
| 2017-12-20 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 4,588,536 | 5,074,013 | ||||
| 2017-12-15 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 4,588,536 | 4,588,536 | ||||
| 2017-12-11 | 13G | IFRX / InflaRx N.V. | 2,876,080 | |||||
| 2017-12-11 | 13G | SCPH / scPharmaceuticals Inc. | 2,857,143 | |||||
| 2017-11-15 | 13D/A | WVE / Wave Life Sciences Ltd. | 7,088,651 | 7,512,049 | ||||
| 2017-11-13 | 13D/A | KALV / KalVista Pharmaceuticals, Inc. | 591,070 | 1,441,070 | ||||
| 2017-11-13 | 13G | 867328601 / Sunesis Pharmaceuticals, Inc. | 3,596,840 | |||||
| 2017-04-13 | 13D/A | DRNA / Dicerna Pharmaceuticals Inc | 4,588,536 | |||||
| 2017-02-15 | 13G/A | ASND / Ascendis Pharma A/S | 5,378,716 | 5,409,990 | ||||
| 2017-02-15 | 13G/A | SNWV / SANUWAVE Health, Inc. | 0 | |||||
| 2017-02-15 | 13G/A | TGTX / TG Therapeutics, Inc. | 2,813,779 | 1,004,314 | ||||
| 2017-02-15 | 13G/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 11,222,893 | 13,633,220 | ||||
| 2017-02-15 | 13G/A | PTGX / Protagonist Therapeutics, Inc. | 1,109,229 | 692,563 | ||||
| 2017-02-15 | 13G/A | SBBP / Strongbridge Biopharma plc | 2,690,702 | 2,279,099 | ||||
| 2017-02-15 | 13G/A | DSCI / Derma Sciences, Inc. | 2,055,676 | 0 | ||||
| 2017-02-15 | 13G/A | TENX / Tenax Therapeutics, Inc. | 2,389,700 | 2,389,700 | ||||
| 2017-02-15 | 13G/A | ZGNX / Zogenix Inc | 2,253,237 | 2,451,237 | ||||
| 2017-02-15 | 13G/A | NLTX / Neoleukin Therapeutics, Inc. | 1,619,977 | 2,191,977 | ||||
| 2017-02-15 | 13G/A | ZYNE / Zynerba Pharmaceuticals Inc | 507,191 | 0 | ||||
| 2017-02-15 | 13G/A | ARDX / Ardelyx, Inc. | 3,625,943 | 2,103,530 | ||||
| 2017-02-15 | 13G/A | RGLS / Regulus Therapeutics Inc. | 3,482,924 | 0 | ||||
| 2017-02-15 | 13G/A | ACRS / Aclaris Therapeutics, Inc. | 1,530,020 | 0 | ||||
| 2017-02-15 | 13G/A | CDTX / Cidara Therapeutics, Inc. | 1,174,219 | 0 | ||||
| 2017-02-15 | 13G/A | TARA / Protara Therapeutics, Inc. | 1,476,931 | 0 | ||||
| 2017-02-14 | 13D | KALV / KalVista Pharmaceuticals, Inc. | 591,070 | |||||
| 2017-02-14 | 13G/A | ABIO / ARCA biopharma, Inc. | 928,195 | 556,735 | ||||
| 2017-02-14 | 13G/A | AVXS / AveXis, Inc. | 1,890,796 | 1,890,796 | ||||
| 2017-02-14 | 13G/A | SIOX / Sio Gene Therapies Inc. | 5,000,000 | 0 | ||||
| 2016-12-23 | 13G | AVXS / AveXis, Inc. | 1,890,796 | |||||
| 2016-12-06 | 13G/A | ASND / Ascendis Pharma A/S | 2,927,857 | 5,378,716 | ||||
| 2016-11-09 | 13D | RARX / Ra Pharmaceuticals, Inc. | 1,351,808 | |||||
| 2016-10-21 | 13G/A | ARCT / Arcturus Therapeutics Holdings Inc. | 3,032,911 | 1,308,234 | ||||
| 2016-10-06 | 13G/A | ACRS / Aclaris Therapeutics, Inc. | 2,564,553 | 1,530,020 | ||||
| 2016-08-25 | 13G | PTGX / Protagonist Therapeutics, Inc. | 1,109,229 | |||||
| 2016-08-15 | 13G | VTAE / Vitae Pharmaceuticals, Inc. | 2,119,036 | |||||
| 2016-07-28 | 13G | ARDX / Ardelyx, Inc. | 739,669 | 3,625,943 | ||||
| 2016-06-07 | 13G/A | ASND / Ascendis Pharma A/S | 1,671,447 | 2,927,857 | ||||
| 2016-02-16 | 13G/A | BPMC / Blueprint Medicines Corporation | 878,348 | |||||
| 2016-02-16 | 13G/A | TRVN / Trevena, Inc. | 0 | |||||
| 2016-02-16 | 13G/A | ARDX / Ardelyx, Inc. | 1,897,620 | 739,669 | ||||
| 2016-02-16 | 13G/A | ABUS / Arbutus Biopharma Corporation | 0 | |||||
| 2016-02-16 | 13G/A | RGLS / Regulus Therapeutics Inc. | 3,482,924 | |||||
| 2016-02-16 | 13G/A | ACRS / Aclaris Therapeutics, Inc. | 2,237,130 | 2,564,553 | ||||
| 2016-02-16 | 13G/A | AUPH / Aurinia Pharmaceuticals Inc. | 3,092,595 | 618,519 | ||||
| 2016-02-16 | 13G/A | CDTX / Cidara Therapeutics, Inc. | 1,488,248 | 1,174,219 | ||||
| 2016-02-16 | 13G/A | ASND / Ascendis Pharma A/S | 1,428,776 | 1,671,447 | ||||
| 2016-02-16 | 13G/A | ZYNE / Zynerba Pharmaceuticals Inc | 578,575 | 507,191 | ||||
| 2016-02-16 | 13G | SIOX / Sio Gene Therapies Inc. | 5,000,000 | |||||
| 2016-02-16 | 13G/A | TENX / Tenax Therapeutics, Inc. | 2,389,700 | |||||
| 2016-02-16 | 13G/A | BBI / Brickell Biotech Inc | 0 | |||||
| 2016-02-16 | 13G/A | BCRX / BioCryst Pharmaceuticals, Inc. | 3,094,064 | |||||
| 2016-02-16 | 13G/A | ABIO / ARCA biopharma, Inc. | 5,678,592 | 928,195 | ||||
| 2016-02-16 | 13G/A | ARMP / Armata Pharmaceuticals, Inc. | 365,393 | |||||
| 2016-02-16 | 13G/A | NLTX / Neoleukin Therapeutics, Inc. | 1,032,151 | 1,619,977 | ||||
| 2016-02-16 | 13G/A | ZGNX / Zogenix Inc | 1,840,716 | 2,253,237 | ||||
| 2016-02-16 | 13G/A | WGBS / WaferGen Bio-Systems, Inc. | 0 | 560,000 | ||||
| 2016-02-16 | 13G/A | TARA / Protara Therapeutics, Inc. | 1,476,931 | |||||
| 2016-02-16 | 13G/A | XNCR / Xencor, Inc. | 3,156,844 | 0 | ||||
| 2016-02-16 | 13G/A | COLL / Collegium Pharmaceutical, Inc. | 1,545,410 | 857,683 | ||||
| 2016-02-16 | 13G/A | AGRX / Agile Therapeutics, Inc. | 0 | |||||
| 2016-02-16 | 13G/A | SCYX / SCYNEXIS, Inc. | 0 | |||||
| 2016-02-16 | 13G/A | ACAD / ACADIA Pharmaceuticals Inc. | 2,496,178 | 0 | ||||
| 2016-02-16 | 13G/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 11,222,893 | |||||
| 2016-02-16 | 13G/A | DVAX / Dynavax Technologies Corporation | 0 | |||||
| 2016-02-16 | 13G/A | TGTX / TG Therapeutics, Inc. | 2,813,779 | |||||
| 2016-01-29 | 13G | DSCI / Derma Sciences, Inc. | 2,055,676 | |||||
| 2015-11-27 | 13D | WVE / Wave Life Sciences Ltd. | 7,088,651 | |||||
| 2015-11-18 | 13G/A | ARCT / Arcturus Therapeutics Holdings Inc. | 1,660,594 | 3,032,911 | ||||
| 2015-10-26 | 13G | SBBP / Strongbridge Biopharma plc | 2,690,702 | |||||
| 2015-10-14 | 13G | ZYNE / Zynerba Pharmaceuticals Inc | 578,575 | |||||
| 2015-10-13 | 13G | ACRS / Aclaris Therapeutics, Inc. | 2,237,130 | |||||
| 2015-10-08 | 13G | ZGNX / Zogenix Inc | 1,840,716 | |||||
| 2015-09-29 | 13G/A | SGMO / Sangamo Therapeutics, Inc. | 1,220,209 | |||||
| 2015-08-24 | 13G | NLTX / Neoleukin Therapeutics, Inc. | 1,032,151 | |||||
| 2015-07-07 | 13G | ARCT / Arcturus Therapeutics Holdings Inc. | 1,660,594 | |||||
| 2015-06-25 | 13G | ABIO / ARCA biopharma, Inc. | 5,678,592 | |||||
| 2015-06-05 | 13G | ARDX / Ardelyx, Inc. | 1,897,620 | |||||
| 2015-05-15 | 13G | COLL / Collegium Pharmaceutical, Inc. | 1,545,410 | |||||
| 2015-05-14 | 13G | XNCR / Xencor, Inc. | 3,156,844 | |||||
| 2015-05-08 | 13G | BPMC / Blueprint Medicines Corporation | 1,488,248 | |||||
| 2015-05-08 | 13G | CDTX / Cidara Therapeutics, Inc. | 967,858 | 1,488,248 | ||||
| 2015-05-08 | 13G | ASND / Ascendis Pharma A/S | 1,428,776 | |||||
| 2015-04-21 | 13G | CDTX / Cidara Therapeutics, Inc. | 967,858 | |||||
| 2015-04-03 | 13G/A | ACAD / ACADIA Pharmaceuticals Inc. | 2,496,178 | |||||
| 2015-03-25 | 13G | AUPH / Aurinia Pharmaceuticals Inc. | 3,092,595 | |||||
| 2015-02-19 | 13G/A | SGMO / Sangamo Therapeutics, Inc. | 2,731,389 | |||||
| 2015-02-17 | 13G/A | OCRX / Ocera Therapeutics, Inc. | 523,035 | |||||
| 2015-02-17 | 13G/A | PSDV / pSivida Corp. | 0 | |||||
| 2015-02-17 | 13G/A | TRVN / Trevena, Inc. | 2,974,647 | |||||
| 2015-02-17 | 13G/A | SNWV / SANUWAVE Health, Inc. | 5,019,945 | |||||
| 2015-02-17 | 13G/A | TENX / Tenax Therapeutics, Inc. | 2,670,300 | |||||
| 2015-02-17 | 13G/A | ARAV / Aravive, Inc. | 231,267 | |||||
| 2015-02-17 | 13G/A | SCYX / SCYNEXIS, Inc. | 840,000 | |||||
| 2015-02-17 | 13G/A | WGBS / WaferGen Bio-Systems, Inc. | 560,000 | |||||
| 2015-02-17 | 13G/A | ENTA / Enanta Pharmaceuticals, Inc. | 0 | |||||
| 2015-02-17 | 13G/A | 76028H209 / Repros Therapeutics, Inc. | 0 | |||||
| 2015-02-17 | 13G/A | APHB / Ampliphi Biosciences Corp. | 26,785,712 | |||||
| 2015-02-17 | 13G/A | ENZ / Enzo Biochem, Inc. | 0 | |||||
| 2015-02-17 | 13G/A | ARWR / Arrowhead Pharmaceuticals, Inc. | 0 | |||||
| 2015-02-17 | 13G/A | MRTX / Mirati Therapeutics, Inc. | 165,516 | |||||
| 2015-02-17 | 13G/A | PRTA / Prothena Corporation plc | 0 | |||||
| 2015-02-17 | 13G/A | DVAX / Dynavax Technologies Corporation | 2,603,044 | |||||
| 2015-02-17 | 13G/A | TNGNQ / Tengion, Inc. | 3,984,267 | |||||
| 2015-02-17 | 13G/A | RGLS / Regulus Therapeutics Inc. | 4,742,911 | |||||
| 2015-02-17 | 13G/A | BBI / Brickell Biotech Inc | 6,203,690 | |||||
| 2015-02-17 | 13G/A | FURX / Furiex Pharmaceuticals, Inc. | 0 | |||||
| 2015-02-17 | 13G/A | TGTX / TG Therapeutics, Inc. | 3,350,449 | |||||
| 2015-02-17 | 13G/A | VIRX / Viracta Therapeutics, Inc. | 0 | |||||
| 2015-02-17 | 13G/A | TARA / Protara Therapeutics, Inc. | 1,250,000 | |||||
| 2015-02-17 | 13G/A | NVAX / Novavax, Inc. | 3,241,083 | |||||
| 2015-02-17 | 13G/A | TXMD / TherapeuticsMD, Inc. | 3,211,132 | |||||
| 2015-02-17 | 13G/A | BCRX / BioCryst Pharmaceuticals, Inc. | 7,050,356 | |||||
| 2015-02-17 | 13G/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 9,200,000 | |||||
| 2015-02-17 | 13G/A | ACAD / ACADIA Pharmaceuticals Inc. | 1,027,300 | |||||
| 2015-02-17 | 13G/A | SGMO / Sangamo Therapeutics, Inc. | 7,220,209 | |||||
| 2015-02-17 | 13G/A | DSCI / Derma Sciences, Inc. | 363,636 | |||||
| 2015-02-17 | 13G/A | DYAX / Dyax Corp. | 4,945,697 | |||||
| 2015-01-30 | 13G | AGRX / Agile Therapeutics, Inc. | 1,458,792 | |||||
| 2015-01-20 | 13G | ABUS / Arbutus Biopharma Corporation | 2,214,800 | |||||
| 2015-01-20 | 13D/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 19,957,061 | |||||
| 2015-01-20 | 13G/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 7,091,103 | |||||
| 2014-12-12 | 13G | TRVN / Trevena, Inc. | 2,974,647 | |||||
| 2014-11-07 | 13G | RGLS / Regulus Therapeutics Inc. | 4,742,911 | |||||
| 2014-10-31 | 13G | TARA / Protara Therapeutics, Inc. | 1,250,000 | |||||
| 2014-10-17 | 13G | TGTX / TG Therapeutics, Inc. | 3,145,571 | |||||
| 2014-09-26 | 13G | TENX / Tenax Therapeutics, Inc. | 2,264,528 | |||||
| 2014-09-26 | 13G/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 11,032,014 | |||||
| 2014-09-02 | 13G | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 17,704,362 | |||||
| 2014-08-29 | 13G | WGBS / WaferGen Bio-Systems, Inc. | 560,000 | |||||
| 2014-08-27 | 13D/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 18,539,655 | |||||
| 2014-08-20 | 13D/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 21,251,007 | |||||
| 2014-08-19 | 13G | BBI / Brickell Biotech Inc | 5,475,419 | |||||
| 2014-06-24 | 13D/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 22,486,007 | |||||
| 2014-05-08 | 13G | SCYX / SCYNEXIS, Inc. | 840,000 | |||||
| 2014-05-02 | 13G | DYAX / Dyax Corp. | 9,015,230 | |||||
| 2014-04-09 | 13G | ARAV / Aravive, Inc. | 1,404,688 | |||||
| 2014-04-01 | 13G | ENTA / Enanta Pharmaceuticals, Inc. | 1,541,078 | |||||
| 2014-03-24 | 13G | PSDV / pSivida Corp. | 2,555,659 | |||||
| 2014-03-24 | 13G | SNWV / SANUWAVE Health, Inc. | 4,674,972 | |||||
| 2014-03-21 | 13D/A | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 23,366,007 | |||||
| 2014-03-21 | 13G/A | DSCI / Derma Sciences, Inc. | 1,953,071 | |||||
| 2014-03-21 | 13G | APHB / Ampliphi Biosciences Corp. | 26,785,712 | |||||
| 2014-03-18 | 13G | 76028H209 / Repros Therapeutics, Inc. | 1,439,048 | |||||
| 2014-02-14 | 13G/A | KERX / Keryx Biopharmaceuticals, Inc. | 0 | |||||
| 2014-02-14 | 13G/A | SSKN / STRATA Skin Sciences, Inc. | 0 | |||||
| 2014-02-14 | 13G/A | LUMO / Lumos Pharma, Inc. | 0 | |||||
| 2014-02-14 | 13G/A | OMER / Omeros Corporation | 0 | |||||
| 2014-02-14 | 13G/A | TNGNQ / Tengion, Inc. | 948,856 | |||||
| 2014-02-14 | 13G/A | INSM / Insmed Incorporated | 0 | |||||
| 2014-02-14 | 13G/A | MEIP / MEI Pharma, Inc. | 816,666 | |||||
| 2014-02-14 | 13G/A | NVAX / Novavax, Inc. | 10,811,888 | |||||
| 2014-02-14 | 13G/A | SNMX / Senomyx, Inc. | 0 | |||||
| 2014-02-14 | 13G/A | VIRX / Viracta Therapeutics, Inc. | 4,869,261 | |||||
| 2014-02-14 | 13G/A | ACAD / ACADIA Pharmaceuticals Inc. | 1,169,898 | |||||
| 2014-02-14 | 13G/A | SGMO / Sangamo Therapeutics, Inc. | 5,227,272 | |||||
| 2014-02-14 | 13G/A | OCRX / Ocera Therapeutics, Inc. | 767,255 | |||||
| 2014-02-14 | 13G/A | CCXI / Churchill Capital Corp XI | 0 | |||||
| 2014-02-14 | 13G/A | DVAX / Dynavax Technologies Corporation | 25,999,886 | |||||
| 2014-02-14 | 13G/A | HPTX / Hyperion Therapeutics Inc | 0 | |||||
| 2014-02-14 | 13G/A | FBIO / Fortress Biotech, Inc. | 0 | |||||
| 2014-02-14 | 13G/A | PRTA / Prothena Corporation plc | 1,641,167 | |||||
| 2014-02-14 | 13G | MRTX / Mirati Therapeutics, Inc. | 822,284 | |||||
| 2014-02-14 | 13G | TXMD / TherapeuticsMD, Inc. | 11,660,108 | |||||
| 2014-02-14 | 13G/A | ENZ / Enzo Biochem, Inc. | 2,268,653 | |||||
| 2014-02-14 | 13G/A | XOMA / XOMA Royalty Corporation | 687,879 | |||||
| 2014-02-14 | 13G/A | ARWR / Arrowhead Pharmaceuticals, Inc. | 3,929,016 | |||||
| 2014-02-14 | 13G/A | BCRX / BioCryst Pharmaceuticals, Inc. | 4,347,456 | |||||
| 2014-02-14 | 13G/A | DSCI / Derma Sciences, Inc. | 1,589,435 | |||||
| 2014-02-14 | 13G/A | DYAX / Dyax Corp. | 5,761,497 | |||||
| 2014-02-14 | 13G/A | ACHV / Achieve Life Sciences, Inc. | 0 | |||||
| 2014-02-05 | 13D | DRNA / Dicerna Pharmaceuticals Inc | 2,428,571 | |||||
| 2014-02-05 | 13G | FURX / Furiex Pharmaceuticals, Inc. | 750,000 | |||||
| 2013-12-10 | 13G | XNCR / Xencor, Inc. | 2,725,000 | |||||
| 2013-11-14 | 13G/A | ARWR / Arrowhead Pharmaceuticals, Inc. | 3,653,992 | |||||
| 2013-11-05 | 13G | DVAX / Dynavax Technologies Corporation | 25,993,234 | |||||
| 2013-11-01 | 13D | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 20,461,007 | |||||
| 2013-10-04 | 13G | US00448Q2012 / Achillion Pharmaceuticals, Inc. | 14,457,061 | |||||
| 2013-09-13 | 13G | CCXI / Churchill Capital Corp XI | 3,045,380 | |||||
| 2013-08-27 | 13G | PRTA / Prothena Corporation plc | 1,648,599 | |||||
| 2013-08-09 | 13G | ENZ / Enzo Biochem, Inc. | 3,348,029 | |||||
| 2013-08-09 | 13G | BCRX / BioCryst Pharmaceuticals, Inc. | 5,850,000 | |||||
| 2013-07-12 | 13G | TNGNQ / Tengion, Inc. | 414,198 | |||||
| 2013-05-20 | 13G | OMER / Omeros Corporation | 2,953,004 | |||||
| 2013-05-09 | 13G | ARWR / Arrowhead Pharmaceuticals, Inc. | 3,127,401 | |||||
| 2013-05-08 | 13G | OCRX / Ocera Therapeutics, Inc. | 2,700,000 | |||||
| 2013-05-01 | 13G/A | DSCI / Derma Sciences, Inc. | 1,994,876 | |||||
| 2013-03-04 | 13G | HPTX / Hyperion Therapeutics Inc | 866,088 | |||||
| 2013-02-15 | 13G | SSKN / STRATA Skin Sciences, Inc. | 2,992,608 | |||||
| 2013-02-15 | 13G | KERX / Keryx Biopharmaceuticals, Inc. | 5,285,000 | |||||
| 2013-02-15 | 13G | LUMO / Lumos Pharma, Inc. | 1,576,981 | |||||
| 2013-02-14 | 13G/A | ACAD / ACADIA Pharmaceuticals Inc. | 7,347,878 | |||||
| 2013-02-14 | 13G/A | ANTH / Anthera Pharmaceuticals, Inc. | 0 | |||||
| 2013-02-14 | 13G/A | ECYT / Endocyte, Inc. | 0 | |||||
| 2013-02-14 | 13G/A | MEIP / MEI Pharma, Inc. | 991,666 | |||||
| 2013-02-14 | 13G/A | INSM / Insmed Incorporated | 2,433,319 | |||||
| 2013-02-14 | 13G/A | NVAX / Novavax, Inc. | 14,411,748 | |||||
| 2013-02-14 | 13G/A | POZN / Pozen, Inc. | 0 | |||||
| 2013-02-14 | 13G/A | SNMX / Senomyx, Inc. | 3,965,635 | |||||
| 2013-02-14 | 13G/A | SGMO / Sangamo Therapeutics, Inc. | 3,835,776 | |||||
| 2013-02-14 | 13G/A | VIRX / Viracta Therapeutics, Inc. | 4,887,230 | |||||
| 2013-02-14 | 13G/A | VNDA / Vanda Pharmaceuticals Inc. | 0 | |||||
| 2013-02-14 | 13G/A | 032420101 / Anacor Pharmaceuticals, Inc. | 0 | |||||
| 2013-02-14 | 13G/A | ASMB / Assembly Biosciences, Inc. | 628,092 | |||||
| 2013-02-14 | 13G/A | FBIO / Fortress Biotech, Inc. | 1,735,597 | |||||
| 2013-02-14 | 13G/A | XOMA / XOMA Royalty Corporation | 6,698,558 | |||||
| 2013-02-14 | 13G/A | 662,117,262 | ||||||
| 2013-02-14 | 13G/A | BCRX / BioCryst Pharmaceuticals, Inc. | 0 | |||||
| 2013-02-14 | 13G/A | UPI / Uroplasty Inc | 0 | |||||
| 2013-02-14 | 13G/A | DSCI / Derma Sciences, Inc. | 1,599,332 | |||||
| 2013-02-14 | 13G/A | DYAX / Dyax Corp. | 8,528,440 | |||||
| 2013-02-14 | 13G/A | ACHV / Achieve Life Sciences, Inc. | 894,232 | |||||
| 2013-01-03 | 13G | MEIP / MEI Pharma, Inc. | 991,666 | |||||
| 2012-11-13 | 13G | SGMO / Sangamo Therapeutics, Inc. | 2,918,163 | |||||
| 2012-10-03 | 13G | INSM / Insmed Incorporated | 2,459,039 | |||||
| 2012-09-26 | 13G | VIRX / Viracta Therapeutics, Inc. | 2,538,846 | |||||
| 2012-08-30 | 13G | SNMX / Senomyx, Inc. | 2,757,076 | |||||
| 2012-07-27 | 13G | ANTH / Anthera Pharmaceuticals, Inc. | 4,500,000 | |||||
| 2012-07-03 | 13G | 032420101 / Anacor Pharmaceuticals, Inc. | 2,405,177 | |||||
| 2012-07-03 | 13G | ASMB / Assembly Biosciences, Inc. | 1,245,000 | |||||
| 2012-07-03 | 13G | FBIO / Fortress Biotech, Inc. | 1,775,154 | |||||
| 2012-05-22 | 13G | NVAX / Novavax, Inc. | 13,200,000 | |||||
| 2012-03-20 | 13G | UPI / Uroplasty Inc | 1,235,100 | |||||
| 2012-03-16 | 13G | XOMA / XOMA Royalty Corporation | 5,698,809 | |||||
| 2012-03-16 | 13G | BCRX / BioCryst Pharmaceuticals, Inc. | 3,008,433 | |||||
| 2012-02-17 | 13G/A | GEVA / Synageva Biopharma Corp | 181,499 | |||||
| 2012-02-14 | 13G/A | 878193101 / TearLab Corp | 1,020,545 | |||||
| 2012-02-14 | 13G/A | ECYT / Endocyte, Inc. | 2,530,679 | |||||
| 2012-02-14 | 13G/A | SQNM / Sequenom, Inc. | 4,681,026 | |||||
| 2012-02-14 | 13G/A | POZN / Pozen, Inc. | 2,946,944 | |||||
| 2012-02-14 | 13G/A | SVRA / Savara Inc. | 0 | |||||
| 2012-02-14 | 13G/A | TNGNQ / Tengion, Inc. | 1,060,070 | |||||
| 2012-02-14 | 13G/A | US0906721065 / BioTelemetry, Inc. | 0 | |||||
| 2012-02-14 | 13G/A | ALXA / Alexza Pharmaceuticals, Inc. | 1,622,967 | |||||
| 2012-02-14 | 13G/A | ACAD / ACADIA Pharmaceuticals Inc. | 5,269,999 | |||||
| 2012-02-14 | 13G/A | VNDA / Vanda Pharmaceuticals Inc. | 2,444,732 | |||||
| 2012-02-14 | 13G/A | ASMB / Assembly Biosciences, Inc. | 718,519 | |||||
| 2012-02-14 | 13G/A | GNTA / Genenta Science S.p.A. - Depositary Receipt (Common Stock) | 210,536,030 | |||||
| 2012-02-14 | 13G/A | DSCI / Derma Sciences, Inc. | 1,055,648 | |||||
| 2012-02-14 | 13G/A | DYAX / Dyax Corp. | 7,072,436 | |||||
| 2012-02-14 | 13G/A | GEVA / Synageva Biopharma Corp | 0 | |||||
| 2012-02-14 | 13G/A | ACHV / Achieve Life Sciences, Inc. | 659,051 |
