| 내부자 지분 | 41,783,886 shares |
내부자 센티멘트 점수
내부자 센티멘트 점수를 통해서 내부자들이 법인 지분을 매입하는 기업들에 대해서 알아볼 수 있습니다.
이는 내부자의 누적도가 가장 높은 기업을 식별하는 정교하고 복합적인 지수를 분석하는 계량 모델의 결과 값입니다. 스코어링 모델은 이전 90일 동안 매수한 "내부자의 순 숫자", "매수한 주식의 총합", "내부자가 소유한 주식의 총합"의 조합을 사용합니다. 점수는 0에서 100 사이이며, 점수가 높을수록 피어(Peer: 동종업계 경쟁기업)에 대한 누적도가 높다는 것을 나타내며, 평균은 50입니다.
업데이트 주기: 일별
내부자의 누적도가 가장 높은 기업 목록을 확인할 수 있는 내부자들의 최다 선택(Insiders Top Picks)을 참고하십시오.
내부 경영진 센티멘트 점수
내부 경영진 센티멘트 점수를 통해서 내부 경영진들이 법인 지분을 매입하는 기업들에 대해서 알아볼 수 있습니다.
내부 거래의 정의에 따라 내부 경영진(기업 임원)도 내부자이지만, 다른 내부자(10% 주주 및 이사회 구성원)들과는 달리 내부 경영진은 매일 회사에서 근무하며, 거래 시에 자신의 자금을 사용합니다. (많은 경우에 10% 주주 및 이사회 구성원은 다른 사람의 자금을 관리하는 자금 관리자입니다.) 따라서 내부 경영진(기업 임원: Officer)의 내부 거래는 훨씬 더 중요하며 올바른 분석이 필요합니다.
내부자 센티멘트 점수와 마찬가지로 임원 감정 점수는 가장 높은 수준의 임원 축적을 가진 기업을 식별하는 정교하고 복합적인 지수 퀀트(Multi-factor quantitative) 모델의 결과입니다.
업데이트 주기: 일별
내부자의 누적도가 가장 높은 기업 목록을 확인할 수 있는 내부자들의 최다 선택(Insiders Top Picks)을 참고하십시오.
주요 내부자 지표
이 수치는 해당 기업이 다양한 내부자 지표에 따라 어떻게 순위를 매겨지는 지를 설명합니다. 백분위 순위는 이 기업이 미국 시장의 다른 기업들과 어떻게 비교되는지 보여줍니다. 순위가 높을수록 더 나은 상황에 있다는 것을 의미합니다.
예를 들어, 일반적으로 내부자의 매입은 긍정적인 지표라고 간주되어지기 때문에, 내부자의 매입(내부자의 매각, 역시도)가 적은 기업보다 내부자의 매입이 많은 기업은 순위가 높을 것입니다.
내부자의 순 매입(순위)
N/A
내부자의 순 매입(Net Number of Insiders Buying)는 내부자 매수의 총 수에서 지난 90일 동안의 내부자 매도의 총 수를 뺀 값입니다. 여기에 백분위 순위가 표시됩니다(범위: 0~100%).
내부자가 매입한 플로트 비율 (순위)
N/A
"내부자가 매입한 플로트 비율(Percent of Float Bought by Insiders)"은 내부자가 매입한 주식의 총 수에서 내부자가 매도한 주식의 총 수를 뺀 값을 전체 플로트로 나눈 값에 100을 곱한 값입니다. * ((내부자가 매입한 주식의 총 수 - 내부자가 매도한 주식의 총 수) ÷ 전체 플로트) x 100
내부자 트레이딩 차트
Aravive, Inc. 내부자의 매매 거래는 아래 차트에 나와 있습니다. 내부자들은 기업의 임원(내부 경영진), 이사 또는 주요 투자자입니다. 일반적으로 내부자가 중요한 비공개 정보를 기반으로 자신이 속한 기업을 거래하는 것은 불법으로 간주됩니다. 이것은 내부자가 자신의 기업 내에서 행하는 모든 거래가 불법이라는 것을 뜻은 아닙니다. 그러나 그들은 자신들의 모든 거래를 양식 4를 통해 SEC에 보고해야만 합니다.
내부자의 명단 및 이익 지표
아래 표는 공개된 내부자의 목록이며, SEC에 공개된 제출 문서에서 자동으로 생성됩니다. "이름", "가장 최근의 직급", "이사, 임원 또는 10% 주주"에 대한 지정 외에도 최근에 공개된 보유 주식에 대한 정보를 보여줍니다. 또한 가능한 경우 내부자의 과거 거래 실적도 확인 가능합니다. 과거 거래 실적은 내부자가 실제 "공개 시장"(Open market) 매입 거래를 수행한 실적을 가중 평균한 값입니다. 이 계산 방법에 대한 자세한 내용은 유튜브 웨비나 를 참조하시면 됩니다.
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| 내부자 | 평균 이익률 (%) | 소유 지분 |
주식 분할 |
|---|
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내부자의 매입 내역 추적: 단기 이익 분석
이 섹션에서는 ARAV / Aravive, Inc.에서 계획되지 않은 "공개 시장"(Open market)의 내부자가 매입한 모든 상품의 수익성을 분석합니다. 이 분석을 통해서 내부자가 비정상적인 수익을 지속적으로 창출하는지 파악하는 데 도움이 되며, 이러한 분석은 수행해볼 가치가 있습니다. 이 분석은 개별 거래 후 1년 동안 수행한 것이며, 결과는 이론 값입니다. .
아래 표는 사전 거래 계획(Automated trading plan)에 포함되지 않은 가장 최근의 "공개 시장"(Open market)에서의 매입을 보여줍니다.
조정된 가격은 분할 조정 가격입니다. 조정된 지분은 분할 조정 지분입니다.
내부자 매매의 실적: 단기 손실 분석
이 섹선에서는 ARAV / Aravive, Inc.에서 이루어진 "공개 시장(Open market)"에서의 모든 계획되지 않은 내부자 매매의 단기 손실 회피(Short-term loss avoidance)를 분석합니다. 일관된 손실 회피 패턴을 통해서 향후 매매 거래가 가격 하락을 초래할 수도 있음을 예상할 수 있습니다. 이 분석은 각 각 매매 거래 후 1년 동안의 자료이며, 결과는 이론 값입니다. .
아래 표는 사전 거래 계획(Automated trading plan)에 포함되지 않은 가장 최근의 공개 시장에서의 매매를 보여줍니다.
조정된 가격은 분할 조정 가격입니다. 조정된 지분은 분할 조정 지분입니다.
거래 내역
전체 거래 내역을 보려면 링크 아이콘을 클릭하세요. 10b5-1 자동 거래 계획의 일부로 보고된 거래는 10b-5 열에 X 표시가 나타납니다.
| 보고일 | 거래일 | 양식 | 내부자 | 티커 | 증권 소유권 | 코드 | 직접 | 행사 가격 |
단위 가격 |
단위 변동 |
가치 변동 (단위: 1,000) |
잔여 옵션 |
잔여 주식 |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-10-27 | 2022-10-24 | 4/A | Ho Peter Tai-Ching | ARAV | Common stock | I | 0.9199 | 54,353 | 50 | 55,353 | ||||
| 2022-10-27 | 2022-10-24 | 4/A | Zhang Eric | ARAV | Common stock | I | 0.9199 | 543,537 | 500 | 1,403,303 | ||||
| 2022-10-26 | 2022-10-24 | 4 | Giaccia Amato | ARAV | Common stock | D | 0.9199 | 271,768 | 250 | 1,213,648 | ||||
| 2022-10-26 | 2022-10-24 | 4 | Zhang Eric | ARAV | Common stock | D | 0.9199 | 543,537 | 500 | 1,403,303 | ||||
| 2022-10-26 | 2022-10-24 | 4 | HOWARD RUDY | ARAV | Common stock | D | 0.9199 | 10,870 | 10 | 10,870 | ||||
| 2022-10-26 | 2022-10-24 | 4 | ESHELMAN FREDRIC N | ARAV | Common Stock | I | 0.9199 | 16,306,120 | 15,000 | 25,517,889 | ||||
| 2022-10-26 | 2022-10-24 | 4 | Ho Peter Tai-Ching | ARAV | Common stock | D | 0.9199 | 54,353 | 50 | 55,353 | ||||
| 2022-10-26 | 2022-10-24 | 4 | McIntyre Gail Frances | ARAV | Common stock | D | 0.9199 | 54,353 | 50 | 65,490 | ||||
| 2022-04-04 | 2022-04-01 | 4 | ESHELMAN FREDRIC N | ARAV | Pre-Funded Warrant (right to buy) | I | 0.00 | 4,545,455 | 0 | |||||
| 2022-04-04 | 2022-04-01 | 4 | ESHELMAN FREDRIC N | ARAV | Common Stock | I | 0.0001 | 4,545,455 | 0 | 9,211,769 | ||||
| 2022-03-31 | 2022-03-29 | 4 | ESHELMAN FREDRIC N | ARAV | Warrant (right to buy) | I | 2.20 | 2.2000 | 860,216 | 1,892 | 860,216 | |||
| 2022-03-31 | 2022-03-29 | 4 | ESHELMAN FREDRIC N See Footnote 1 | ARAV | Common Stock | I | 2.3250 | 860,216 | 2,000 | 4,666,314 | ||||
| 2022-03-22 | 2022-03-21 | 4 | Dove Leonard Scott | ARAV | Stock Option (Right to buy) | D | 1.89 | 200,000 | 200,000 | |||||
| 2022-01-25 | 2022-01-24 | 4 | Rangwala Reshma | ARAV | Stock Option (Right to buy) | D | 2.18 | 175,000 | 175,000 | |||||
| 2022-01-25 | 2022-01-24 | 4 | Shah Vinay | ARAV | Stock Option (Right to buy) | D | 2.18 | 175,000 | 175,000 | |||||
| 2022-01-25 | 2022-01-24 | 4 | McIntyre Gail Frances | ARAV | Stock Option (Right to buy) | D | 2.18 | 425,000 | 425,000 | |||||
| 2022-01-05 | 2022-01-03 | 4 | ESHELMAN FREDRIC N | ARAV | Pre-Funded Warrant (right to buy) | I | 0.00 | 2.2000 | 4,545,455 | 10,000 | 4,545,455 | |||
| 2021-12-23 | 2021-12-03 | 4 | Giaccia Amato | ARAV | Common Stock | D | -48,366 | 941,880 | ||||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Stock Option | D | 0.24 | -500 | 8,620 | |||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Stock Option | D | 0.24 | -38,761 | 0 | |||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Stock Option | D | 0.06 | -12,350 | 0 | |||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 3.2200 | -39 | -0 | 990,246 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 3.2200 | -2,954 | -10 | 990,285 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 3.2200 | -252 | -1 | 993,239 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0.2400 | 500 | 0 | 993,491 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0.2400 | 38,761 | 9 | 992,991 | ||||
| 2021-12-02 | 2021-11-30 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0.0600 | 12,350 | 1 | 954,230 | ||||
| 2021-09-13 | 2021-09-10 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 3.97 | 22,812 | 22,812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Giaccia Amato | ARAV | Stock Option | D | 3.97 | 22,812 | 22,812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Ho Peter Tai-Ching | ARAV | Stock Option | D | 3.97 | 22,812 | 22,812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | ROGERS MICHAEL W | ARAV | Stock Option | D | 3.97 | 22,812 | 22,812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Hohneker John | ARAV | Stock Option | D | 3.97 | 22,812 | 22,812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Zhang Eric | ARAV | Stock Option | D | 3.97 | 22,812 | 22,812 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Kirk Sigurd | ARAV | Stock Option | D | 3.97 | 22,812 | 22,812 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Kirk Sigurd | ARAV | Stock Options | D | 5.80 | 5,245 | 5,245 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Kirk Sigurd | ARAV | Stock Options | D | 5.80 | 15,435 | 15,435 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Ho Peter Tai-Ching | ARAV | Stock Options | D | 5.80 | 5,245 | 5,245 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Ho Peter Tai-Ching | ARAV | Stock Options | D | 5.80 | 15,435 | 15,435 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Hohneker John | ARAV | Stock Options | D | 5.80 | 5,245 | 5,245 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Hohneker John | ARAV | Stock Options | D | 5.80 | 15,435 | 15,435 | |||||
| 2021-06-29 | 2021-06-29 | 4 | McIntyre Gail Frances | ARAV | Common Stock | D | 5.3450 | 1,000 | 5 | 11,137 | ||||
| 2021-06-29 | 2021-06-29 | 4 | Shah Vinay | ARAV | Common Stock | D | 5.3100 | 1,000 | 5 | 190,842 | ||||
| 2021-05-21 | 3 | Ho Peter Tai-Ching Hui Ping Ho Trust, 2016 | ARAV | Common Stock | I | 1,000 | ||||||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Stock Option (Right to buy) | D | 0.06 | -4,028 | 0 | |||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Stock Option (Right to buy) | D | 0.06 | -8,055 | 0 | |||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Common Stock | D | -12,083 | 941,880 | ||||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0.0600 | 4,028 | 0 | 953,963 | ||||
| 2021-03-22 | 2021-03-19 | 4 | Giaccia Amato | ARAV | Common Stock | D | 0.0600 | 8,055 | 0 | 949,935 | ||||
| 2021-02-17 | 2021-02-12 | 4 | ESHELMAN FREDRIC N | ARAV | Common stock | I | 7.2900 | 2,875,000 | 20,959 | 3,806,098 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Rangwala Reshma | ARAV | Stock Options | D | 5.95 | 10,000 | 10,000 | |||||
| 2021-01-26 | 2021-01-25 | 4 | McIntyre Gail Frances | ARAV | Stock Options | D | 5.95 | 165,000 | 165,000 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Shah Vinay | ARAV | Stock Options | D | 5.95 | 60,000 | 60,000 | |||||
| 2020-12-07 | 2020-12-04 | 4 | Shah Vinay | ARAV | Common Stock | D | 5.7600 | 8,000 | 46 | 189,842 | ||||
| 2020-12-07 | 2020-12-04 | 4 | McIntyre Gail Frances | ARAV | Common Stock | D | 5.7700 | 8,000 | 46 | 10,137 | ||||
| 2020-09-29 | 2020-09-28 | 4 | Rangwala Reshma | ARAV | Stock Option | D | 4.95 | 75,000 | 75,000 | |||||
| 2020-09-17 | 2020-09-15 | 4 | ROGERS MICHAEL W | ARAV | Stock Option | D | 5.99 | 14,987 | 14,987 | |||||
| 2020-09-17 | 2020-09-15 | 4 | ROGERS MICHAEL W | ARAV | Stock Option | D | 5.99 | 15,024 | 15,024 | |||||
| 2020-09-15 | 2020-09-14 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 5.63 | 16,029 | 16,029 | |||||
| 2020-09-15 | 2020-09-14 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 5.63 | 16,029 | 16,029 | |||||
| 2020-09-15 | 2020-09-14 | 4 | Zhang Eric | ARAV | Stock Option | D | 5.63 | 16,029 | 16,029 | |||||
| 2020-09-15 | 2020-09-14 | 4 | Giaccia Amato | ARAV | Stock Option | D | 5.63 | 16,029 | 16,029 | |||||
| 2020-06-03 | 2020-06-01 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 12.72 | 3,226 | 3,226 | |||||
| 2020-06-03 | 2020-06-01 | 4 | ESHELMAN FREDRIC N | ARAV | Stock Option | D | 12.72 | 7,500 | 7,500 | |||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1,862,196 | ||||||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1,862,196 | ||||||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1,862,196 | ||||||||
| 2020-04-10 | 3 | Eshelman Ventures, LLC | ARAV | Common Stock | I | 1,862,196 | ||||||||
| 2020-04-09 | 2020-04-08 | 4 | McIntyre Gail Frances | ARAV | Stock Option | D | 6.16 | 80,000 | 80,000 | |||||
| 2020-04-09 | 2020-04-08 | 4 | Hemrajani Rekha | ARAV | Common Stock | D | -42,750 | 14,250 | ||||||
| 2020-04-09 | 2020-04-08 | 4 | Shepard Jay | ARAV | Common Stock | D | -9,291 | 61,201 | ||||||
| 2020-01-24 | 2020-01-22 | 4 | McIntyre Gail Frances | ARAV | Stock Option | D | 10.84 | 48,583 | 48,583 | |||||
| 2020-01-24 | 2020-01-22 | 4 | Shah Vinay | ARAV | Stock Option | D | 10.84 | 34,826 | 34,826 | |||||
| 2020-01-09 | 2020-01-09 | 4 | Shepard Jay | ARAV | Stock Option | D | 13.77 | 5,075 | 5,075 | |||||
| 2020-01-09 | 2020-01-09 | 4 | Hemrajani Rekha | ARAV | Stock Options | D | 13.77 | 143,000 | 143,000 | |||||
| 2020-01-09 | 2020-01-09 | 4 | Hemrajani Rekha | ARAV | Common Stock | D | 57,000 | 57,000 | ||||||
| 2019-12-26 | 2019-12-20 | 4 | Shepard Jay | ARAV | Common Stock | D | 11.6700 | -2,262 | -26 | 70,492 | ||||
| 2019-12-02 | 2019-12-02 | 4 | AKKARAJU SRINIVAS | ARAV | Common Stock | I | 7.5000 | 133,333 | 1,000 | 576,066 | ||||
| 2019-10-08 | 2019-10-07 | 4 | Shepard Jay | ARAV | Common Stock | D | 6.8170 | -4,004 | -27 | 72,754 | ||||
| 2019-09-13 | 2019-09-12 | 4 | Malik Shahzad | ARAV | Stock Option | D | 5.77 | 7,500 | 7,500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | AKKARAJU SRINIVAS | ARAV | Stock Option | D | 5.77 | 7,500 | 7,500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 5.77 | 7,500 | 7,500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | Giaccia Amato | ARAV | Stock Option | D | 5.77 | 7,500 | 7,500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | HOFFMAN ROBERT | ARAV | Stock Option | D | 5.77 | 7,500 | 7,500 | |||||
| 2019-09-13 | 2019-09-12 | 4 | Zhang Eric | ARAV | Stock Option | D | 5.77 | 7,500 | 7,500 | |||||
| 2019-05-13 | 2019-05-10 | 4 | Shepard Jay | ARAV | Common Stock | D | 6.1100 | -1,192 | -7 | 76,758 | ||||
| 2019-03-04 | 2019-02-28 | 4 | McIntyre Gail Frances | ARAV | Stock Option | D | 5.83 | 53,000 | 53,000 | |||||
| 2019-03-04 | 2019-02-28 | 4 | Shepard Jay | ARAV | Stock Option | D | 5.83 | 116,000 | 116,000 | |||||
| 2019-03-04 | 2019-02-28 | 4 | Haas Kevin | ARAV | Stock Option | D | 5.83 | 18,000 | 18,000 | |||||
| 2019-03-04 | 2019-02-28 | 4 | Shah Vinay | ARAV | Stock Option | D | 5.83 | 38,000 | 38,000 | |||||
| 2019-02-05 | 2019-02-01 | 4 | Haas Kevin | ARAV | Common Stock | D | 4.1400 | -63 | -0 | 10,933 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Haas Kevin | ARAV | Common Stock | D | 4.1400 | -141 | -1 | 10,996 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Shepard Jay | ARAV | Common Stock | D | 4.1400 | -990 | -4 | 81,950 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Shepard Jay | ARAV | Common Stock | D | 4.1400 | -969 | -4 | 82,940 | ||||
| 2019-02-05 | 2019-02-01 | 4 | Shepard Jay | ARAV | Common Stock | D | 4.1400 | -204 | -1 | 83,909 | ||||
| 2019-01-07 | 2019-01-03 | 4/A | Malik Shahzad | ARAV | Stock Option | D | 3.61 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | HOFFMAN ROBERT | ARAV | Stock Option | D | 3.61 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | HOFFMAN ROBERT | ARAV | Stock Option | D | 3.61 | 7,500 | 7,500 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | Giaccia Amato | ARAV | Stock Option | D | 3.61 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | Giaccia Amato | ARAV | Stock Option | D | 3.61 | 7,500 | 7,500 | |||||
| 2019-01-07 | 2019-01-03 | 4/A | AKKARAJU SRINIVAS | ARAV | Stock Option | D | 3.61 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Malik Shahzad | ARAV | Stock Option | D | 3.69 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | AKKARAJU SRINIVAS | ARAV | Stock Option | D | 3.69 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Giaccia Amato | ARAV | Stock Option | D | 3.69 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Giaccia Amato | ARAV | Stock Option | D | 3.69 | 7,500 | 7,500 | |||||
| 2019-01-07 | 2019-01-03 | 4 | HOFFMAN ROBERT | ARAV | Stock Option | D | 3.69 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | HOFFMAN ROBERT | ARAV | Stock Option | D | 3.69 | 7,500 | 7,500 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 3.61 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Tabibiazar Raymond | ARAV | Stock Option | D | 3.61 | 7,500 | 7,500 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Zhang Eric | ARAV | Stock Option | D | 3.61 | 4,688 | 4,688 | |||||
| 2019-01-07 | 2019-01-03 | 4 | Zhang Eric | ARAV | Stock Option | D | 3.61 | 7,500 | 7,500 | |||||
| 2018-12-26 | 2018-12-21 | 4 | Haas Kevin | ARAV | Common Stock | D | 3.2300 | -25 | -0 | 11,137 | ||||
| 2018-12-26 | 2018-12-21 | 4 | Haas Kevin | ARAV | Common Stock | D | 3.2170 | -686 | -2 | 11,162 | ||||
| 2018-12-26 | 2018-12-21 | 4 | Shepard Jay | ARAV | Common Stock | D | 3.2240 | -3,484 | -11 | 84,113 | ||||
| 2018-12-19 | 2018-12-17 | 4 | Haas Kevin | ARAV | Common Stock | D | 3.9620 | -1,164 | -5 | 11,848 | ||||
| 2018-12-19 | 2018-12-17 | 4 | Shepard Jay | ARAV | Common Stock | D | 3.9620 | -11,247 | -45 | 87,597 | ||||
| 2018-10-16 | 2018-10-12 | 4 | Zhang Eric | ARAV | Common Stock | I | 859,766 | 859,766 | ||||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.90 | 28,501 | 28,501 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.90 | 28,501 | 28,501 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.66 | 57,002 | 57,002 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 15,200 | 15,200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 15,200 | 15,200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 15,200 | 15,200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 15,200 | 15,200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 254,177 | 254,177 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 65,365 | 65,365 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 15,200 | 15,200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 15,200 | 15,200 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.24 | 51,682 | 51,682 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.06 | 12,084 | 12,084 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Stock Option (Right to Buy) | D | 0.06 | 46,322 | 46,322 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Tabibiazar Raymond | ARAV | Common Stock | D | 1,000,751 | 1,000,751 | ||||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0.90 | 19,000 | 19,000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0.90 | 19,000 | 19,000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0.66 | 38,001 | 38,001 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Stock Option (Right to Buy) | D | 0.24 | 19,380 | 19,380 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Shah Vinay | ARAV | Common Stock | D | 178,606 | 178,606 | ||||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.90 | 19,000 | 19,000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (RIght to Buy) | D | 0.90 | 19,000 | 19,000 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.66 | 38,001 | 38,001 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 9,120 | 9,120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 9,120 | 9,120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 9,120 | 9,120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 9,120 | 9,120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 26,813 | 26,813 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 9,120 | 9,120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 9,120 | 9,120 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.24 | 38,761 | 38,761 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.06 | 12,350 | 12,350 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.06 | 4,028 | 4,028 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Stock Option (Right to Buy) | D | 0.06 | 8,055 | 8,055 | |||||
| 2018-10-16 | 2018-10-12 | 4 | Giaccia Amato | ARAV | Common Stock | D | 941,880 | 941,880 | ||||||
| 2018-10-16 | 3 | Zhang Eric | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 3 | Shah Vinay | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 3 | Tabibiazar Raymond | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 3 | Giaccia Amato | ARAV | Common Stock | D | 0 | ||||||||
| 2018-10-16 | 2018-10-12 | 4 | AKKARAJU SRINIVAS | ARAV | Common Stock | D | 27,456 | 31,815 | ||||||
| 2018-10-16 | 3 | HOFFMAN ROBERT | ARAV | Common Stock | D | 0 | ||||||||
| 2018-06-19 | 2018-06-15 | 4 | Haas Kevin | VSAR | Common Stock | D | 2.3000 | -143 | -0 | 78,075 | ||||
| 2018-06-19 | 2018-06-15 | 4 | Westberg Paul | VSAR | Common Stock | D | 2.3000 | -612 | -1 | 225,124 | ||||
| 2018-06-15 | 2018-06-13 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2.1300 | 53,018 | 113 | 2,682,554 | ||||
| 2018-06-08 | 2018-06-08 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2.0000 | 231,580 | 463 | 2,629,536 | ||||
| 2018-06-08 | 2018-06-07 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 1.8500 | 163,224 | 302 | 2,397,956 | ||||
| 2018-06-08 | 2018-06-06 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 1.7400 | 660,681 | 1,150 | 2,234,732 | ||||
| 2018-05-23 | 2018-05-22 | 4 | Shepard Jay | VSAR | Common Stock | D | 1.5000 | -9,232 | -14 | 593,066 | ||||
| 2018-04-25 | 2018-04-24 | 4 | Stout Jay S | VSAR | Common Stock | D | 1.5500 | -4,854 | -8 | 185,646 | ||||
| 2018-03-26 | 2018-03-23 | 4 | Woody Tracy M | VSAR | Common Stock | D | 1.7500 | -4,345 | -8 | 215,755 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.8000 | -5,355 | -10 | 225,736 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Ward Shane | VSAR | Common Stock | D | 1.8000 | -4,118 | -7 | 201,556 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Shepard Jay | VSAR | Common Stock | D | 1.8000 | -14,446 | -26 | 602,298 | ||||
| 2018-02-12 | 2018-02-08 | 4 | Haas Kevin | VSAR | Common Stock | D | 1.8000 | -1,599 | -3 | 78,218 | ||||
| 2017-12-22 | 2017-12-20 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 11,200 | 44,380 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Gut Robert | VSAR | Common Stock | D | 91,300 | 227,300 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Haas Kevin | VSAR | Common Stock | D | 44,700 | 79,817 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 11,200 | 22,380 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Malik Shahzad | VSAR | Common Stock | D | 11,200 | 23,880 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Shepard Jay | VSAR | Common Stock | D | 223,000 | 616,744 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Stout Jay S | VSAR | Common Stock | D | 74,500 | 190,500 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 11,200 | 23,880 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Varian John | VSAR | Common Stock | D | 11,200 | 22,280 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Ward Shane | VSAR | Common Stock | D | 93,100 | 205,674 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Westberg Paul | VSAR | Common Stock | D | 90,900 | 231,091 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | Woody Tracy M | VSAR | Common Stock | D | 93,100 | 220,100 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 11,200 | 26,155 | ||||||
| 2017-12-22 | 2017-12-20 | 4 | DOBMEIER ERIC | VSAR | Common Stock | D | 11,200 | 18,160 | ||||||
| 2017-12-05 | 2017-12-05 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2.0000 | 42,895 | 86 | 1,547,896 | ||||
| 2017-12-05 | 2017-12-04 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2.2100 | 513,872 | 1,136 | 1,505,001 | ||||
| 2017-12-05 | 2017-12-01 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 2.1300 | 419,700 | 894 | 991,129 | ||||
| 2017-12-04 | 3 | Haas Kevin | VSAR | Common Stock | D | 70,234 | ||||||||
| 2017-12-04 | 3 | Haas Kevin | VSAR | Common Stock | D | 70,234 | ||||||||
| 2017-11-29 | 2017-11-28 | 4 | Ward Shane | VSAR | Common Stock | D | 20,000 | 112,574 | ||||||
| 2017-11-29 | 2017-11-28 | 4 | Westberg Paul | VSAR | Common Stock | D | 15,000 | 140,191 | ||||||
| 2017-10-23 | 2017-10-19 | 4 | Westberg Paul | VSAR | Common Stock | D | 2.5500 | -1,326 | -3 | 125,191 | ||||
| 2017-10-23 | 2017-10-19 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 2.5500 | -1,326 | -3 | 201,269 | ||||
| 2017-10-23 | 2017-10-19 | 4 | Hislop Colin | VSAR | Common Stock | D | 2.5500 | -667 | -2 | 23,833 | ||||
| 2017-10-23 | 2017-10-19 | 4 | Ward Shane | VSAR | Common Stock | D | 2.5500 | -776 | -2 | 92,574 | ||||
| 2017-10-10 | 2017-10-06 | 4 | Shepard Jay | VSAR | Common Stock | D | 189,000 | 393,744 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Stout Jay S | VSAR | Common Stock | D | 70,000 | 116,000 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Ward Shane | VSAR | Common Stock | D | 57,000 | 93,350 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 59,000 | 126,517 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Woody Tracy M | VSAR | Common Stock | D | 82,000 | 127,000 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 97,000 | 202,595 | ||||||
| 2017-10-10 | 2017-10-06 | 4 | Gut Robert | VSAR | Common Stock | D | 88,000 | 136,000 | ||||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3.3500 | -350,000 | -1,172 | 2,099,563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3.2665 | -500,000 | -1,633 | 2,449,563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3.1700 | -250,000 | -792 | 2,949,563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3.0290 | -250,000 | -757 | 3,199,563 | ||||
| 2017-09-25 | 2017-09-22 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3.0875 | -300,000 | -926 | 3,449,563 | ||||
| 2017-09-25 | 2017-09-21 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3.5599 | -353,421 | -1,258 | 3,749,563 | ||||
| 2017-09-25 | 2017-09-21 | 4 | PERCEPTIVE ADVISORS LLC | VSAR | Common Stock | I | 3.7420 | -126,579 | -474 | 4,102,984 | ||||
| 2017-09-06 | 3 | Gut Robert | VSAR | No securities held. | D | 0 | ||||||||
| 2017-09-06 | 2017-09-05 | 4 | Gut Robert | VSAR | Stock Option (Right to Buy) | D | 19.80 | 107,000 | 107,000 | |||||
| 2017-09-06 | 2017-09-05 | 4 | Gut Robert | VSAR | Common Stock | D | 48,000 | 48,000 | ||||||
| 2017-06-14 | 2017-06-13 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 16.0500 | -1,421 | -23 | 105,595 | ||||
| 2017-06-14 | 2017-06-13 | 4 | Westberg Paul | VSAR | Common Stock | D | 16.0500 | -711 | -11 | 67,517 | ||||
| 2017-06-06 | 3 | DOBMEIER ERIC | VSAR | Common Stock | D | 0 | ||||||||
| 2017-06-06 | 2017-05-25 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 3,480 | 11,180 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | GREER R SCOTT | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 3,480 | 33,180 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 3,480 | 14,955 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Common Stock | D | 3,480 | 6,960 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | DOBMEIER ERIC | VSAR | Common Stock | D | 3,480 | 6,960 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | Varian John | VSAR | Common Stock | D | 3,480 | 11,080 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 3,480 | 12,680 | ||||||
| 2017-06-06 | 2017-05-25 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 15.82 | 6,850 | 6,850 | |||||
| 2017-06-06 | 2017-05-25 | 4 | Malik Shahzad | VSAR | Common Stock | D | 3,480 | 12,680 | ||||||
| 2017-05-17 | 2017-05-16 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 17.4000 | -1,263 | -22 | 107,016 | ||||
| 2017-05-15 | 2017-05-11 | 4 | Shepard Jay | VSAR | Common Stock | D | 17.5000 | -9,114 | -159 | 204,744 | ||||
| 2017-04-20 | 2017-04-19 | 4 | Westberg Paul | VSAR | Common Stock | D | 19.8500 | -1,316 | -26 | 68,228 | ||||
| 2017-04-05 | 3 | Stout Jay S | VSAR | Common Stock | D | 2,000 | ||||||||
| 2017-04-05 | 3 | Stout Jay S | VSAR | Common Stock | D | 2,000 | ||||||||
| 2017-04-05 | 2017-04-03 | 4 | Stout Jay S | VSAR | Stock Option (Right to Buy) | D | 21.30 | 75,000 | 75,000 | |||||
| 2017-04-05 | 2017-04-03 | 4 | Stout Jay S | VSAR | Common Stock | D | 45,000 | 46,000 | ||||||
| 2017-04-05 | 2017-04-04 | 4 | Hislop Colin | VSAR | Stock Option (Right to Buy) | D | 8.17 | -35,000 | 188,100 | |||||
| 2017-04-05 | 2017-04-04 | 4 | Hislop Colin | VSAR | Common Stock | D | 21.2000 | -35,000 | -742 | 24,500 | ||||
| 2017-04-05 | 2017-04-04 | 4 | Hislop Colin | VSAR | Common Stock | D | 8.1700 | 35,000 | 286 | 59,500 | ||||
| 2017-03-31 | 3 | Woody Tracy M | VSAR | Common Stock | D | 0 | ||||||||
| 2017-03-31 | 2017-03-22 | 4 | Woody Tracy M | VSAR | Stock Option (Right to Buy) | D | 20.15 | 100,000 | 100,000 | |||||
| 2017-03-31 | 2017-03-22 | 4 | Woody Tracy M | VSAR | Common Stock | D | 45,000 | 45,000 | ||||||
| 2017-03-28 | 2017-03-24 | 4 | AKKARAJU SRINIVAS By Partnership | VSAR | Common Stock | I | 12.2500 | 571,429 | 7,000 | 571,429 | ||||
| 2017-03-17 | 2017-03-17 | 4 | Malik Shahzad | VSAR | Common Stock | I | 18.0100 | -386,367 | -6,958 | 1,621,558 | ||||
| 2017-03-17 | 2017-03-16 | 4 | Malik Shahzad | VSAR | Common Stock | I | 18.5000 | -97,303 | -1,800 | 2,007,925 | ||||
| 2017-03-15 | 2017-03-15 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19.0800 | -103,122 | -1,968 | 2,105,228 | ||||
| 2017-03-15 | 2017-03-14 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19.0000 | -46,778 | -889 | 2,208,350 | ||||
| 2017-03-15 | 2017-03-14 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19.0300 | -100 | -2 | 2,255,128 | ||||
| 2017-03-15 | 2017-03-13 | 4 | Malik Shahzad | VSAR | Common Stock | I | 19.4200 | -16,330 | -317 | 2,255,228 | ||||
| 2017-03-15 | 2017-03-15 | 4 | Ward Shane | VSAR | Common Stock | D | 19.0200 | -776 | -15 | 36,350 | ||||
| 2017-03-15 | 2017-03-14 | 4 | Ward Shane | VSAR | Common Stock | D | 19.0000 | -1,265 | -24 | 37,126 | ||||
| 2017-03-14 | 2017-02-13 | 4/A | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 15.5146 | 59,133 | 917 | 4,229,563 | ||||
| 2017-03-14 | 2017-02-10 | 4/A | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14.9437 | 34,883 | 521 | 4,170,430 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 2.53 | -30,000 | 122,108 | |||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 22.0500 | -5,653 | -125 | 105,779 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 21.4600 | -6,008 | -129 | 111,432 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 20.4200 | -18,339 | -374 | 117,440 | ||||
| 2017-02-28 | 2017-02-24 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 2.5300 | 30,000 | 76 | 135,779 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2.53 | -5,166 | 65,828 | |||||
| 2017-02-28 | 2017-02-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 24.0000 | -5,166 | -124 | 213,858 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 2.5300 | 5,166 | 13 | 219,024 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 2.53 | -4,991 | 7,491 | |||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.61 | -7,509 | 2,975 | |||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 22.5000 | -12,500 | -281 | 69,544 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 2.5300 | 4,991 | 13 | 82,044 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.6100 | 7,509 | 12 | 77,053 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.61 | -6,590 | 10,484 | |||||
| 2017-02-23 | 2017-02-23 | 4 | Westberg Paul | VSAR | Common Stock | D | 20.0000 | -6,590 | -132 | 69,544 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.6100 | 6,590 | 11 | 76,134 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.61 | -3,323 | 17,074 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.61 | -15,087 | 506 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 20.0000 | -5,910 | -118 | 69,544 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 17.5000 | -12,500 | -219 | 75,454 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.6100 | 18,410 | 30 | 87,954 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2.53 | -8,000 | 70,994 | |||||
| 2017-02-23 | 2017-02-23 | 4 | Shepard Jay | VSAR | Common Stock | D | 20.0000 | -8,000 | -160 | 213,858 | ||||
| 2017-02-23 | 2017-02-23 | 4 | Shepard Jay | VSAR | Common Stock | D | 2.5300 | 8,000 | 20 | 221,858 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2.53 | -8,000 | 78,994 | |||||
| 2017-02-23 | 2017-02-21 | 4 | Shepard Jay | VSAR | Common Stock | D | 18.5000 | -8,000 | -148 | 213,858 | ||||
| 2017-02-23 | 2017-02-21 | 4 | Shepard Jay | VSAR | Common Stock | D | 2.5300 | 8,000 | 20 | 221,858 | ||||
| 2017-02-14 | 2017-02-13 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 15.5146 | 59,133 | 917 | 4,228,563 | ||||
| 2017-02-14 | 2017-02-10 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14.9437 | 34,883 | 521 | 4,169,430 | ||||
| 2017-02-10 | 2017-02-09 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14.2663 | 41,211 | 588 | 4,134,547 | ||||
| 2017-02-10 | 2017-02-08 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 13.5101 | 104,612 | 1,413 | 4,093,336 | ||||
| 2017-02-06 | 2017-02-03 | 4 | Shepard Jay | VSAR | Common Stock | D | 13.6900 | -6,719 | -92 | 213,858 | ||||
| 2017-02-02 | 2017-02-02 | 4 | Shepard Jay | VSAR | Common Stock | D | 13.5100 | -6,973 | -94 | 220,577 | ||||
| 2017-02-02 | 2017-02-02 | 4 | Shepard Jay | VSAR | Common Stock | D | 2.5300 | 4,166 | 11 | 227,550 | ||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2.53 | -4,166 | 86,994 | |||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2.53 | -6,576 | 91,160 | |||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Common Stock | D | 13.9500 | -6,576 | -92 | 223,384 | ||||
| 2017-02-02 | 2017-02-01 | 4 | Shepard Jay | VSAR | Common Stock | D | 2.5300 | 6,576 | 17 | 229,960 | ||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2.53 | -10,662 | 97,736 | |||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Common Stock | D | 14.1600 | -5,940 | -84 | 223,384 | ||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Common Stock | D | 13.4000 | -4,722 | -63 | 229,324 | ||||
| 2017-02-02 | 2017-01-31 | 4 | Shepard Jay | VSAR | Common Stock | D | 2.5300 | 10,662 | 27 | 234,046 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Hislop Colin | VSAR | Stock Option (Right to Buy) | D | 14.30 | 43,700 | 43,700 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Hislop Colin | VSAR | Common Stock | D | 19,500 | 24,500 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 13.8520 | -2,945 | -41 | 105,779 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 14.30 | 65,590 | 65,590 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 43,900 | 108,724 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 2.53 | -10,596 | 108,398 | |||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Common Stock | D | 13.3100 | -10,596 | -141 | 223,384 | ||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Common Stock | D | 2.5300 | 10,596 | 27 | 233,980 | ||||
| 2017-01-31 | 2017-01-30 | 4 | Shepard Jay | VSAR | Common Stock | D | 13.8500 | -6,674 | -92 | 223,384 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 14.30 | 144,900 | 144,900 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 10,000 | 230,058 | ||||||
| 2017-01-31 | 2017-01-27 | 4 | Shepard Jay | VSAR | Common Stock | D | 64,700 | 220,058 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Westberg Paul | VSAR | Common Stock | D | 13.8520 | -1,916 | -27 | 69,544 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 14.30 | 40,130 | 40,130 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 26,860 | 71,460 | ||||||
| 2017-01-31 | 2017-01-30 | 4 | Ward Shane | VSAR | Common Stock | D | 13.8520 | -1,474 | -20 | 38,391 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Ward Shane | VSAR | Stock Option (Right to Buy) | D | 14.30 | 46,200 | 46,200 | |||||
| 2017-01-31 | 2017-01-27 | 4 | Ward Shane | VSAR | Common Stock | D | 20,600 | 39,865 | ||||||
| 2017-01-11 | 2017-01-11 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.61 | -7,931 | 15,593 | |||||
| 2017-01-11 | 2017-01-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 15.2400 | -7,931 | -121 | 44,600 | ||||
| 2017-01-11 | 2017-01-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.6100 | 7,931 | 13 | 52,531 | ||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.61 | -746 | 23,524 | |||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.38 | -10,467 | 0 | |||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Common Stock | D | 15.6600 | -11,213 | -176 | 44,600 | ||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.6100 | 746 | 1 | 55,813 | ||||
| 2017-01-11 | 2017-01-10 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.3800 | 10,467 | 14 | 55,067 | ||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.38 | -11,044 | 10,467 | |||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -2,312 | 0 | |||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Common Stock | D | 15.9300 | -13,356 | -213 | 44,600 | ||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.3800 | 11,044 | 15 | 57,956 | ||||
| 2017-01-11 | 2017-01-09 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 2,312 | 3 | 46,912 | ||||
| 2017-01-04 | 2016-12-30 | 4/A | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14.6580 | 71,063 | 1,042 | 3,989,724 | ||||
| 2017-01-04 | 2016-12-30 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14.6580 | 94,750 | 1,389 | 4,013,411 | ||||
| 2016-12-30 | 2016-12-29 | 4 | PERCEPTIVE ADVISORS LLC See Footnotes | VSAR | Common Stock | I | 14.3660 | 47,375 | 681 | 3,918,661 | ||||
| 2016-12-29 | 2016-12-27 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 15.8500 | -990 | -16 | 64,824 | ||||
| 2016-12-29 | 2016-12-27 | 4 | Westberg Paul | VSAR | Common Stock | D | 15.8500 | -361 | -6 | 44,600 | ||||
| 2016-12-19 | 2016-12-16 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -5,000 | 2,312 | |||||
| 2016-12-19 | 2016-12-16 | 4 | Westberg Paul | VSAR | Common Stock | D | 15.0000 | -5,000 | -75 | 44,961 | ||||
| 2016-12-19 | 2016-12-16 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 5,000 | 6 | 49,961 | ||||
| 2016-12-08 | 2016-12-08 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 12.9550 | -1,500 | -19 | 7,700 | ||||
| 2016-12-08 | 2016-12-07 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 13.2500 | -3,021 | -40 | 65,814 | ||||
| 2016-10-13 | 2016-10-11 | 4 | Hislop Colin | VSAR | Common Stock | D | 5,000 | 5,000 | ||||||
| 2016-10-13 | 2016-10-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10,000 | 68,835 | ||||||
| 2016-10-13 | 2016-10-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 10,000 | 44,961 | ||||||
| 2016-10-13 | 2016-10-11 | 4 | Ward Shane | VSAR | Common Stock | D | 5,000 | 19,265 | ||||||
| 2016-10-05 | 3/A | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 3,871,286 | ||||||||
| 2016-10-04 | 2016-10-03 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | I | 12.2500 | 571,429 | 7,000 | 571,429 | ||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7,594,838 | ||||||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7,594,838 | ||||||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7,594,838 | ||||||||
| 2016-09-28 | 3 | EDELMAN JOSEPH See Footnotes | VSAR | Common Stock | I | 7,594,838 | ||||||||
| 2016-08-26 | 2016-08-25 | 4 | Varian John | VSAR | Common Stock | D | 12.9718 | -1,600 | -21 | 7,600 | ||||
| 2016-08-24 | 2016-08-22 | 4 | Shepard Jay | VSAR | Common Stock | D | 12.8800 | -5,442 | -70 | 155,358 | ||||
| 2016-06-20 | 2016-06-14 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 10.87 | 28,720 | 28,720 | |||||
| 2016-06-20 | 2016-06-14 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 6,900 | 11,475 | ||||||
| 2016-06-17 | 2016-06-15 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10.6300 | -1,448 | -15 | 58,835 | ||||
| 2016-06-17 | 2016-06-15 | 4 | Westberg Paul | VSAR | Common Stock | D | 10.6300 | -725 | -8 | 34,961 | ||||
| 2016-05-20 | 2016-05-18 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 8.12 | 14,625 | 14,625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | Varian John | VSAR | Common Stock | D | 4,625 | 9,200 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 8.12 | 14,625 | 14,625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 4,625 | 9,200 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 8.12 | 14,625 | 14,625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 4,625 | 9,200 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | GREER R SCOTT | VSAR | Stock Option (Right to Buy) | D | 8.12 | 14,625 | 14,625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 4,625 | 29,700 | ||||||
| 2016-05-20 | 2016-05-18 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 8.12 | 14,625 | 14,625 | |||||
| 2016-05-20 | 2016-05-18 | 4 | Malik Shahzad | VSAR | Common Stock | D | 4,625 | 9,200 | ||||||
| 2016-05-20 | 2016-05-20 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 7.8700 | -1,265 | -10 | 60,283 | ||||
| 2016-05-02 | 3 | Hislop Colin | VSAR | Common Stock | D | 0 | ||||||||
| 2016-05-02 | 2016-04-04 | 4 | Hislop Colin | VSAR | Stock Option (Right to Buy) | D | 8.17 | 223,100 | 223,100 | |||||
| 2016-04-25 | 2016-04-21 | 4 | Westberg Paul | VSAR | Common Stock | D | 9.6800 | -1,430 | -14 | 35,686 | ||||
| 2016-02-01 | 2016-01-28 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 10.68 | 83,800 | 83,800 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 26,000 | 61,548 | ||||||
| 2016-02-01 | 2016-01-28 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 10.68 | 54,400 | 54,400 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Westberg Paul | VSAR | Common Stock | D | 16,900 | 37,116 | ||||||
| 2016-02-01 | 2016-01-28 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 10.68 | 209,200 | 209,200 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Shepard Jay | VSAR | Common Stock | D | 64,800 | 160,800 | ||||||
| 2016-02-01 | 2016-01-28 | 4 | Ward Shane | VSAR | Stock Option (Right to Buy) | D | 10.68 | 42,000 | 42,000 | |||||
| 2016-02-01 | 2016-01-28 | 4 | Ward Shane | VSAR | Common Stock | D | 13,000 | 14,265 | ||||||
| 2016-01-04 | 2015-12-30 | 4 | Westberg Paul | VSAR | Common Stock | D | 12.4360 | -362 | -5 | 20,216 | ||||
| 2016-01-04 | 2015-12-30 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 12.4360 | -990 | -12 | 35,548 | ||||
| 2015-11-13 | 2015-11-12 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 9.9900 | 2,500 | 25 | 36,538 | ||||
| 2015-11-13 | 2015-11-11 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 10.1700 | 9,500 | 97 | 25,075 | ||||
| 2015-11-13 | 2015-11-11 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 10.1600 | 200 | 2 | 15,575 | ||||
| 2015-11-13 | 2015-11-11 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 10.1500 | 300 | 3 | 15,375 | ||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -2,400 | 7,312 | |||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 18.5300 | -142 | -3 | 20,578 | ||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 18.2500 | -2,258 | -41 | 20,720 | ||||
| 2015-08-05 | 2015-08-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 2,400 | 3 | 22,978 | ||||
| 2015-07-07 | 2015-07-06 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -2,400 | 9,712 | |||||
| 2015-07-07 | 2015-07-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 15.0000 | -2,400 | -36 | 20,578 | ||||
| 2015-07-07 | 2015-07-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 2,400 | 3 | 22,978 | ||||
| 2015-07-01 | 2015-06-29 | 4 | GREER R SCOTT | VSAR | Stock Option (Right to Buy) | D | 14.73 | 13,100 | 13,100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 4,575 | 15,075 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 14.73 | 13,100 | 13,100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | JENNINGS EDMON R | VSAR | Common Stock | D | 4,575 | 4,575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 14.73 | 13,100 | 13,100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 4,575 | 4,575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 14.73 | 13,100 | 13,100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | SUN ANTHONY Y | VSAR | Common Stock | D | 4,575 | 4,575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 14.73 | 13,100 | 13,100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | Varian John | VSAR | Common Stock | D | 4,575 | 4,575 | ||||||
| 2015-07-01 | 2015-06-29 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 14.73 | 13,100 | 13,100 | |||||
| 2015-07-01 | 2015-06-29 | 4 | Malik Shahzad | VSAR | Common Stock | D | 4,575 | 4,575 | ||||||
| 2015-06-15 | 2015-06-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 17.2800 | -1,375 | -24 | 34,038 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 19.9000 | -1,222 | -24 | 35,413 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 17.2800 | -687 | -12 | 20,578 | ||||
| 2015-06-15 | 2015-06-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 19.9000 | -1,222 | -24 | 21,265 | ||||
| 2015-06-04 | 2015-06-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -2,400 | 12,112 | |||||
| 2015-06-04 | 2015-06-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 16.7259 | -2,400 | -40 | 22,487 | ||||
| 2015-06-04 | 2015-06-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 2,400 | 3 | 24,887 | ||||
| 2015-05-13 | 2015-05-11 | 4 | Shepard Jay | VSAR | Stock Option (Right to Buy) | D | 15.19 | 309,000 | 309,000 | |||||
| 2015-05-13 | 2015-05-11 | 4 | Shepard Jay | VSAR | Common Stock | D | 96,000 | 96,000 | ||||||
| 2015-05-06 | 2015-05-04 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -2,400 | 14,512 | |||||
| 2015-05-06 | 2015-05-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 17.4706 | -2,400 | -42 | 22,487 | ||||
| 2015-05-06 | 2015-05-04 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 2,400 | 3 | 24,887 | ||||
| 2015-04-16 | 2014-12-22 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | 21.3561 | -5,870 | -125 | 133,388 | ||||
| 2015-04-16 | 2014-12-22 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | 20.5364 | -2,110 | -43 | 139,258 | ||||
| 2015-04-16 | 2014-12-19 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0000 | -20 | -0 | 141,368 | ||||
| 2015-04-16 | 2014-11-14 | 4/A | Cleland Jeffrey L | VSAR | Common Stock | D | -1,900 | 141,388 | ||||||
| 2015-04-16 | 2014-12-15 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 496 | 142,396 | ||||||
| 2015-04-16 | 2015-04-14 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.1300 | -8,000 | -161 | 121,548 | ||||
| 2015-04-08 | 3 | Ward Shane | VSAR | Common Stock | D | 0 | ||||||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -2,041 | 16,912 | |||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -359 | 0 | |||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 17.4884 | -2,400 | -42 | 22,487 | ||||
| 2015-04-08 | 2015-04-06 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 2,400 | 3 | 24,887 | ||||
| 2015-04-08 | 2015-04-06 | 4 | Ward Shane | VSAR | Stock Option (Right to Buy) | D | 17.47 | 50,000 | 50,000 | |||||
| 2015-03-24 | 2015-03-23 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.2573 | -4,000 | -81 | 93,432 | ||||
| 2015-03-20 | 2015-03-20 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0670 | -740 | -15 | 97,432 | ||||
| 2015-03-20 | 2015-03-19 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0086 | -1,315 | -26 | 98,172 | ||||
| 2015-03-20 | 2015-03-18 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0309 | -1,124 | -23 | 99,487 | ||||
| 2015-03-17 | 2015-03-17 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0908 | -738 | -15 | 100,611 | ||||
| 2015-03-17 | 2015-03-16 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0300 | -3 | -0 | 101,349 | ||||
| 2015-03-17 | 2015-03-16 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0100 | -80 | -2 | 101,352 | ||||
| 2015-03-11 | 2015-03-10 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.3003 | -2,537 | -52 | 101,432 | ||||
| 2015-03-11 | 2015-03-09 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.1034 | -1,463 | -29 | 103,969 | ||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -2,041 | 18,953 | |||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -359 | 359 | |||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 20.0292 | -2,400 | -48 | 22,487 | ||||
| 2015-03-05 | 2015-03-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 2,400 | 3 | 24,887 | ||||
| 2015-03-05 | 2015-03-03 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0689 | -1,129 | -23 | 105,432 | ||||
| 2015-03-02 | 2015-03-02 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.1144 | -2,871 | -58 | 106,561 | ||||
| 2015-02-27 | 2015-02-25 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.2471 | -8,000 | -162 | 109,432 | ||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -3,501 | 20,994 | |||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -1,499 | 718 | |||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 18.0984 | -371 | -7 | 22,487 | ||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 17.3408 | -4,629 | -80 | 22,858 | ||||
| 2015-02-04 | 2015-02-03 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 5,000 | 6 | 27,487 | ||||
| 2015-01-29 | 2015-01-27 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 17.2500 | 145,000 | 2,501 | 2,139,568 | ||||
| 2015-01-29 | 2015-01-27 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 17.2500 | 145,000 | 2,501 | 2,139,568 | ||||
| 2015-01-27 | 2015-01-27 | 4 | GREER R SCOTT | VSAR | Common Stock | D | 17.2500 | 5,500 | 95 | 10,500 | ||||
| 2015-01-26 | 2015-01-22 | 4/A | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 17.2500 | 55,000 | 949 | 2,271,558 | ||||
| 2015-01-26 | 2015-01-22 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 17.2500 | 55,000 | 949 | 2,271,558 | ||||
| 2015-01-26 | 2015-01-22 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 17.2500 | 55,000 | 949 | 2,271,558 | ||||
| 2015-01-13 | 2015-01-12 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 22.8545 | -4,000 | -91 | 117,432 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -5,000 | 2,217 | |||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Common Stock | D | 23.3347 | -1,270 | -30 | 22,487 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Common Stock | D | 22.1893 | -3,730 | -83 | 23,757 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 5,000 | 6 | 27,487 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 21.9692 | -3,800 | -83 | 121,432 | ||||
| 2015-01-07 | 2015-01-05 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 21.2900 | -200 | -4 | 125,232 | ||||
| 2014-12-30 | 2014-12-26 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 22.24 | 8,860 | 8,860 | |||||
| 2014-12-30 | 2014-12-26 | 4 | Westberg Paul | VSAR | Common Stock | D | 3,797 | 22,487 | ||||||
| 2014-12-30 | 2014-12-26 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 22.24 | 24,373 | 24,373 | |||||
| 2014-12-30 | 2014-12-26 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10,445 | 36,635 | ||||||
| 2014-12-30 | 2014-12-29 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 22.1054 | -4,000 | -88 | 125,432 | ||||
| 2014-12-30 | 2014-12-26 | 4 | Cleland Jeffrey L | VSAR | Stock Option (Right to Buy) | D | 22.24 | 75,041 | 75,041 | |||||
| 2014-12-30 | 2014-12-26 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 32,160 | 129,432 | ||||||
| 2014-12-22 | 2014-12-22 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 21.3561 | -5,870 | -125 | 97,272 | ||||
| 2014-12-22 | 2014-12-22 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.5364 | -2,110 | -43 | 103,142 | ||||
| 2014-12-22 | 2014-12-19 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 20.0000 | -20 | -0 | 105,252 | ||||
| 2014-12-22 | 2014-11-14 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | -1,900 | 105,272 | ||||||
| 2014-12-22 | 2014-12-18 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 19.0123 | -150,000 | -2,852 | 2,409,374 | ||||
| 2014-12-15 | 2014-12-12 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -3,054 | 7,217 | |||||
| 2014-12-15 | 2014-12-12 | 4 | Westberg Paul | VSAR | Common Stock | D | 18.6542 | -3,054 | -57 | 18,690 | ||||
| 2014-12-15 | 2014-12-12 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 3,054 | 4 | 21,744 | ||||
| 2014-12-15 | 2014-12-11 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 1.26 | -6,946 | 10,271 | |||||
| 2014-12-15 | 2014-12-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 18.5100 | -6,946 | -129 | 18,690 | ||||
| 2014-12-15 | 2014-12-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 1.2650 | 6,946 | 9 | 25,636 | ||||
| 2014-12-11 | 3 | GREER R SCOTT | VSAR | Common Stock | D | 10,000 | ||||||||
| 2014-12-11 | 3 | GREER R SCOTT | VSAR | Common Stock | D | 10,000 | ||||||||
| 2014-12-11 | 2014-12-09 | 4 | GREER R SCOTT | VSAR | Stock Option (right to Buy) | D | 18.66 | 35,000 | 35,000 | |||||
| 2014-11-25 | 2014-11-24 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.0164 | -138 | -2 | 19,161 | ||||
| 2014-11-25 | 2014-11-24 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.0164 | -1,480 | -27 | 205,968 | ||||
| 2014-11-25 | 2014-11-24 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.0164 | -15,589 | -281 | 2,169,931 | ||||
| 2014-11-24 | 2014-11-21 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.0388 | -214 | -4 | 19,299 | ||||
| 2014-11-24 | 2014-11-21 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.0388 | -2,304 | -42 | 207,448 | ||||
| 2014-11-24 | 2014-11-21 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.0388 | -24,275 | -438 | 2,185,520 | ||||
| 2014-11-21 | 2014-11-20 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.3205 | -72 | -1 | 19,513 | ||||
| 2014-11-21 | 2014-11-20 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.3205 | -774 | -14 | 209,752 | ||||
| 2014-11-21 | 2014-11-20 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 18.3205 | -8,154 | -149 | 2,209,795 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.3823 | -1,531 | -30 | 19,585 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.3823 | -16,456 | -319 | 210,526 | ||||
| 2014-11-20 | 2014-11-18 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.3823 | -173,375 | -3,360 | 2,217,949 | ||||
| 2014-11-17 | 2014-11-13 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.4322 | -99 | -2 | 21,116 | ||||
| 2014-11-17 | 2014-11-13 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.4322 | -1,070 | -21 | 226,982 | ||||
| 2014-11-17 | 2014-11-13 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.4322 | -11,269 | -219 | 2,391,324 | ||||
| 2014-11-14 | 2014-11-12 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.4210 | -290 | -6 | 21,215 | ||||
| 2014-11-14 | 2014-11-12 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.4210 | -3,113 | -60 | 228,052 | ||||
| 2014-11-14 | 2014-11-12 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 19.4210 | -32,797 | -637 | 2,402,593 | ||||
| 2014-11-13 | 2014-11-11 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 19.3700 | -800,000 | -15,496 | 2,559,374 | ||||
| 2014-10-01 | 2014-09-29 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 20.0168 | -12,556 | -251 | 3,359,374 | ||||
| 2014-06-13 | 2014-06-11 | 4 | Brumm Joshua T | VSAR | Stock Option (Right to Buy) | D | 31.96 | 32,000 | 32,000 | |||||
| 2014-06-13 | 2014-06-11 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 15,000 | 25,000 | ||||||
| 2014-06-13 | 2014-06-11 | 4 | Cleland Jeffrey L | VSAR | Stock Option (Right to Buy) | D | 31.96 | 100,000 | 100,000 | |||||
| 2014-06-13 | 2014-06-11 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 30,000 | 146,280 | ||||||
| 2014-06-13 | 2014-06-11 | 4 | Westberg Paul | VSAR | Stock Option (Right to Buy) | D | 31.96 | 25,000 | 25,000 | |||||
| 2014-06-13 | 2014-06-11 | 4 | Westberg Paul | VSAR | Common Stock | D | 7,500 | 17,500 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Brumm Joshua T | VSAR | Common Stock | D | 10,000 | 10,000 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Cleland Jeffrey L | VSAR | Common Stock | D | 10,000 | 116,280 | ||||||
| 2014-04-17 | 2014-04-15 | 4 | Westberg Paul | VSAR | Common Stock | D | 10,000 | 10,000 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series B Convertible Preferred Stock | D | 0.00 | -759,565 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Warrant | D | 0.45 | -759,565 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series E Convertible Preferred Stock | D | 0.00 | -3,546,094 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series D2 Convertible Preferred Stock | D | 0.00 | -1,349,433 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series D1 Convertible Preferred Stock | D | 0.00 | -3,050,019 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series C Convertible Preferred Stock | D | 0.00 | -8,439,620 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Series B Convertible Preferred Stock | D | 0.00 | -20,942,466 | 0 | |||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 21.0200 | 60,000 | 1,261 | 3,371,930 | ||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 66,049 | 3,311,930 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 308,356 | 3,245,881 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 117,342 | 2,937,525 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 265,219 | 2,820,183 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 733,880 | 2,554,964 | ||||||
| 2014-03-28 | 2014-03-27 | 4 | New Leaf Ventures II, L.P. | VSAR | Common Stock | D | 1,821,084 | 1,821,084 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series E Convertible Preferred Stock | D | -485,664 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series D-2 Convertible Preferred Stock | D | -802,596 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series D-1 Convertible Preferred Stock | D | -775,315 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Series B Convertible Preferred Stock | D | -23,403 | 0 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 21.0000 | 60,000 | 1,260 | 2,146,978 | ||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 485,664 | 2,086,978 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 802,596 | 1,601,314 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 775,315 | 798,718 | ||||||
| 2014-03-28 | 2014-03-26 | 4 | AKKARAJU SRINIVAS | VSAR | Common Stock | D | 23,403 | 23,403 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series E Convertible Preferred Stock | I | -1,773,049 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series D-2 Convertible Preferred Stock | I | -899,619 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series D-1 Convertible Preferred Stock | I | -2,033,350 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series C Convertible Preferred Stock | I | -5,626,413 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series B Convertible Preferred Stock | I | -14,468,020 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Series B Convertible Preferred Stock | I | 506,376 | 14,468,020 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Warrants to Purchase Series B Preferred Stock | I | 0.45 | -506,376 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 21.0000 | 60,000 | 1,260 | 2,216,558 | ||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 154,178 | 2,156,558 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 78,228 | 2,002,380 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 176,813 | 1,924,152 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 489,253 | 1,747,339 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Malik Shahzad See FN | VSAR | Common Stock | I | 1,258,086 | 1,258,086 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series E Convertible Preferred Stock | I | -5,486,820 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series D-2 Convertible Preferred Stock | I | -654,796 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series D-1 Convertible Preferred Stock | I | -1,479,993 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series C Convertible Preferred Stock | I | -14,222,222 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Series B Convertible Preferred Stock | I | -403,704 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 21.0000 | 60,000 | 1,260 | 1,994,568 | ||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 477,115 | 1,934,568 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 56,939 | 1,457,453 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 128,695 | 1,400,514 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 1,236,715 | 1,271,819 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | SUN ANTHONY Y See FN | VSAR | Common Stock | I | 35,104 | 35,104 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series E Convertible Preferred Stock | I | -5,486,820 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series D-2 Convertible Preferred Stock | I | -654,796 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series D-1 Convertible Preferred Stock | I | -1,479,993 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series C Convertible Preferred Stock | I | -14,222,222 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Series B Convertible Preferred Stock | I | -403,704 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 21.0000 | 60,000 | 1,260 | 1,994,568 | ||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 477,115 | 1,934,568 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 56,939 | 1,457,453 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 128,695 | 1,400,514 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 1,236,715 | 1,271,819 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | AISLING CAPITAL III LP See FN | VSAR | Common Stock | I | 35,104 | 35,104 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5.18 | -510 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5.18 | 510 | 510 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Series B Convertible Preferred Stock | D | 0.45 | -5,872 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-2 Convertible Preferred Stock | D | -5,796 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-1 Convertible Preferred Stock | D | -13,040 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series C Convertible Preferred Stock | D | -65,250 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Seires B Convertible Preferred Stock | D | -70,792 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series A Convertible Preferred Stock | D | -88,000 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5.18 | -5,489 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5.18 | 5,489 | 5,489 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Series B Convertible Preferred Stock | D | 0.45 | -63,127 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-2 Convertible Preferred Stock | D | -62,297 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-1 Convertible Preferred Stock | D | -140,174 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series C Convertible Preferred Stock | D | -701,432 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series B Convertible Prefered Stock | D | -760,994 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series A Convertible Preferred Stock | D | -945,973 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5.18 | -57,831 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Common Stock | D | 5.18 | 57,831 | 57,831 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Warrant to Purchase Series B Convertible Preferred Stock | D | 0.45 | -665,057 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-2 Convertible Preferred Stock | D | -656,313 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series D-1 Convertible Preferred Stock | D | -1,476,754 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series C Convertible Preferred Stock | D | -7,389,507 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series B Convertible Preferred Stock | D | -8,017,215 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Series A Convertible Preferred Stock | D | -9,966,027 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 384 | 21,503 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 21,119 | 21,119 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 4,136 | 231,168 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 227,032 | 227,032 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 43,579 | 2,435,389 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Index Ventures IV (Jersey) LP | VSAR | Common Stock | D | 2,391,810 | 2,391,810 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series E Convertible Preferred Stock | I | -1,773,049 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series D-2 Convertible Preferred Stock | I | -899,619 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series D-1 Convertible Preferred Stock | I | -2,033,350 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series C Convertible Preferred Stock | I | -5,626,413 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series B Convertible Preferred Stock | I | -14,468,020 | 0 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Series B Convertible Preferred Stock | I | 506,376 | 14,468,020 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Warrants to Purchase Series B Preferred Stock | I | 0.45 | -506,376 | 0 | |||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 21.0000 | 60,000 | 1,260 | 2,216,558 | ||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 154,178 | 2,156,558 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 78,228 | 2,002,380 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 176,813 | 1,924,152 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 489,253 | 1,747,339 | ||||||
| 2014-03-27 | 2014-03-26 | 4 | Advent Life Sciences LLP See FN | VSAR | Common Stock | I | 1,258,086 | 1,258,086 | ||||||
| 2014-03-24 | 2014-03-20 | 4 | AKKARAJU SRINIVAS | VSAR | Stock Option (Right to Buy) | D | 21.00 | 35,000 | 35,000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | Malik Shahzad | VSAR | Stock Option (Right to Buy) | D | 21.00 | 35,000 | 35,000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | JENNINGS EDMON R | VSAR | Stock Option (Right to Buy) | D | 21.00 | 35,000 | 35,000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | SUN ANTHONY Y | VSAR | Stock Option (Right to Buy) | D | 21.00 | 35,000 | 35,000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | Varian John | VSAR | Stock Option (Right to Buy) | D | 21.00 | 35,000 | 35,000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | Dybbs Michael | VSAR | Stock Option (Right to Buy) | D | 21.00 | 35,000 | 35,000 | |||||
| 2014-03-24 | 2014-03-20 | 4 | De Rubertis Francesco | VSAR | Stock Option (Right to Buy) | D | 21.00 | 35,000 | 35,000 | |||||
| 2014-03-20 | 3 | Varian John | VSAR | Common Stock | D | 0 | ||||||||
| 2014-03-20 | 3 | De Rubertis Francesco | VSAR | Common Stock | D | 0 | ||||||||
| 2014-03-20 | 3 | Cleland Jeffrey L | VSAR | Common Stock | D | 212,560 | ||||||||
| 2014-03-20 | 3 | Cleland Jeffrey L | VSAR | Common Stock | D | 212,560 |
P
공개 시장에서 또는 사적으로 비파생증권 또는 파생증권 매입
S
공개 시장에서 또는 사적으로 비파생증권 또는 파생증권 매각
A
자사로부터 유가증권(옵션 등)을 보조, 지급 또는 기타 취득
C
파생상품 전환
D
자사에게 유가증권을 매각 또는 양도
F
기업으로부터 인도 받은 유가증권의 일부를 사용한 행사 가격 또는 조세 채무의 지급
G
내부자에 의한 또는 내부자에게 증권 증여
K
지분스왑 및 유사 위험 회피거래
M
자사로부터 인도 받은 파생증권(옵션 등)의 행사 또는 전환
V
보고서 양식 4에 자진 신고된 거래
J
기타 (거래 내용을 설명하는 각주와 동반)
