| 내부자 지분 | 10,007,540 shares |
내부자 센티멘트 점수
내부자 센티멘트 점수를 통해서 내부자들이 법인 지분을 매입하는 기업들에 대해서 알아볼 수 있습니다.
이는 내부자의 누적도가 가장 높은 기업을 식별하는 정교하고 복합적인 지수를 분석하는 계량 모델의 결과 값입니다. 스코어링 모델은 이전 90일 동안 매수한 "내부자의 순 숫자", "매수한 주식의 총합", "내부자가 소유한 주식의 총합"의 조합을 사용합니다. 점수는 0에서 100 사이이며, 점수가 높을수록 피어(Peer: 동종업계 경쟁기업)에 대한 누적도가 높다는 것을 나타내며, 평균은 50입니다.
업데이트 주기: 일별
내부자의 누적도가 가장 높은 기업 목록을 확인할 수 있는 내부자들의 최다 선택(Insiders Top Picks)을 참고하십시오.
내부 경영진 센티멘트 점수
내부 경영진 센티멘트 점수를 통해서 내부 경영진들이 법인 지분을 매입하는 기업들에 대해서 알아볼 수 있습니다.
내부 거래의 정의에 따라 내부 경영진(기업 임원)도 내부자이지만, 다른 내부자(10% 주주 및 이사회 구성원)들과는 달리 내부 경영진은 매일 회사에서 근무하며, 거래 시에 자신의 자금을 사용합니다. (많은 경우에 10% 주주 및 이사회 구성원은 다른 사람의 자금을 관리하는 자금 관리자입니다.) 따라서 내부 경영진(기업 임원: Officer)의 내부 거래는 훨씬 더 중요하며 올바른 분석이 필요합니다.
내부자 센티멘트 점수와 마찬가지로 임원 감정 점수는 가장 높은 수준의 임원 축적을 가진 기업을 식별하는 정교하고 복합적인 지수 퀀트(Multi-factor quantitative) 모델의 결과입니다.
업데이트 주기: 일별
내부자의 누적도가 가장 높은 기업 목록을 확인할 수 있는 내부자들의 최다 선택(Insiders Top Picks)을 참고하십시오.
주요 내부자 지표
이 수치는 해당 기업이 다양한 내부자 지표에 따라 어떻게 순위를 매겨지는 지를 설명합니다. 백분위 순위는 이 기업이 미국 시장의 다른 기업들과 어떻게 비교되는지 보여줍니다. 순위가 높을수록 더 나은 상황에 있다는 것을 의미합니다.
예를 들어, 일반적으로 내부자의 매입은 긍정적인 지표라고 간주되어지기 때문에, 내부자의 매입(내부자의 매각, 역시도)가 적은 기업보다 내부자의 매입이 많은 기업은 순위가 높을 것입니다.
내부자의 순 매입(순위)
N/A
내부자의 순 매입(Net Number of Insiders Buying)는 내부자 매수의 총 수에서 지난 90일 동안의 내부자 매도의 총 수를 뺀 값입니다. 여기에 백분위 순위가 표시됩니다(범위: 0~100%).
내부자가 매입한 플로트 비율 (순위)
N/A
"내부자가 매입한 플로트 비율(Percent of Float Bought by Insiders)"은 내부자가 매입한 주식의 총 수에서 내부자가 매도한 주식의 총 수를 뺀 값을 전체 플로트로 나눈 값에 100을 곱한 값입니다. * ((내부자가 매입한 주식의 총 수 - 내부자가 매도한 주식의 총 수) ÷ 전체 플로트) x 100
내부자 트레이딩 차트
Alpine Immune Sciences, Inc. 내부자의 매매 거래는 아래 차트에 나와 있습니다. 내부자들은 기업의 임원(내부 경영진), 이사 또는 주요 투자자입니다. 일반적으로 내부자가 중요한 비공개 정보를 기반으로 자신이 속한 기업을 거래하는 것은 불법으로 간주됩니다. 이것은 내부자가 자신의 기업 내에서 행하는 모든 거래가 불법이라는 것을 뜻은 아닙니다. 그러나 그들은 자신들의 모든 거래를 양식 4를 통해 SEC에 보고해야만 합니다.
내부자의 명단 및 이익 지표
아래 표는 공개된 내부자의 목록이며, SEC에 공개된 제출 문서에서 자동으로 생성됩니다. "이름", "가장 최근의 직급", "이사, 임원 또는 10% 주주"에 대한 지정 외에도 최근에 공개된 보유 주식에 대한 정보를 보여줍니다. 또한 가능한 경우 내부자의 과거 거래 실적도 확인 가능합니다. 과거 거래 실적은 내부자가 실제 "공개 시장"(Open market) 매입 거래를 수행한 실적을 가중 평균한 값입니다. 이 계산 방법에 대한 자세한 내용은 유튜브 웨비나 를 참조하시면 됩니다.
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| 내부자 | 평균 이익률 (%) | 소유 지분 |
주식 분할 |
|---|
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내부자의 매입 내역 추적: 단기 이익 분석
이 섹션에서는 ALPN / Alpine Immune Sciences, Inc.에서 계획되지 않은 "공개 시장"(Open market)의 내부자가 매입한 모든 상품의 수익성을 분석합니다. 이 분석을 통해서 내부자가 비정상적인 수익을 지속적으로 창출하는지 파악하는 데 도움이 되며, 이러한 분석은 수행해볼 가치가 있습니다. 이 분석은 개별 거래 후 1년 동안 수행한 것이며, 결과는 이론 값입니다. .
아래 표는 사전 거래 계획(Automated trading plan)에 포함되지 않은 가장 최근의 "공개 시장"(Open market)에서의 매입을 보여줍니다.
조정된 가격은 분할 조정 가격입니다. 조정된 지분은 분할 조정 지분입니다.
내부자 매매의 실적: 단기 손실 분석
이 섹선에서는 ALPN / Alpine Immune Sciences, Inc.에서 이루어진 "공개 시장(Open market)"에서의 모든 계획되지 않은 내부자 매매의 단기 손실 회피(Short-term loss avoidance)를 분석합니다. 일관된 손실 회피 패턴을 통해서 향후 매매 거래가 가격 하락을 초래할 수도 있음을 예상할 수 있습니다. 이 분석은 각 각 매매 거래 후 1년 동안의 자료이며, 결과는 이론 값입니다. .
아래 표는 사전 거래 계획(Automated trading plan)에 포함되지 않은 가장 최근의 공개 시장에서의 매매를 보여줍니다.
조정된 가격은 분할 조정 가격입니다. 조정된 지분은 분할 조정 지분입니다.
거래 내역
전체 거래 내역을 보려면 링크 아이콘을 클릭하세요. 10b5-1 자동 거래 계획의 일부로 보고된 거래는 10b-5 열에 X 표시가 나타납니다.
| 보고일 | 거래일 | 양식 | 내부자 | 티커 | 증권 소유권 | 코드 | 직접 | 행사 가격 |
단위 가격 |
단위 변동 |
가치 변동 (단위: 1,000) |
잔여 옵션 |
잔여 주식 |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-05-20 | 2024-05-20 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | -1,900 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | -50,000 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | -2,829,347 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | -264,315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | -2,416,181 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | -1,735,544 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | -6,582,380 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | -31,200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | Rickey James Paul | ALPN | Common Stock | D | -26,761 | 31,200 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | -48,000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | PENG STANFORD L | ALPN | Common Stock | D | -296,163 | 48,000 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -96,000 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -13,245 | 96,000 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -2,627,157 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | -7,300 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | -22,820 | 7,300 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | -31,200 | 0 | ||||||
| 2024-05-20 | 2024-05-20 | 4 | DURAND REMY | ALPN | Common Stock | D | -102,192 | 31,200 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | -264,315 | 0 | ||||||
| 2024-05-20 | 2024-05-18 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | -2,416,181 | 0 | ||||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6.3300 | 13,377 | 85 | 344,163 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 3.2300 | 26,912 | 87 | 330,786 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 11.3100 | 22,593 | 256 | 303,874 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0.6500 | 161,492 | 105 | 281,281 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 0.6500 | 37,267 | 24 | 119,789 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 6.5100 | 3,126 | 20 | 82,522 | ||||
| 2024-05-10 | 2024-05-08 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 13.2000 | 7,025 | 93 | 79,396 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4.7600 | 10,000 | 48 | 133,392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 3.2300 | 38,078 | 123 | 123,392 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 4.0900 | 12,365 | 51 | 85,314 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 6.5100 | 25,000 | 163 | 72,949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | DURAND REMY | ALPN | Common Stock | D | 13.2000 | 9,845 | 130 | 47,949 | ||||
| 2024-05-10 | 2024-05-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 7.5500 | 13,245 | 100 | 109,245 | ||||
| 2024-05-10 | 2024-05-08 | 4 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 12.0700 | 22,820 | 275 | 30,120 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5.0200 | 398 | 2 | 57,961 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3.2300 | 18,286 | 59 | 57,563 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11.3100 | 164 | 2 | 39,277 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6.5100 | 857 | 6 | 39,113 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13.2000 | 7,055 | 93 | 38,256 | ||||
| 2024-05-09 | 2024-05-07 | 4 | Rickey James Paul | ALPN | Common Stock | D | 7.5500 | 1 | 0 | 31,201 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 64.5700 | -19 | -1 | 2,829,347 | ||||
| 2024-04-29 | 2024-04-25 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 0.0010 | 1,200,000 | 1 | 2,829,366 | ||||
| 2024-04-05 | 3 | FUHS ULRICH MARTIN | ALPN | Common Stock | D | 7,300 | ||||||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 25.0000 | -44,000 | -1,100 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 11.3100 | 44,000 | 498 | 44,000 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22.3121 | -73,764 | -1,646 | 0 | ||||
| 2024-01-29 | 2024-01-26 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6.5100 | 73,764 | 480 | 73,764 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 22.0000 | -236 | -5 | 0 | ||||
| 2024-01-29 | 2024-01-25 | 4 | Rickey James Paul | ALPN | Common Stock | D | 6.5100 | 236 | 2 | 236 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 12.7400 | 1,234,636 | 15,729 | 6,582,380 | ||||
| 2024-01-22 | 2024-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12.7400 | 1,234,636 | 15,729 | 6,582,380 | ||||
| 2024-01-16 | 2024-01-11 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 12.7400 | 145,251 | 1,850 | 2,416,181 | ||||
| 2024-01-16 | 2024-01-11 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 12.7400 | 145,251 | 1,850 | 2,416,181 | ||||
| 2024-01-05 | 2024-01-04 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 48,000 | 72,371 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 96,000 | 96,000 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 31,200 | 31,200 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | DURAND REMY | ALPN | Common Stock | D | 31,200 | 38,104 | ||||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 19.6500 | -48,264 | -948 | 2,627,157 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 12.7400 | 74,441 | 948 | 2,675,421 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20.0413 | -1,016 | -20 | 0 | ||||
| 2023-12-29 | 2023-12-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0.6500 | 1,016 | 1 | 1,016 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18.3200 | -139,166 | -2,550 | 264,315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 18.3200 | -1,195,683 | -21,905 | 2,270,930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19.8200 | -3,128 | -62 | 403,481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19.8200 | -26,872 | -533 | 3,466,613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19.9600 | -18,922 | -378 | 406,609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | Thompson Peter A. See footnotes | ALPN | Common Stock | I | 19.9600 | -162,576 | -3,245 | 3,493,485 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18.3200 | -139,166 | -2,550 | 264,315 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 18.3200 | -1,195,683 | -21,905 | 2,270,930 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19.8200 | -3,128 | -62 | 403,481 | ||||
| 2023-12-29 | 2023-12-28 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19.8200 | -26,872 | -533 | 3,466,613 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19.9600 | -18,922 | -378 | 406,609 | ||||
| 2023-12-29 | 2023-12-27 | 4 | ORBIMED ADVISORS LLC See footnotes | ALPN | Common Stock | I | 19.9600 | -162,576 | -3,245 | 3,493,485 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20.0425 | -29,573 | -593 | 0 | ||||
| 2023-12-27 | 2023-12-27 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0.6500 | 29,573 | 19 | 29,573 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20.2245 | -24,486 | -495 | 0 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0.6500 | 22,084 | 14 | 24,486 | ||||
| 2023-12-27 | 2023-12-26 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0.4500 | 2,402 | 1 | 2,402 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20.4255 | -37,825 | -773 | 0 | ||||
| 2023-12-27 | 2023-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0.4500 | 37,825 | 17 | 37,825 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19.2087 | -15,213 | -292 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5.0200 | 15,213 | 76 | 15,213 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 20.0099 | -2,402 | -48 | 0 | ||||
| 2023-12-21 | 2023-12-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0.4500 | 2,402 | 1 | 2,402 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19.0017 | -1,800 | -34 | 0 | ||||
| 2023-12-18 | 2023-12-18 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5.0200 | 1,800 | 9 | 1,800 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19.0888 | -45,387 | -866 | 0 | ||||
| 2023-12-18 | 2023-12-15 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5.0200 | 45,387 | 228 | 45,387 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 19.0005 | -11,600 | -220 | 0 | ||||
| 2023-12-18 | 2023-12-14 | 4 | Rickey James Paul | ALPN | Common Stock | D | 5.0200 | 11,600 | 58 | 11,600 | ||||
| 2023-12-13 | 2023-12-11 | 4 | Topper James N By: Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 12.7400 | 145,251 | 1,850 | 1,629,366 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17.3155 | -8,613 | -149 | 0 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 0.4500 | 8,613 | 4 | 8,613 | ||||
| 2023-12-12 | 2023-12-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17.3155 | -32,450 | -562 | 0 | ||||
| 2023-12-12 | 2023-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17.2648 | -68,870 | -1,189 | 32,450 | ||||
| 2023-12-12 | 2023-12-08 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 17.0799 | -8,067 | -138 | 101,320 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16.0797 | -6,446 | -104 | 0 | ||||
| 2023-12-06 | 2023-12-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3.2300 | 6,446 | 21 | 6,446 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16.0139 | -418 | -7 | 0 | ||||
| 2023-12-06 | 2023-12-05 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3.2300 | 418 | 1 | 418 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16.0584 | -63,947 | -1,027 | 0 | ||||
| 2023-12-06 | 2023-12-04 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3.2300 | 63,947 | 207 | 63,947 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16.0000 | -700 | -11 | 0 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3.2300 | 700 | 2 | 700 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 12.5000 | 375,000 | 4,688 | 1,735,544 | ||||
| 2023-11-14 | 2023-11-09 | 4 | Decheng Capital Global Healthcare Fund (Master), LP | ALPN | Common Stock | D | 12.5000 | 375,000 | 4,688 | 1,735,544 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 16.0281 | -18,003 | -289 | 0 | ||||
| 2023-11-08 | 2023-11-06 | 4 | Rickey James Paul | ALPN | Common Stock | D | 3.2300 | 10,989 | 35 | 18,003 | ||||
| 2023-04-27 | 3 | DURAND REMY | ALPN | Common Stock | D | 6,904 | ||||||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7.3500 | 1,360,544 | 10,000 | 1,360,544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 7.3500 | 639,456 | 4,700 | 5,347,744 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | I | 7.3500 | 1,360,544 | 10,000 | 1,360,544 | ||||
| 2022-09-27 | 2022-09-23 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 7.3500 | 639,456 | 4,700 | 5,347,744 | ||||
| 2022-07-19 | 2022-07-15 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 0.4500 | 20,063 | 9 | 238,126 | ||||
| 2022-02-15 | 2022-02-11 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 7.1006 | 112,665 | 800 | 1,484,115 | ||||
| 2022-01-06 | 2022-01-04 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13.30 | 215,000 | 215,000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13.30 | 215,000 | 215,000 | |||||
| 2022-01-06 | 2022-01-04 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13.30 | 112,500 | 112,500 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13.89 | 10,000 | 10,000 | |||||
| 2022-01-04 | 2021-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 13.9162 | -17,013 | -237 | 7,014 | ||||
| 2022-01-04 | 2022-01-03 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13.89 | 10,000 | 10,000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13.89 | 10,000 | 10,000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13.89 | 10,000 | 10,000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13.89 | 10,000 | 10,000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13.89 | 10,000 | 10,000 | |||||
| 2022-01-04 | 2022-01-03 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13.89 | 10,000 | 10,000 | |||||
| 2021-09-27 | 2021-09-23 | 4/A | Peetz Christopher Christopher Peetz and Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10.1700 | 1,900 | 19 | 1,900 | ||||
| 2021-09-27 | 2021-09-23 | 4/A | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10.0769 | 15,000 | 151 | 50,000 | ||||
| 2021-09-24 | 2021-09-23 | 4 | Peetz Christopher Christopher Peetz & Christine Peetz TR UA 02/15/2017 The Peetz Living Trust | ALPN | Common Stock | I | 10.1700 | 1,900 | 19 | 1,900 | ||||
| 2021-09-24 | 2021-09-23 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 10.0769 | 15,000 | 151 | 50,000 | ||||
| 2021-09-23 | 2021-09-21 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 9.7966 | 10,000 | 98 | 35,000 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9.4000 | 425,531 | 4,000 | 425,531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 9.4000 | 585,106 | 5,500 | 3,656,061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Decheng Capital China Life Sciences USD Fund III, L.P. | ALPN | Common Stock | D | 9.4000 | 1,542,553 | 14,500 | 4,708,288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9.4000 | 425,531 | 4,000 | 425,531 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 9.4000 | 585,106 | 5,500 | 3,656,061 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 9.4000 | -400,000 | -3,760 | 2,600,980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10.0076 | -45,262 | -453 | 109,387 | ||||
| 2021-09-21 | 2021-09-17 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9.4000 | -400,000 | -3,760 | 2,600,980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 9.4000 | -400,000 | -3,760 | 2,600,980 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 9.4000 | 1,542,553 | 14,500 | 4,708,288 | ||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 0.00 | 1,200,000 | 1,200,000 | |||||
| 2021-09-21 | 2021-09-17 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | -1,200,000 | 1,371,450 | ||||||
| 2021-09-17 | 2021-09-16 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10.0024 | -6,768 | -68 | 154,649 | ||||
| 2021-09-17 | 2021-09-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10.0000 | -3,484 | -35 | 161,417 | ||||
| 2021-06-29 | 2021-06-28 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10.0005 | -3,479 | -35 | 164,901 | ||||
| 2021-06-29 | 2021-06-25 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10.0143 | -9,473 | -95 | 168,380 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Goldberg Zelanna | ALPN | Stock Option (Right to buy) | D | 10.29 | 160,000 | 160,000 | |||||
| 2021-05-21 | 2021-05-20 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15.0006 | -1,221 | -18 | 177,853 | ||||
| 2021-05-21 | 2021-05-19 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 15.0283 | -50,965 | -766 | 179,074 | ||||
| 2021-05-14 | 2021-05-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11.5169 | -10,000 | -115 | 230,039 | ||||
| 2021-05-14 | 2021-05-12 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11.6842 | -10,000 | -117 | 240,039 | ||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3.62 | -7,650 | 0 | |||||
| 2021-04-23 | 2021-03-31 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 3.6233 | 7,650 | 28 | 218,063 | ||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4.09 | -7,650 | 0 | |||||
| 2021-04-23 | 2021-03-30 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 4.0900 | 7,650 | 31 | 210,413 | ||||
| 2021-04-15 | 2021-04-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10.5200 | -10,000 | -105 | 250,039 | ||||
| 2021-04-15 | 2021-04-13 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 10.0714 | -10,000 | -101 | 260,039 | ||||
| 2021-03-08 | 2021-03-05 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12.9875 | -10,000 | -130 | 270,039 | ||||
| 2021-03-08 | 2021-03-04 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13.0108 | -10,000 | -130 | 280,039 | ||||
| 2021-02-03 | 2021-02-02 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 11.7381 | -10,000 | -117 | 290,039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 13.2029 | -7,021 | -93 | 300,039 | ||||
| 2021-02-03 | 2021-02-01 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12.0738 | -2,979 | -36 | 307,060 | ||||
| 2021-01-06 | 2021-01-05 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 13.20 | 150,000 | 150,000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 13.20 | 255,000 | 255,000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 13.20 | 120,000 | 120,000 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Hernday Natasha | ALPN | Stock Option (Right to buy) | D | 13.45 | 7,650 | 7,650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 13.45 | 7,650 | 7,650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 13.45 | 7,650 | 7,650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 13.45 | 7,650 | 7,650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 13.45 | 7,650 | 7,650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 13.45 | 7,650 | 7,650 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 13.45 | 7,650 | 7,650 | |||||
| 2021-01-04 | 2020-12-31 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 12.6000 | -3,923 | -49 | 24,371 | ||||
| 2021-01-04 | 2020-12-31 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 12.6000 | -11,123 | -140 | 310,039 | ||||
| 2021-01-04 | 2020-12-31 | 4 | Rickey James Paul | ALPN | Common Stock | D | 12.6000 | -2,258 | -28 | 24,027 | ||||
| 2020-12-30 | 2020-12-28 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 14.2500 | -600,000 | -8,550 | 3,070,955 | ||||
| 2020-12-30 | 2020-12-28 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 14.2500 | -600,000 | -8,550 | 3,070,955 | ||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 260,528 | 321,162 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | GOLD MITCHELL By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -993,801 | 3,000,980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 181,024 | 202,763 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Venkatesan Jay By Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | -993,801 | 3,000,980 | ||||||
| 2020-12-22 | 2020-12-22 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | -993,801 | 3,000,980 | ||||||
| 2020-12-11 | 2020-12-10 | 4 | Hernday Natasha | ALPN | Stock Option (right to buy) | D | 11.07 | 15,000 | 15,000 | |||||
| 2020-11-23 | 2020-11-19 | 4 | CONWAY ROBERT E By Robert E. Conway Rev Trust and Carolyn J. Conway Rev Trust | ALPN | Common Stock | I | 8.0300 | 10,000 | 80 | 25,000 | ||||
| 2020-07-09 | 2020-07-08 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 7.20 | 50,000 | 50,000 | |||||
| 2020-07-01 | 2020-06-30 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 9.7100 | -3,923 | -38 | 28,294 | ||||
| 2020-07-01 | 2020-06-30 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 9.7100 | -8,227 | -80 | 60,634 | ||||
| 2020-07-01 | 2020-06-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 9.7100 | -2,258 | -22 | 26,285 | ||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 3.23 | 270,000 | 270,000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 67,569 | 68,861 | ||||||
| 2020-01-27 | 2019-12-23 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -5,000 | 1,292 | ||||||
| 2020-01-27 | 2019-12-11 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -5,000 | 6,292 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 3.23 | 108,000 | 108,000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | PENG STANFORD L | ALPN | Common Stock | D | 32,217 | 32,217 | ||||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 3.23 | 102,000 | 102,000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | Rickey James Paul | ALPN | Common Stock | D | 18,543 | 28,543 | ||||||
| 2020-01-06 | 2020-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 3.62 | 7,650 | 7,650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 3.62 | 7,650 | 7,650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Cui Xiangmin | ALPN | Stock Option (Right to buy) | D | 3.62 | 7,650 | 7,650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 3.62 | 7,650 | 7,650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 3.62 | 7,650 | 7,650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 3.62 | 7,650 | 7,650 | |||||
| 2020-01-06 | 2020-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 3.62 | 7,650 | 7,650 | |||||
| 2019-06-03 | 2019-05-30 | 4 | Rickey James Paul | ALPN | Common Stock | D | 4.9500 | 10,000 | 50 | 10,000 | ||||
| 2019-02-12 | 2019-02-08 | 4 | TIGER MANAGEMENT L.L.C. | ALPN | Common Stock | I | 5.8498 | -25,000 | -146 | 137,728 | ||||
| 2019-02-08 | 2019-02-06 | 4 | PENG STANFORD L | ALPN | Stock Option (right to buy) | D | 6.51 | 75,000 | 75,000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6.51 | 75,000 | 75,000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6.81 | 25,000 | 25,000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | GOLD MITCHELL | ALPN | Stock Option (right to buy) | D | 6.51 | 200,000 | 200,000 | |||||
| 2019-02-08 | 2019-02-06 | 4 | Rickey James Paul | ALPN | Stock Option (right to buy) | D | 6.51 | 75,000 | 75,000 | |||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6,331,470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6,331,470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6,331,470 | ||||||||
| 2019-01-23 | 3 | Decheng Capital Management III (Cayman), LLC | ALPN | Common Stock | I | 6,331,470 | ||||||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Stock Option (right to buy) | D | 5.70 | 7,650 | 7,650 | |||||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Warrant (right to buy) | I | 12.74 | 5.3700 | 1,234,636 | 6,630 | 1,234,636 | |||
| 2019-01-23 | 2019-01-18 | 4 | Cui Xiangmin | ALPN | Common Stock | I | 5.3700 | 3,165,735 | 17,000 | 3,165,735 | ||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145,251 | 145,251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 5.3700 | 372,439 | 2,000 | 3,670,955 | ||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Warrants to Purchase Common Stock | I | 145,251 | 145,251 | ||||||
| 2019-01-23 | 2019-01-18 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 5.3700 | 372,439 | 2,000 | 3,670,955 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12.74 | 74,441 | 74,441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Venkatesan Jay Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5.3700 | 190,875 | 1,025 | 3,994,781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | I | 12.74 | 74,441 | 74,441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | GOLD MITCHELL Alpine ImmunoSciences, L.P. | ALPN | Common Stock | I | 5.3700 | 190,875 | 1,025 | 3,994,781 | ||||
| 2019-01-22 | 2018-05-21 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -6,000 | 11,292 | ||||||
| 2019-01-22 | 2018-05-15 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -3,000 | 17,292 | ||||||
| 2019-01-22 | 2018-05-14 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | -3,000 | 20,292 | ||||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Warrant (right to buy) | D | 12.74 | 74,441 | 74,441 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 5.3700 | 190,875 | 1,025 | 3,994,781 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | I | 12.74 | 145,251 | 145,251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Topper James N By Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | I | 5.3700 | 372,439 | 2,000 | 2,571,450 | ||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Warrant (Right to Buy) | D | 12.74 | 145,251 | 145,251 | |||||
| 2019-01-22 | 2019-01-18 | 4 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 5.3700 | 372,439 | 2,000 | 2,571,450 | ||||
| 2019-01-04 | 2019-01-02 | 4 | Peetz Christopher | ALPN | Stock Option (Right to buy) | D | 4.09 | 7,650 | 7,650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 4.09 | 7,650 | 7,650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 4.09 | 7,650 | 7,650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 4.09 | 7,650 | 7,650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 4.09 | 7,650 | 7,650 | |||||
| 2019-01-04 | 2019-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 4.09 | 7,650 | 7,650 | |||||
| 2018-10-02 | 2018-09-28 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 6.33 | 250,000 | 250,000 | |||||
| 2018-08-08 | 2018-08-06 | 4 | Litton Mark James | ALPN | Stock Option (right to buy) | D | 6.81 | 150,000 | 150,000 | |||||
| 2018-04-24 | 2018-04-20 | 4 | Peetz Christopher | ALPN | Stock Option (right to buy) | D | 7.91 | 7,650 | 7,650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | GOLD MITCHELL | ALPN | Stock Option (Right to buy) | D | 11.31 | 70,000 | 70,000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Rickey James Paul | ALPN | Stock Option (Right to buy) | D | 11.31 | 45,000 | 45,000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | SEKHRI PAUL J | ALPN | Stock Option (Right to buy) | D | 11.31 | 7,650 | 7,650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Topper James N | ALPN | Stock Option (Right to buy) | D | 11.31 | 7,650 | 7,650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Thompson Peter A. | ALPN | Stock Option (Right to buy) | D | 11.31 | 7,650 | 7,650 | |||||
| 2018-01-04 | 2018-01-02 | 4 | PENG STANFORD L | ALPN | Stock Option (Right to buy) | D | 11.31 | 65,000 | 65,000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | Venkatesan Jay | ALPN | Stock Option (Right to buy) | D | 11.31 | 25,000 | 25,000 | |||||
| 2018-01-04 | 2018-01-02 | 4 | CONWAY ROBERT E | ALPN | Stock Option (Right to buy) | D | 11.31 | 7,650 | 7,650 | |||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4,398,022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4,398,022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4,398,022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4,398,022 | ||||||||
| 2017-07-28 | 3 | Frazier Life Sciences VIII, L.P. | ALPN | Common Stock | D | 4,398,022 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7,607,812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7,607,812 | ||||||||
| 2017-07-26 | 3 | Alpine ImmunoSciences, L.P. | ALPN | Common Stock | D | 7,607,812 | ||||||||
| 2017-07-26 | 2017-07-24 | 4 | Thompson Peter A. See Footnotes | ALPN | Common Stock | I | 3,298,516 | 3,298,516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 5.02 | 208,916 | 208,916 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0.65 | 300,624 | 300,624 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Employee Stock Option (right to buy) | D | 0.45 | 51,242 | 51,242 | |||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3,803,906 | 3,803,906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL | ALPN | Common Stock | D | 23,292 | 23,292 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Aidan J. Gold | ALPN | Common Stock | I | 24,845 | 24,845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Simon P. Gold | ALPN | Common Stock | I | 24,845 | 24,845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | GOLD MITCHELL By The Mitch & Dawn Gold Irrevocable Trust fbo Noah M. Gold | ALPN | Common Stock | I | 24,845 | 24,845 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Employee Stock Option (right to buy) | D | 0.45 | 90,063 | 90,063 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay Alpine Immunosciences, L.P. | ALPN | Common Stock | I | 3,803,906 | 3,803,906 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay | ALPN | Common Stock | D | 21,739 | 21,739 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Nathaniel Graham Venkatesan | ALPN | Common Stock | I | 18,633 | 18,633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Venkatesan Jay By Raj Venkatesan as UTMA custodian for Reid Coleman Venkatesan | ALPN | Common Stock | I | 18,633 | 18,633 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | Rickey James Paul | ALPN | Employee Stock Option (right to buy) | D | 5.02 | 74,535 | 74,535 | |||||
| 2017-07-26 | 2017-07-24 | 4 | Topper James N See Footnotes | ALPN | Common Stock | I | 2,199,011 | 2,199,011 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | ORBIMED ADVISORS LLC See Footnotes | ALPN | Common Stock | I | 3,298,516 | 3,298,516 | ||||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0.65 | 37,267 | 37,267 | |||||
| 2017-07-26 | 2017-07-24 | 4 | PENG STANFORD L | ALPN | Employee Stock Option (right to buy) | D | 0.65 | 161,492 | 161,492 | |||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2500 | 1,715 | 4 | 201,811 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2500 | 6,359 | 14 | 717,089 | ||||
| 2017-06-22 | 2017-06-20 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2500 | 9,732 | 22 | 1,109,258 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2813 | 3,673 | 8 | 200,096 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2813 | 13,046 | 30 | 710,730 | ||||
| 2017-06-07 | 2017-06-07 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2813 | 20,181 | 46 | 1,099,526 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2906 | 3,920 | 9 | 196,423 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2906 | 12,624 | 29 | 697,684 | ||||
| 2017-06-07 | 2017-06-05 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2906 | 19,206 | 44 | 1,079,345 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2470 | 2,727 | 6 | 192,503 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2470 | 10,023 | 23 | 685,060 | ||||
| 2017-06-01 | 2017-05-31 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2470 | 15,350 | 34 | 1,060,139 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2957 | 1,805 | 4 | 189,776 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2957 | 6,903 | 16 | 675,037 | ||||
| 2017-06-01 | 2017-05-30 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2957 | 10,192 | 23 | 1,044,789 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3000 | 1,124 | 3 | 187,971 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3000 | 4,223 | 10 | 668,134 | ||||
| 2017-05-19 | 2017-05-19 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3000 | 6,253 | 14 | 1,034,597 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2998 | 2,909 | 7 | 186,847 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2998 | 10,541 | 24 | 663,911 | ||||
| 2017-05-19 | 2017-05-18 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2998 | 16,436 | 38 | 1,028,344 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2987 | 5,510 | 13 | 183,938 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2987 | 6,897 | 16 | 653,370 | ||||
| 2017-05-19 | 2017-05-17 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2987 | 24,965 | 57 | 1,011,908 | ||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,630,471 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 2,310,352 | ||||||||
| 2017-05-11 | 3 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value per share | D | 1,870,417 | ||||||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3429 | 675 | 2 | 178,428 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3429 | 2,565 | 6 | 646,473 | ||||
| 2017-05-11 | 2017-05-11 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3429 | 3,794 | 9 | 986,943 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3457 | 6,217 | 15 | 177,753 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3457 | 22,092 | 52 | 643,908 | ||||
| 2017-05-11 | 2017-05-10 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.3457 | 33,691 | 79 | 983,149 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2879 | 3,929 | 9 | 171,536 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2879 | 14,274 | 33 | 621,816 | ||||
| 2017-05-11 | 2017-05-09 | 4 | BVF PARTNERS L P/IL | NVLS | Common Stock, $0.001 par value | D | 2.2879 | 21,797 | 50 | 949,458 | ||||
| 2017-05-11 | 2017-05-08 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2.2800 | 15,000 | 34 | 60,000 | ||||
| 2017-05-10 | 2017-05-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2.3400 | 5,000 | 12 | 45,000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | TROHA JANICE | NVLS | Common Stock | D | 2.3400 | 10,000 | 23 | 10,000 | ||||
| 2017-05-09 | 2017-05-05 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2.3000 | 20,000 | 46 | 40,000 | ||||
| 2017-05-08 | 2017-05-04 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 2.2600 | 10,000 | 23 | 20,000 | ||||
| 2017-01-23 | 2017-01-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 2.21 | 200,000 | 200,000 | |||||
| 2017-01-23 | 2017-01-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 2.21 | 200,000 | 200,000 | |||||
| 2017-01-05 | 2017-01-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 2.2700 | -6,687 | -15 | 11,368 | ||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0.00 | -18,056 | 162,501 | |||||
| 2017-01-05 | 2017-01-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18,055 | 18,055 | ||||||
| 2016-12-05 | 2016-12-02 | 4 | Carruthers R Michael | NVLS | Common Stock | D | 2.0940 | 24,000 | 50 | 24,000 | ||||
| 2016-10-05 | 2016-10-04 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 7.9600 | -5,820 | -46 | 12,236 | ||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0.00 | -18,056 | 180,556 | |||||
| 2016-10-05 | 2016-10-03 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18,056 | 18,056 | ||||||
| 2016-09-14 | 2016-09-12 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 7.77 | 12,300 | 12,300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 7.77 | 12,300 | 12,300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 7.77 | 12,300 | 12,300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 7.77 | 12,300 | 12,300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 7.77 | 110,000 | 110,000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | SEKHRI PAUL J | NVLS | Stock Option (Right to Buy) | D | 7.77 | 12,300 | 12,300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Flynn James E Through Deerfield Management Company, L.P. | NVLS | Stock Option (right to buy) | I | 7.77 | 12,300 | 12,300 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 7.77 | 110,000 | 110,000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 7.77 | 250,000 | 250,000 | |||||
| 2016-09-14 | 2016-09-12 | 4 | Rodman David Malcom | NVLS | Stock Option (Right to Buy) | D | 7.77 | 100,000 | 100,000 | |||||
| 2016-07-06 | 2016-07-05 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 4.6600 | -5,950 | -28 | 12,105 | ||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Restricted Stock Units | D | 0.00 | -18,055 | 198,612 | |||||
| 2016-07-06 | 2016-07-01 | 4 | Rodman David Malcom | NVLS | Common Stock | D | 18,055 | 18,055 | ||||||
| 2016-06-17 | 2016-06-16 | 4 | Congleton Jon | NVLS | Common Stock | D | 3.8689 | 5,000 | 19 | 20,000 | ||||
| 2016-03-25 | 2016-03-24 | 4 | Congleton Jon | NVLS | Common Stock | D | 4.2169 | 5,000 | 21 | 15,000 | ||||
| 2016-03-23 | 2016-03-22 | 4 | Congleton Jon | NVLS | Common Stock | D | 4.3815 | 5,000 | 22 | 10,000 | ||||
| 2015-12-14 | 2015-12-11 | 4 | Congleton Jon | NVLS | Common Stock | D | 8.1000 | 5,000 | 40 | 5,000 | ||||
| 2015-12-11 | 2015-12-09 | 4 | CONWAY ROBERT E | NVLS | Common Stock | D | 8.1000 | 10,000 | 81 | 10,000 | ||||
| 2015-09-15 | 2015-09-11 | 4 | Shoemaker Steven | NVLS | Stock Option (Right to Buy) | D | 15.28 | 39,700 | 39,700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Carruthers R Michael | NVLS | Stock Option (Right to Buy) | D | 15.28 | 55,400 | 55,400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Gabriel Sherif | NVLS | Stock Option (Right to Buy) | D | 15.28 | 24,700 | 24,700 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Congleton Jon | NVLS | Stock Option (Right to Buy) | D | 15.28 | 121,100 | 121,100 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Loh Evan | NVLS | Stock Option (Right to Buy) | D | 15.28 | 7,650 | 7,650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 15.28 | 7,650 | 7,650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 15.28 | 7,650 | 7,650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | TROHA JANICE | NVLS | Stock Option (Right to Buy) | D | 15.28 | 65,400 | 65,400 | |||||
| 2015-09-15 | 2015-09-11 | 4 | MOORE JOHN R | NVLS | Stock Option (Right to Buy) | D | 15.28 | 7,650 | 7,650 | |||||
| 2015-09-15 | 2015-09-11 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 15.28 | 7,650 | 7,650 | |||||
| 2015-07-20 | 2015-07-16 | 4 | Furst Howard P. | NVLS | Stock Option (Right to Buy) | D | 17.49 | 11,475 | 11,475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | LEFF JONATHAN S | NVLS | Stock Option (Right to Buy) | D | 17.49 | 11,475 | 11,475 | |||||
| 2015-07-20 | 2015-07-16 | 4 | CONWAY ROBERT E | NVLS | Stock Option (Right to Buy) | D | 17.49 | 11,475 | 11,475 | |||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 2 Preferred Stock | I | -936,839 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 2 Preferred Stock | I | -817,541 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 2 Preferred Stock | I | -85,962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 2 Preferred Stock | I | -54,385 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 2 Preferred Stock | I | -385,962 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Series 1 Preferred Stock | I | -1,243,423 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Series 1 Preferred Stock | I | -1,085,085 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Series 1 Preferred Stock | I | -1,401,003 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Series 1 Preferred Stock | I | -869,667 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Series 1 Preferred Stock | I | -2,013,613 | 0 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 14.0000 | 77,539 | 1,086 | 832,216 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 14.0000 | 67,666 | 947 | 726,242 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 14.0000 | 104,795 | 1,467 | 1,124,740 | ||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 324,278 | 754,677 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 282,984 | 658,576 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 29,755 | 647,152 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 18,825 | 402,062 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 133,597 | 1,019,945 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International II, L.P. | NVLS | Common Stock | I | 430,399 | 430,399 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund II, L.P. | NVLS | Common Stock | I | 375,592 | 375,592 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 484,944 | 617,397 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 301,027 | 383,237 | ||||||
| 2015-06-25 | 2015-06-23 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 696,993 | 886,348 | ||||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Series 2 Convertible Preferred Stock | I | 2.85 | -364,358 | 0 | |||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 14.0000 | 200,000 | 2,800 | 564,358 | ||||
| 2015-06-24 | 2015-06-22 | 4 | Rock Springs Capital Management LP By Rock Springs Capital Master Fund LP | NVLS | Common Stock | I | 364,358 | 364,358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | -1,052,631 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hadley Harbor Master Investors (Cayman) L.P. | NVLS | Common stock | D | 364,358 | 364,358 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Series 2 convertible preferred stock | D | -818,714 | 0 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 283,390 | 320,990 | ||||||
| 2015-06-23 | 2015-06-22 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14.7479 | 5,500 | 81 | 37,600 | ||||
| 2015-06-23 | 2015-06-19 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14.6659 | 11,700 | 172 | 32,100 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Series 2 convertible preferred stock | D | 14.00 | -303,631 | 0 | |||||
| 2015-06-22 | 2015-06-22 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14.0000 | 303,631 | 4,251 | 329,780 | ||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Series 1 convertible preferred stock | D | -2,200,404 | 0 | ||||||
| 2015-06-22 | 2015-06-22 | 4 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 761,649 | 1,557,228 | ||||||
| 2015-06-19 | 2015-06-18 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14.7500 | 6,200 | 91 | 20,400 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14.7500 | 6,700 | 99 | 14,200 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Hawkes Bay Master Investors (Cayman) L.P. | NVLS | Common stock | D | 14.0000 | 7,500 | 105 | 7,500 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Jennison Global Healthcare Master Fund, Ltd. | NVLS | Common Stock | D | 14.0000 | 26,149 | 366 | 26,149 | ||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1,301,830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1,301,830 | ||||||||
| 2015-06-18 | 3 | Tiger Partners GP, LLC | NVLS | Common Stock | D | 1,301,830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1,301,830 | ||||||||
| 2015-06-17 | 3 | TIGER MANAGEMENT L.L.C. | NVLS | Common Stock | I | 1,301,830 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1,591,158 | ||||||||
| 2015-06-17 | 3 | Estate of Arnold H. Snider, III | NVLS | Common stock | D | 1,591,158 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4,326 | ||||||||
| 2015-06-16 | 3 | Loh Evan | NVLS | Common Stock | D | 4,326 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66,558 | ||||||||
| 2015-06-16 | 3 | TROHA JANICE | NVLS | Common Stock | D | 66,558 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4,326 | ||||||||
| 2015-06-16 | 3 | MOORE JOHN R | NVLS | Common Stock | D | 4,326 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design Fund, L.P. | NVLS | Common Stock | I | 486,233 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Special Situations Fund, L.P. | NVLS | Common Stock | I | 593,380 | ||||||||
| 2015-06-16 | 3 | Deerfield Special Situations Fund, L.P. Through Deerfield Private Design International, L.P. | NVLS | Common Stock | I | 536,475 |
P
공개 시장에서 또는 사적으로 비파생증권 또는 파생증권 매입
S
공개 시장에서 또는 사적으로 비파생증권 또는 파생증권 매각
A
자사로부터 유가증권(옵션 등)을 보조, 지급 또는 기타 취득
C
파생상품 전환
D
자사에게 유가증권을 매각 또는 양도
F
기업으로부터 인도 받은 유가증권의 일부를 사용한 행사 가격 또는 조세 채무의 지급
G
내부자에 의한 또는 내부자에게 증권 증여
K
지분스왑 및 유사 위험 회피거래
M
자사로부터 인도 받은 파생증권(옵션 등)의 행사 또는 전환
V
보고서 양식 4에 자진 신고된 거래
J
기타 (거래 내용을 설명하는 각주와 동반)
